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Basic Concepts and Principles | |
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Introduction | |
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Background and Scope | |
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Dimensions and Units | |
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Intensive and Extensive Properties | |
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Equilibria and Rates | |
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Batch vs. Continuous Operation | |
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Material Balance | |
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Energy Balance | |
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Elements Of Physical Transfer Processes | |
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Heat Conduction and Molecular Diffusion | |
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Fluid Flow and Momentum Transfer | |
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Laminar vs. Turbulent Flow | |
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Transfer Phenomena in Turbulent Flow | |
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Film Coefficients of Heat and Mass Transfer | |
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Chemical And Biochemical Kinetics | |
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Fundamental Reaction Kinetics | |
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Cell Kinetics | |
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Cell Growth | |
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Growth Phases in Batch Culture | |
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Factors Affecting Rates of Cell Growth | |
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Cell Growth in Batch Fermentors and Continuous Stirred Tank Fermentor (CSTF) | |
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Unit Operations and Apparatus for Bio-Systems | |
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Heat Transfer | |
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Overall Coefficients U and Film Coefficients h | |
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Mean Temperature Difference | |
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Estimation of Film Coefficients h | |
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Estimation of Overall Coefficients U | |
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MASS TRANSFER | |
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Single Phase and Overall Mass Transfer Coefficients | |
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Types of Mass Transfer Equipment | |
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Liquid Phase Mass Transfer with Chemical Reactions | |
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Correlations for Single-Phase Mass Transfer Coefficients | |
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Performance of Packed Column | |
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Bioreactors | |
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Some Fundamental Concepts | |
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Bubbling Gas-Liquid Reactors | |
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Mechanically Stirred Tanks | |
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Gas Dispersion in Stirred Tanks | |
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Bubble Columns | |
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Airlift Reactors | |
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Packed Bed Reactors | |
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Microreactors | |
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Membrane Processes | |
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Dialysis | |
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Ultrafiltration | |
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Microfiltration | |
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Reverse Osmosis | |
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Membrane Modules | |
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Cell-Liquid Separation And Cell Disruption | |
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Conventional Filtration | |
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Microfiltration | |
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Centrifugation | |
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Cell Disruption | |
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Sterilization | |
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Kinetics of Thermal Death of Cells | |
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Batch Heat Sterilization of Culture Media | |
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Continuous Heat Sterilization of Culture Media | |
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Sterilizing Filtration | |
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Adsorption And Chromatrography | |
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Equilibrium in Adsorption | |
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Rates of Adsorption into Adsorbent Particles | |
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Single- and Multi-Stage Processes for Adsorption | |
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Adsorption in Fixed-Bed | |
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Bioseparation by Chromatography | |
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Practical Aspects in Bioengineering | |
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Fermentor Engineering | |
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General | |
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Stirrer Power Requirements for Non-Newtonian Liquids | |
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Heat Transfer in Fermentors | |
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Gas-Liquid Mass Transfer in Fermentors | |
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Criteria for Scaling-Up Fermentors | |
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Modes of Fermentor Operation | |
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Fermentors for Animal Cell Culture | |
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Downstream Operations In Bioprocesses | |
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Steps in Downstream Processing | |
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Separation of Microorganisms by Filtration and Microfiltration | |
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Separation by Chromatography | |
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Separation in Fixed-Bed | |
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Sanitation in Downstream Processes | |
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Medical Devices | |
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Blood and Its Circulation | |
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Oxygenation of Blood | |
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Artificial Kidney | |
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Bioartificial Liver | |