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History, Wild Mice, and Genetics | |
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List of Reviewers | |
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List of Contributors | |
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Foreword | |
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Preface | |
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Building a Better Mouse: One Hundred Years of Genetics and Biology | |
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Systematics of the genus Mus | |
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The Secret World of Wild Mice | |
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Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types | |
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Mouse Strain and Genetic Nomenclature: an Abbreviated Guide | |
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The Mouse Genome | |
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Gene Mapping | |
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Genetic Monitoring | |
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Cytogenetics | |
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Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man | |
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Gamete and Embryo Manipulation | |
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Chemical Mutagenesis in Mice | |
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Gene-Specific Mutagenesis | |
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Gene Transfer Studies Using Mouse Models | |
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Mouse and Human Pluripotent Stem Cells | |
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Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics | |
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Index | |
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Diseases | |
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List of Reviewers | |
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List of Contributors | |
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Foreword | |
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Preface | |
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Viral Diseases | |
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DNA Viruses | |
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Murine Cytomegalovirus and Other Herpesviruses | |
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Mouse Adenoviruses | |
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Mousepox | |
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Parvoviruses | |
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Polyoma Viruses | |
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RNA Viruses | |
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Mouse Hepatitis Virus | |
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Lymphocytic Choriomeningitis Virus | |
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Lactate Dehydrogenase-Elevating Virus | |
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Reoviridae | |
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Retroelements in the Mouse | |
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Sendai Virus and Pneumonia Virus of Mice (PVM) | |
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Cardioviruses: Encephalomyocarditis Virus and Theiler's Mouse Encephalomyelitis Virus | |
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Bacterial Diseases | |
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Chlamydial Diseases | |
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Clostridial Species | |
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Enterobacteriaceae, Pseudomonas aeruginosa, and Streptobacillus moniliformis | |
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Aerobic Gram-positive Organisms | |
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Helicobacter Infections in Mice | |
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Mycoplasma pulmonis, other Murine Mycoplasmas, and Cilia-Associated Respiratory Bacillus | |
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Pasteurellaceae | |
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Mycotic and Parasitic Diseases | |
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Fungal Diseases in Laboratory Mice | |
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Protozoa | |
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Helminth Parasites of Laboratory Mice | |
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Arthropods | |
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Miscellaneous Diseases | |
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The Tumor Pathology of Genetically Engineered Mice: A New Approach to Molecular Pathology | |
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Spontaneous Diseases in Commonly Used Mouse Strains | |
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Zoonoses and other Human Health Hazards | |
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Index | |
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Normative Biology, Husbandry, and Models | |
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List of Reviewers | |
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List of Contributors | |
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Foreword | |
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Preface | |
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Normative Biology | |
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Gross Anatomy | |
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Mouse Physiology | |
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Reproductive Biology of the Laboratory Mouse | |
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Endocrinology: Bone as a Target Tissue for Hormonal Regulation | |
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Hematology of the Laboratory Mouse | |
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Clinical Chemistry of the Laboratory Mouse | |
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Management, Techniques, and Husbandry | |
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Gnotobiotics | |
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Management and Design: Breeding Facilities | |
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Design and Management of Research Facilities for Mice | |
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Nutrition | |
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Health Delivery and Quality Assurance Programs for Mice | |
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Environmental and Equipment Monitoring | |
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Biomethodology and Surgical Techniques | |
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In Vivo Whole-Body Imaging of the Laboratory Mouse | |
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Use of Mice in Biomedical Research | |
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Behavioral Testing | |
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Cardiovascular Disease: Mouse Models of Atherosclerosis | |
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Convulsive Disorders | |
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Eye Research | |
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Genetic Analysis of Rodent Obesity and Diabetes | |
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Mouse Models in Aging Research | |
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Mouse Models of Inherited Human Neurodegenerative Disease | |
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Mouse Skin Ectodermal Organs | |
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Quality Control Testing of Biologics | |
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Index | |
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Immunology | |
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List of Reviewers | |
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List of Contributors | |
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Foreword | |
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Preface | |
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Overview | |
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The Molecular Basis of Lymphoid Architecture in the Mouse | |
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The Biology of Toll-Like Receptors in Mice | |
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Genomic Organization of the Mouse Major Histocompatibility Complex | |
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Some Biological Features of Dendritic Cells in the Mouse | |
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Mouse Models Revealed the Mechanisms for Somatic Hypermutation and Class Switch Recombination of Immunoglobulin Genes | |
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Mouse Natural Killer Cells: Function and Activation | |
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Cytokine-activated JAK-STAT Signaling in the Mouse Immune System | |
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Signal Transduction Events Regulating Integrin Function and T Cell Migration in the Mouse | |
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Mouse Models of Negative Selection | |
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Peripheral Tolerance of T Cells in the Mouse | |
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The Genetics of Mouse Models of Systemic Lupus | |
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Inhibitory Receptors and Autoimmunity in the Mouse | |
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Mouse Models of Immunodeficiency | |
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Mouse Models to Study the Pathogenesis of Allergic Asthma | |
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The Mouse Trap: How Well Do Mice Model Human Immunology? | |
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Index | |