Smallpox The Death of a Disease

ISBN-10: 1591027225

ISBN-13: 9781591027225

Edition: 2009

List price: $27.99
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Foreword by Richard Preston, author of The Hot Zone; Preface by David M. Oshinsky. The personal story of how Dr Henderson led the World Health Organization's campaign to eradicate smallpox-the only disease in history to have been deliberately eliminated.
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Book details

List price: $27.99
Copyright year: 2009
Publisher: Prometheus Books, Publishers
Publication date: 6/23/2009
Binding: Hardcover
Pages: 334
Size: 9.25" wide x 6.00" long x 1.50" tall
Weight: 1.584
Language: English

Richard Preston graduated summa cum laude from Pomona College in California and received a Ph.D. in English from Princeton University. He began his career as a journalist writing for the New York Times, Washington Post, National Geographic Traveler and Blair & Ketchum's Country Journal. He has also been a contributor to The New Yorker since 1985. One of Preston's earlier novels, "First Light," was a book on astronomy that won him the American Institute of Physics Award, and he has an asteroid the size of Mount Everest named after him. He also wrote "The Hot Zone," which is a true story about an outbreak of the Ebola virus near Washington, D.C. and inspired the movie Outbreak that starred Dustin Hoffman. "The Cobra Event" is a thriller about biological weapons and terrorism. He spent three years researching biological weapons and his sources included high-ranking government officials, and the scientists who invented and tested these weapons. The story tells of a medical doctor who works with the FBI to stop an act of bio-terrorism in New York City. Preston is now considered an expert in the areas of disease and biotechnology; and the FBI and President Clinton, in regards to disease and bio-warfare, have sought out his opinion. Preston has won several awards that include the McDermott Award in the Arts from the Massachusetts Institute of Technology, and the Overseas Press Club of America's Whitman Basso Award for the best reporting in any medium on environmental issues for "The Hot Zone." His title Micro with Michael Crichton made the New York Times Best Seller list for 2011.

The Disease, The Virus, and its History
The Oldest of Scourges and the Most Devastating
A Case of Smallpox
The Virus
How long can the smallpox virus survive?
Smallpox in Ancient Times
Smallpox Becomes Endemic
Smallpox and the Settlement of the New World
Early Protection against Smallpox
Jenner's Vaccine
Needed-A Better Vaccine
Calves become vaccinia factories
Better distribution-door-to-door cows
A heat-stable vaccine
A Second Form of Smallpox
Smallpox Begins to Lose Ground
The World Decides to Eradicate Smallpox
The Beginning of the Eradication Saga
1953: A Global Eradication Program Is Proposed-and Rejected
1958: The Soviet Union Makes a New Proposal to Eradicate Smallpox
Mission Impossible?
The US Communicable Disease Center Becomes Engaged with Smallpox
Concerns about vaccine complications
The United States Offers to Support a West Africa Program- A Startling Development
The Director-General Challenges the 1966 Assembly
Creating A Global Program
A Program in Its Infancy
Countries, Fiefdoms, and Short-Circuiting the Bureaucracy
The Creation of the Program Budget
How Many Smallpox Cases?
The Realities of Executing a Simple, Two-Part Strategy
Mass-vaccination strategy
Surveillance and containment-a new component
Availability of Vaccine-An Apparently Soluble Problem Is Anything But
Vaccination Techniques-There Have to Be Better Ways
Communication-Conflict and Controversy
Off and on the World Health Assembly agendas
Three reporting systems become one
A surveillance report threatens the whole program
Diplomatic Challenges-The Cold War and Other Problems
Yet Another Problem-Obtaining a Competent Staff
Results a Transformation
Where to Begin? A Tale of Two Countries-Brazil and Indonesia
The Brazilian Program-A Regrettable Saga
Vaccine problems
Surveillance-containment saves the day
The program staggers to a finish
A last regrettable chapter-certifying eradication in South America
Indonesia-A Remarkable Achievement with Few Resources
Certification of Eradication-A Serious Effort Is Made
Africa-A Formidable and Complicated Challenge
An Early Start in West Africa
Surveillance-containment is renamed "Eradication-Escalation"
Smallpox Is Eradicated from Africa's Two Largest Countries
Zaire-major epidemic center at the heart of Africa
Sudan-a smallpox-free country becomes infected
Eastern Africa-A Mass-Vaccination Achievement
Southern Africa
The Botswana debacle
The Lessons of Africa
India and Nepal-A Natural Home of Endemic Smallpox
An Ambitious National Program Is Created-1962
The Program Nearly Collapses-1967-1969
A Resurrection of the Program-1970
An Unexpected Catastrophe in West Bengal-Refugees from East Pakistan-1971
The "Final Phase"-Target Zero-Delusional Optimism-1972
The Ultimate Strategy-1973
The Darkest Days of All-January to June 1974
Yet another catastrophe
A Summer Program-1974
Afghanistan, Pakistan, and Bangladesh-The last stronghold of Variola Major
Pakistan (West Pakistan Province before December 1971)
Bangladesh: The End of Variola Major
A renewed eradication program begins-1968
Civil war-March 1971
Reinfection-December 1971
The epidemic spreads-1972
The disaster of November 1973 and recovery
Bulldozers, floods, and famine trigger yet another disaster-1974
One Last Disaster-1975
Ethiopia and Somalia-The Last Countries with Smallpox
Troubles in beginning the program
The tip of the iceberg-1971-1972
Disaster: drought, famine, hordes of refugees-1974
Floods, fighting, and unexpected news-1975
Somalia: An Epidemic That Should Never Have Happened
Smallpox before 1975
Growing suspicions
Smallpox uncovered in Mogadishu-September 1976
Lies, cover-ups, and secret records
The Last Case
Eradication-What Does It Mean and How Do We Define It?
Surveillance and Search
A routine reporting system
Special searches
Rumor registries
International Commissions
Global Certification of Smallpox Eradication
The World Health Assembly-1980
The book and the archives
Monkeypox-a potential threat?
Reserve stocks of vaccine
Laboratories retaining stocks of smallpox virus
To Destroy or To Retain the Remaining Stocks of Smallpox Virus
The initial steps toward smallpox virus destruction
Objections to virus destruction
The January 1995 executive board is blocked from taking action
Attempts to reconcile an impasse
The executive board and the World Health Assembly-1996 and onward
Smallpox as a Biological Weapon
Biological Warfare-The Emerging Threat
The Soviet Union's secret-a massive bioweapons program
The Soviet bioweapons legacy-who else might have the smallpox virus?
An Ill-Prepared United States Awakens to a Threat
A symposium changes minds
An expert "working group"
From working group to a center
The Center for Civilian Biodefense Studies
The "Dark Winter" Exercise
New Challenges-Post-September 11
How to Deal with a Smallpox Epidemic
The vaccine production miracle
The Office of Public Health Emergency Preparedness
Let's Vaccinate Everyone!
A national vaccination program starts and collapses
Smallpox on the International Scene
Atlantic Storm-a reminder that smallpox is not to be forgotten
Lessons and Legacies of Smallpox Eradication
The Siren Song of Eradication
The Legacy of the Smallpox Eradication Program
An Expanded Program on Immunization Begins
A paradigm for EPI-the program in Latin America
New Horizons in Public Health
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