DNA Topoisomerases: Topoisomerase-Targeting Drugs

Name: DNA Topoisomerases: Topoisomerase-Targeting Drugs
Availability: OutOfStock
ISBN: 9780120329304

ISBN-10: 0120329301

ISBN-13: 9780120329304

Edition: 1994

Authors: J. Thomas August, M. W. Anders, Ferid Murad, Joseph T. Coyle, Leroy F. Liu

List price: $72.95

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Description:

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.

Book details

List price: $72.95
Copyright year: 1994
Publisher: Elsevier Science & Technology
Publication date: 12/23/1994
Binding: Hardcover
Pages: 315
Size: 6.00" wide x 9.00" long x 1.00" tall
Weight: 1.408
Language: English



Clinical Development of Topoisomerase-Interactive



Topoisomerases in Human Leukemia



Preclinical and Clinical Development of Camptothecins



Mechanisms of Topoisomerase I Inhibition by Anticancer



Drug Resistance Mechanisms of Topoisomerase I



Mechanism of Action of Topoisomerase II-Targeted Antineoplastic



Determinants of Sensitivity to Topoisomerase-Targeting Antihumor



Resistance of Mammalian Tumor Cells to Inhibitors of DNA Topoisomerase II



A Bacteriophage Model System for Studying Topoisomerase Inhibitors



Drugs Affecting Trypanosome Topoisomerases



Yeast as a Genetic Model System for Studying Topoisomerase Inhibitors



DNA Topoisomerase Inhibitors as Antifungal Agents



Design of Topoisomerase Inhibitors to Overcome MDR1-Mediated Drug Resistance


Appendices



An Introduction to DNA Supercoiling and DNA Topoisomerase-Catalyzed Linking Number Changes of Supercoiled DNA



Alignment of Primary Sequences of DNA Topoisomerases


References


Subject Index


Contents of Previous Volumes