Managing the Side Effects of Psychotropic Medications

ISBN-10: 1585624020

ISBN-13: 9781585624027

Edition: 2012

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Managing the Side Effects of Psychotropic Medicationsprovides comprehensive, pragmatic information on anticipating and countering adverse drug effects when they occur. Cowritten by a research psychopharmacologist and a consultation-liaison psychiatrist, this book fills a void in the literature, helping mental health practitioners assess the risks and benefits of specific psychotropic medications and undertake strategies for managing adverse effects.This volume includes a wealth of information relevant to clinical psychiatrists, psychiatric residents, and psychiatric nurses, as well as medical students engaged in a psychiatry rotation. Highlights include: • A review of fundamental concepts from internal medicine relevant to psychopharmacology across all major organ systems affected by antidepressants, antipsychotics, mood stabilizers, stimulants, sedative-hypnotics, and other major psychotropic classes• Practical discussion of the strengths and weaknesses of viable antidote strategies for common adverse drug effects, including weight gain, metabolic dysregulation, sexual dysfunction, sleep disorders, skin rashes, movement disorders, and cognitive disturbances. Readers will understand the scientific rationale and evidence base behind available methods to counteract adverse drug effects• An entire section on vulnerable populations, including children, the medically ill, and older adults, including the special considerations in prescribing and intervening when adverse effects arise• Guidance for managing emergency situations, beginning with how to determine whether such a situation—e.g., allergic reaction or overdose—exists. Easy-to-use tables provide critical information needed to respond rapidly and appropriately to emergency situations including overdoses, neurotoxicities, and systemic reactions• A 25-question, multiple-choice self-assessment that employs a combination of case studies and straightforward questions on mechanisms of action, key symptoms, and medication selection, providing the reader with an effective way to measure learning• A series of appendices that distill complex information into readily-comprehensible form on vital topics including commonly reported adverse effects, common psychotropic drug interactions, resources for practitioners, and rating scales for measuring adverse drug effects. Most valuable of all, Managing the Side Effects of Psychotropic Medications provides concise, bottom-line summary recommendations that synthesize all available empirical and anecdotal information on psychotropic medications. Mental health practitioners will appreciate its comprehensiveness and wise counsel.
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Book details

List price: $153.00
Copyright year: 2012
Publisher: American Psychiatric Association Publishing
Publication date: 5/1/2012
Binding: Paperback
Pages: 532
Size: 6.25" wide x 9.25" long x 1.25" tall
Weight: 1.848
Language: English

List of Abbreviations
List of Drugs
General Considerations
The Psychiatrist as Physician
Primary Care Psychiatry
Differentiating Adverse Drug Effects From Primary Illness Symptoms
The Nocebo Phenomenon and Proneness to Adverse Effects
Negative Therapeutic Reactions
Attribution and Causality
Paradoxical Adverse Effects
Extrapolating "Evidence-Based Research Findings" to "Real-World" Patients
Dose Relationships and Adverse Effects
FDA Warnings and Precautions
Risk-Benefit Analyses
General Approach to Assessing Adverse Drug Effects
Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics
Pharmacokinetics and Pharmacodynamics
Toxic Polypharmacy
Gender and Racial Differences in Adverse Effects
Brand Versus Generic Formulations
Enantiomeric Versus Racemic Agents, and Parent Versus Metabolite Compounds
Drug Blood Levels
Pharmacogenomic Predictors of Adverse Effects
Vulnerable Populations
Patients' Diverse Proneness to Drug Side Effects
Medically III Patients
Older Adults
Patients Prone to Somatization
Adverse Psychiatric Effects of Nonpsychotropic Medications
Antiparkinsonian Agents
Antiretroviral Agents
Cardiovascular Drugs
Dermatological Agents
Gastrointestinal Agents
Oral Contraceptives and Intravaginal Rings
Smoking Cessation Aids
Adverse Psychiatric Effects of Psychiatric Medications
Activation and Mania/Hypomania or Mixed States
Anxiety and Panic
Clinical Trial Subjects With Psychiatric Illness
Discontinuation Phenomena
Disinhibition and Impaired Impulse Control
Emotional Dulling
Suicidal Thinking or Behavior
What Nonmedical Therapists Should Know About Adverse Drug Effects
Organ Systems
Cardiovascular System
Arrhythmias and Palpitations
Cerebrovascular Accidents
Myocarditis and Cardiomyopathy
Orthostatic Hypotension
Dermatological System
Skin Rashes
Ear, Nose, and Throat
Oral Lesions
Stomatodynia (Burning Mouth Syndrome)
Electrolyte Abnormalities
Hyponatremia and SIADH
Metabolic Acidosis and Alkalosis
Bone Demineralization and Osteoporosis
Glycemic Dysregulation and Diabetes Mellitus
Hyperprolactinemia, Galactorrhea, and Gynecomastia
Menstrual Disturbances and Polycystic Ovary Syndrome
Parathyroid Abnormalities
Thyroid Abnormalities
Gastrointestinal System
Diarrhea, Hypermotility, and Constipation
Gastrointestinal Bleeding
Hepatic Impairment and Transaminitis
Malabsorption Disorders
Nausea and Gastrointestinal Upset
Genitourinary and Renal Systems
Dysuria and Urinary Retention
Enuresis and Urinary Incontinence
Nephrotic Syndrome
Nephrotoxicity and Nephrogenic Diabetes Insipidus
Renal Calculi
Renal Insufficiency
Sexual Dysfunction
Hematological System
Myelosuppression: Agranulocytosis and Thrombocytopenia
Platelet Aggregation Disorders and Bleeding Risk
Red Blood Cells
Musculoskeletal System
Joint Pain
Leg Cramps
Neurological System
Akathisia and Extrapyramidal Adverse Effects
Cognitive Complaints
Delirium and Encephalopathy
Dyskinesias and Dystonias
Fatigue and Sedation
Motor Tics
Muscle Twitching, Fasciculations, and Myoclonus
Oculogyric Crises
Paresthesias and Neuropathies
Ophthalmological System
Diplopia/Blurred Vision
Sleep Disturbances
Hypersomnia and Sleep Attacks
Nightmares and Vivid Dreams
Systemic Reactions
Allergic Reactions and Angioedema
Antiepileptic Hypersensitivity Reactions
Body Temperature Dysregulation
Discontinuation Syndromes
Drug-Induced Lupus Erythematosus
Neuroleptic Malignant Syndrome
Serotonin Syndrome
Weight Gain
Weight Loss
Pregnancy and the Puerperium
Breast-Feeding and Adverse Events
Growth Effects
Withdrawal in the Newborn
Emergency Situations
Summary Recommendations
Summary Recommendations
The Future
Self-Assessment Questions and Answers
Resources for Practitioners
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