Pulmonary Physiology

ISBN-10: 0071793135

ISBN-13: 9780071793131

Edition: 8th 2013

Authors: Michael Levitzky

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The best review of pulmonary physiology for the USMLE Step 1For more than three decades, Pulmonary Physiology has provided medical students and residents with a solid background in the areas of pulmonary physiology essential for a thorough understanding of clinical medicine. Pulmonary Physiology, 8e teaches you how and why the human respiratory system works--in a style and presentation that makes it easy to absorb andintegrate with your knowledge of other body systems.Features:Every chapter includes learning objectives, summaries of key concepts, study questions, clinical examples,illustrations of essential concepts, and suggested readingsProvides detailed explanations of physiologic mechanisms and demonstrates how they apply to pathologic statesHelps you to understand the basic concepts of pulmonary physiology well enough to apply them with confidence to future patientsDelivers concise yet in-depth coverage of every important topic, including:Function and Structure of the Respiratory SystemMechanics of BreathingAlveolar VentilationBlood Flow to the LungsVentilation-Perfusion RelationshipsDiffusion of Gases and Interpretationof Pulmonary Function TestsTransport of Oxygen and Carbon Dioxide in the BloodAcid-Base BalanceControl of BreathingNonrespiratory Functions of the LungThe Respiratory System Under Stress, including exercise, altitude, diving, and sleep
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Book details

List price: $39.99
Edition: 8th
Copyright year: 2013
Publisher: McGraw-Hill Education
Publication date: 5/1/2013
Binding: Paperback
Pages: 320
Size: 6.00" wide x 9.00" long x 0.50" tall
Weight: 1.056
Language: English

Author Profiles Hershel Raffis Professor of Medicine at the University of Wisconsin, Milwaukee. He is co-author on the Vander Higher Education textbook, which is the leadingHuman Physiology text at that level. He is also the Associate Editor in Advances in Physiology Education. Dr. Raff's primary interest is the development of newmethods in the diagnosis and differential diagnosis of Cushing's syndrome.Doug Eatonis Distinguished Professor and Chairman of Physiology at Emory University. In addition to authoring Vander?s, Renal Physiology, Eaton has beenan Associate Editor for American Journal of Physiology-Cell Physiology and is currently an Associate Editor for American Journal of Physiology-Renal Physiology. He is also on the editorial board of the Journal of Biological Chemistry. He served on National Science Foundation Neurobiology Advisory Pane from 1980-1983. He has been a regular member and Chairman of three NIH Study Sections: the Physiology Study Section (1985-1988); National Institutes of Digestive Diseases and Kidney Special Grants Study Section (1989-1993); and the General MedicineB Study Section (1994-1998). He also served on the NIH General Medical Sciences: Large grants (Glue) review panel (1999-2000). Besides the regular membership on NIH study sections, he has served on over 40 Ad Hoc Review Panels and Site Visit Teams for NIDDK, NHLBI, NIGMS, NCRR, and NCI since 1975. He also served on the National Institute of Standards and Technology Review Board from 1985-1999 and as a member Signal Transduction Review Panel for the American Heart Association.Michael Levitzkyis Professor and Interim Head of the LSU Department of Physiology and is the Director of Basic Science Curriculum. He has received numerous awards including Outstanding Professor in Medicine in 2006 and 2007, selected by Senior Class of 2007 to participate in Pre-Commencement Hooding Ceremony, and is listed in theWho's Who in the World, Who's Who in America, Who's Who in Science and Engineering, Who's Who in Frontier Science and Technology, Who's Who in the South and Southwest, Who's Who in American Education, Who's Who in Medicine and Healthcare, American Men and Women of Science, and the Dictionary of International Biography. Levitzky is currently a Teaching Section Liaison to the Education Committee, at the American Physiological Society and in 2003 was the Chair of the Arthur C. Guyton Teacher of the Year Award, Committee, at the American Physiological Society.

Preface
Function and Structure of the Respiratory System
Objectives
Functions of the Respiratory System
Structure of the Respiratory System
Key Concepts
Suggested Readings
Mechanics of Breathing
Objectives
Generation of a Pressure Difference Between Atmosphere and Alveoli
Pressure-Volume Relationships in the Respiratory System
Interaction of Lung and Chest Wall: The Static Pressure-Volume Curve
Airways Resistance
The Work of Breathing
Key Concepts
Clinical Problems
Suggested Readings
Alveolar Ventilation
Objectives
The Lung Volumes
Measurement of the Lung Volumes
Anatomic Dead Space and Alveolar Ventilation
Measurement of Alveolar Ventilation
Alveolar Ventilation and Alveolar Oxygen and Carbon Dioxide Levels
Regional Distribution of Alveolar Ventilation
The Closing Volume
The Effects of Aging
Key Concepts
Clinical Problems
Suggested Readings
Blood Flow to the Lung
Objectives
The Bronchial Circulation
The Functional Anatomy of the Pulmonary Circulation
Pulmonary Vascular Resistance
The Regional Distribution of Pulmonary Blood Flow: The Zones of the Lung
Hypoxic Pulmonary Vasoconstriction
Pulmonary Edema
Key Concepts
Clinical Problems
Suggested Readings
Ventilation-Perfusion Relationships
Objectives
The Concept of Matching Ventilation and Perfusion
Consequences of High and Low V/Q
Testing for Nonuniform Distribution of Inspired Gas and Pulmonary Blood Flow
Regional V/Q Differences and Their Consequences in the Lung
Key Concepts
Clinical Problems
Suggested Readings
Diffusion of Gases and Interpretation of Pulmonary Function Tests
Objectives
Fick's Law for Diffusion
Limitations of Gas Transfer
Diffusion of Oxygen
Diffusion of Carbon Dioxide
Measurement of Diffusing Capacity
Interpretation of Pulmonary Function Tests
Key Concepts
Clinical Problems
Suggested Readings
Transport of Oxygen and Carbon Dioxide in the Blood
Objectives
Transport of Oxygen by the Blood
Hemoglobin and the Physiologic Implications of the Oxyhemoglobin Dissociation Curve
Influences on the Oxyhemoglobin Dissociation Curve
Transport of Carbon Dioxide by the Blood
The Carbon Dioxide Dissociation Curve
The Bohr and Haldane Effects Explained
Key Concepts
Clinical Problems
Suggested Readings
Acid-Base Balance
Objectives
The Chemistry of Acids, Bases, and Buffers
Buffer Systems of the Human Body
Acidosis and Alkalosis
Respiratory and Renal Compensatory Mechanisms
Clinical Interpretation of Blood Gases and Acid-Base Status
The Causes of Hypoxia
Key Concepts
Clinical Problems
Suggested Readings
Control of Breathing
Objectives
The Generation of Spontaneous Rhythmicity
The Medullary Respiratory Center
The Pontine Respiratory Groups
Spinal Pathways
Reflex Mechanisms of Respiratory Control
Influences of Higher Centers
The Response to Carbon Dioxide
The Response to Hydrogen Ions
The Response to Hypoxia
The Response to Exercise
Key Concepts
Clinical Problems
Suggested Readings
Nonrespiratory Functions of the Lung
Objectives
Pulmonary Defense Mechanisms
Nonrespiratory Functions of the Pulmonary Circulation
Metabolic Functions of the Lung
Key Concepts
Suggested Readings
The Respiratory System Under Stress
Objectives
Exercise and the Respiratory System
Altitude and Acclimatization
Diving and the Respiratory System
Sleep and the Respiratory System
Key Concepts
Clinical Problems
Suggested Readings
Clinical Problem Answers
Appendix
Symbols Used in Respiratory Physiology
The Laws Governing the Behavior of Gases
Frequently Used Equations
Table of Normal Respiratory and Circulatory Values
General Suggested Readings
Index
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