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Regulatory Networks of Gene Expression in Heart and Skeletal Muscle Cells The Role of Histone Modifications and Transcription Factors in Muscle Cell Development and Maintenance

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ISBN-10: 3836483734

ISBN-13: 9783836483735

Edition: 2008

Authors: Jenny J. Fischer

List price: $89.00
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The development and maintenance of muscle cells is controlled by complex regulatory networks involving epigenetic marks and transcription factors. While histone modifications influence the compaction of chromatin and consequently the accessibility of DNA, transcription factors are responsible for a fine tuning of expression. In this study, modern high-throughput methods of molecular biology together with bioinformatic analyses were used to decipher the architecture of these networks. The role of activating histone modifications and their potential interactions with key cardiac transcription factors in the context of muscle development and congenital heart diseases are presented. Several…    
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Book details

List price: $89.00
Copyright year: 2008
Publisher: AV Akademikerverlag GmbH & Co. KG
Binding: Paperback
Pages: 172
Size: 6.00" wide x 9.00" long x 0.37" tall
Weight: 0.572