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Mouse in Biomedical Research Diseases

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ISBN-10: 0123694566

ISBN-13: 9780123694560

Edition: 2nd 2007

Authors: James G. Fox, Stephen Barthold, Muriel Davisson, Christian E. Newcomer, Fred W. Quimby

List price: $280.00
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Description:

Diseases, the second volume in the four volume set, The Mouse in Biomedical Research, departs from the first edition, by discussing specific disease causing microorganisms, rather than the format used in the first edition which discussed infectious diseases affecting specific organs and tissues. As such, the volume consists of 26 chapters subdivided into RNA viruses and DNA viruses, as well as bacterial, mycotic, and parasitic infections. These chapters not only provide updates on pathogenesis, epidemiology and prevention of previously recognized murine pathogens, but also include information on newly recognized disease-causing organisms: mouse parvovirus, cilia associated respiratory…    
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Book details

List price: $280.00
Edition: 2nd
Copyright year: 2007
Publisher: Elsevier Science & Technology
Publication date: 12/15/2006
Binding: Hardcover
Pages: 776
Size: 8.50" wide x 10.98" long x 0.54" tall
Weight: 4.334
Language: English

After majoring in English Literature with a concentration in Medieval and Folklore studies, Debra promptly sold out to the corporate world, occasionally dabbling in writing marketing copy and op/ed articles for a local city paper. By day, she designs compensation programs, after dark she stuffs her nose into obscure mythology, and feverishly writes her novels. A DEMON BOUND is her debut novel. Debra lives on a farm in Maryland with Sweetie, three sons, and a Noah's ark of four legged family members. Unlike her protagonist, she drives an old PT Cruiser, couldn't carry a tune if you duct taped it to her back, and enjoys an occasional cosmopolitan (heavy on the vodka). On a good day, she jogs…    

History, Wild Mice, and Genetics
List of Reviewers
List of Contributors
Foreword
Preface
Building a Better Mouse: One Hundred Years of Genetics and Biology
Systematics of the genus Mus
The Secret World of Wild Mice
Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types
Mouse Strain and Genetic Nomenclature: an Abbreviated Guide
The Mouse Genome
Gene Mapping
Genetic Monitoring
Cytogenetics
Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man
Gamete and Embryo Manipulation
Chemical Mutagenesis in Mice
Gene-Specific Mutagenesis
Gene Transfer Studies Using Mouse Models
Mouse and Human Pluripotent Stem Cells
Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics
Index
Diseases
List of Reviewers
List of Contributors
Foreword
Preface
Viral Diseases
DNA Viruses
Murine Cytomegalovirus and Other Herpesviruses
Mouse Adenoviruses
Mousepox
Parvoviruses
Polyoma Viruses
RNA Viruses
Mouse Hepatitis Virus
Lymphocytic Choriomeningitis Virus
Lactate Dehydrogenase-Elevating Virus
Reoviridae
Retroelements in the Mouse
Sendai Virus and Pneumonia Virus of Mice (PVM)
Cardioviruses: Encephalomyocarditis Virus and Theiler's Mouse Encephalomyelitis Virus
Bacterial Diseases
Chlamydial Diseases
Clostridial Species
Enterobacteriaceae, Pseudomonas aeruginosa, and Streptobacillus moniliformis
Aerobic Gram-positive Organisms
Helicobacter Infections in Mice
Mycoplasma pulmonis, other Murine Mycoplasmas, and Cilia-Associated Respiratory Bacillus
Pasteurellaceae
Mycotic and Parasitic Diseases
Fungal Diseases in Laboratory Mice
Protozoa
Helminth Parasites of Laboratory Mice
Arthropods
Miscellaneous Diseases
The Tumor Pathology of Genetically Engineered Mice: A New Approach to Molecular Pathology
Spontaneous Diseases in Commonly Used Mouse Strains
Zoonoses and other Human Health Hazards
Index
Normative Biology, Husbandry, and Models
List of Reviewers
List of Contributors
Foreword
Preface
Normative Biology
Gross Anatomy
Mouse Physiology
Reproductive Biology of the Laboratory Mouse
Endocrinology: Bone as a Target Tissue for Hormonal Regulation
Hematology of the Laboratory Mouse
Clinical Chemistry of the Laboratory Mouse
Management, Techniques, and Husbandry
Gnotobiotics
Management and Design: Breeding Facilities
Design and Management of Research Facilities for Mice
Nutrition
Health Delivery and Quality Assurance Programs for Mice
Environmental and Equipment Monitoring
Biomethodology and Surgical Techniques
In Vivo Whole-Body Imaging of the Laboratory Mouse
Use of Mice in Biomedical Research
Behavioral Testing
Cardiovascular Disease: Mouse Models of Atherosclerosis
Convulsive Disorders
Eye Research
Genetic Analysis of Rodent Obesity and Diabetes
Mouse Models in Aging Research
Mouse Models of Inherited Human Neurodegenerative Disease
Mouse Skin Ectodermal Organs
Quality Control Testing of Biologics
Index
Immunology
List of Reviewers
List of Contributors
Foreword
Preface
Overview
The Molecular Basis of Lymphoid Architecture in the Mouse
The Biology of Toll-Like Receptors in Mice
Genomic Organization of the Mouse Major Histocompatibility Complex
Some Biological Features of Dendritic Cells in the Mouse
Mouse Models Revealed the Mechanisms for Somatic Hypermutation and Class Switch Recombination of Immunoglobulin Genes
Mouse Natural Killer Cells: Function and Activation
Cytokine-activated JAK-STAT Signaling in the Mouse Immune System
Signal Transduction Events Regulating Integrin Function and T Cell Migration in the Mouse
Mouse Models of Negative Selection
Peripheral Tolerance of T Cells in the Mouse
The Genetics of Mouse Models of Systemic Lupus
Inhibitory Receptors and Autoimmunity in the Mouse
Mouse Models of Immunodeficiency
Mouse Models to Study the Pathogenesis of Allergic Asthma
The Mouse Trap: How Well Do Mice Model Human Immunology?
Index