Antibiotics Actions, Origins, Resistance
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Description: As antibiotics become deactivated through resistance and emerging bacterial diseases Christopher Walsh offers new insights into antibiotic modification and design. He shows how antibiotics work on targets and reviews recent strategies for finding innovative antibiotics to replace the last generation.
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All the information you need in one place! Each Study Brief is a summary of one specific subject; facts, figures, and explanations to help you learn faster.
List price: $99.95
Copyright year: 2003
Publisher: ASM Press
Publication date: 2/11/2003
Size: 7.25" wide x 10.00" long x 1.00" tall
|Introduction to Antibiotics|
|Antibiotics: Initial Concepts|
|Validated Targets and Major Antibiotic Classes|
|Introduction to Major Antibiotic Classes and Modes of Action|
|Antibiotics That Act on Cell Wall Biosynthesis|
|Antibiotics That Block Bacterial Protein Biosynthesis|
|Antibiotics That Block DNA Replication and Repair: the Quinolones|
|Other Targets of Antibacterial Drugs|
|Natural and Producer Immunity versus Acquired Resistance|
|Enzymatic Destruction or Modification of the Antibiotic by Resistant Bacteria|
|Antibiotic Resistance by Efflux Pumps|
|Antibiotic Resistance by Replacement or Modification of the Antibiotic Target|
|Regulation of Antibiotic Biosynthesis in Producer Organisms|
|Polyketide Antibiotic Biosynthesis: Assembly-Line Enzymology|
|Enzymatic Assembly Lines for Nonribosomal Peptide Antibiotics|
|Biosynthesis of Other Classes of Antibiotics|
|New Strategies for Finding Novel Antibiotics and Extending Their Lifetimes|
|New Looks at Targets|
|Contexts and Challenges for the Use of New Antibiotics|