Changing the Course of Autism A Scientific Approach for Parents and Physicians

ISBN-10: 1591810612

ISBN-13: 9781591810612

Edition: 2007

Authors: Bryan Jepson, Jane Johnson

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This book shows that autism can be treated by reducing the neurological inflammation that is part of the disease process, rather than simply masking the symptoms with drugs like Ritalin and Prozac. The authors have have seen autistic behaviors improve dramatically or disappear completely with their treatment. The book cites solid scientific research showing the link between vaccines and autism. The foreword is by Katie Wright, whose parents--Bob and Suzanne Wright--founded Autism Speaks.
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Book details

List price: $18.95
Copyright year: 2007
Publisher: Sentient Publications
Publication date: 5/11/2007
Binding: Paperback
Pages: 360
Size: 5.75" wide x 8.75" long x 1.00" tall
Weight: 1.100
Language: English

Dr Jepson graduated from the University of Utah Medical School in 1995 and completed residency training in Grand Rapids , Michigan in 1998. Board certified in emergency medicine, he lives in Austin, Texas, with Laurie and their two sons. JANE JOHNSON became interested in medical treatment for learning disabilities in 2000, when her son was diagnosed with non-verbal learning disorder (NLD). In her effort to educate herself, she became more and more alarmed at the epidemic growth and prevalence of developmental disorders. She is the Co-Managing Director of the Board of Thoughtful House. She lives in New York City with her husband and their three children. The foreword is by Katie Wright, whose parents, Bob and Suzanne Wright, founded Autism Speaks after Katie's son was diagnosed with autism. As CEO of NBC/Universal, Bob made Autism Speaks the biggest autism organization in the USA, and Katie and her parents have worked tirelessly to raise autism awareness.

Introduction: Coming to Terms with Autism
An Important Note to Readers
The Rise and Fall of the "Refrigerator Mother" Theory
Kanner's Diagnosis
The Refrigerator Mother Theory
Progress in Behavioral Intervention
Autism Isn't Purely Genetic
The Autism Epidemic
Concern in California
The Mind Institute Study
Diagnostic Substitution?
What about the Rest of the Country?
What about Other Countries?
Changes in the Diagnostic Criteria
Other Explanations?
The Hidden Horde Theory Refuted
California Update
The Autism Crisis
Autism Is a Disease, Not A Disability
Autism: An Environmental Illness
Disease, Not Disability
The Multiple Hit Hypothesis
Basics of the Immune System
The First Line of Defense
The Non-Specific or Innate Immune Response
The Antigen-Specific or Adaptive Immune Response
Antigen-Presenting Cells (APCs)
Th1 Vs. Th2 Response
Other Immune Cells
The Problem of Immune Dysregulation
Do Individuals with Autism Have Immune Dysregulation?
Excessive Inflammation
Autoimmune Reactions
Food Reactions
Abnormal Response to Infections
Measles and the MMR Controversy
The Epidemiology Wars
Biological Plausibility
Is Autism a Gut Disease?
Diagnostic Confirmation of Upper GI Disease
Abnormal Stools
Autistic Enterocolitis
Leaky Gut Syndrome
Intestinal Dysbiosis
Why Can't They Detoxify?
Detoxification 101
The Methylation Cycle
The Importance of Glutathione
Impaired Methylation in Autism
Does Mercury Cause Autism?
The Mercury Cycle
The Toxicity of Mercury
The EPA Reports Concern about Mercury
Mercury and Autism
What is Thimerosal?
Thimerosal Studies
Further Evidence Against Mercury
Where Does Ethylmercury Go?
Is Ethylmercury as Bad as Methylmercury?
Cell Death in the Brain and the Immune System
Thimerosal Inhibits Glutamate Transport
Thimerosal Affects Nerve Differentiation
Can You Be Genetically at Risk for Thimerosal Injury?
Other Effects of Thimerosal on the Immune System
Thimerosal Inhibits Methylation
Thimerosal Depletes Intracellular Glutathione in Brain Cells
Other Effects of Thimerosal
Autistic Children and Mercury Exposure
Environmental Mercury Exposure and Autism
The Institute of Medicine (IOM) Report
Autism and the Brain
Neuroanatomy (Brain Structure)
Abnormal Neurochemistry
Sleep Disturbances
The Autism Web-Making Sense of the Disease
Treating Autism
The Multi-Tiered Treatment Approach
Correcting Nutritional Deficiencies
Omega Fatty Acids
Essential Amino Acids
Other Nutrients
Providing a Good Diet
Treating the Gut
Treating Dysbiosis
Digestive Enzymes
Fixing a Leaky Gut
Treating Constipation
Treating Reflux
Treating Autistic Enterocolitis
Preventing Oxidative Stress
Supporting the Detoxification Pathway
Removing Toxins
Treating the Immune System
Immune System Support
Removing Immune Triggers
Breaking the Inflammatory Cycle
Treating the Brain
Removing False Neurotransmitters and Neurotoxins
Modulating Neurotransmitters
Supply the Brain with Oxygen
Treating Seizures
Lessons from Israel
Parent Ratings of Behavioral Effects of Biomedical Interventions
DSM III-R and DSM IV Criteria for Autism
About Thoughtful House
About the Authors
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