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MicroRNA in Development and in the Progression of Cancer

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ISBN-10: 1489980652

ISBN-13: 9781489980656

Edition: 2014

Authors: Shree Ram Singh, Pranela Rameshwar

List price: $189.00
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Description:

miRNAs are a class of endogenous, small non-protein coding RNA molecules ( 22 nucleotides) which are novel post-transcriptional regulators of gene expression.?Since we have hundreds of miRNAs, the major challenge is now to understand their specific biological function. In fact the experimental evidence suggests that signaling pathways could be ideal candidates for miRNA-mediated regulation. Several studies suggest?that miRNAs affect the responsiveness of cells to signaling molecules such as WNT, Notch, TGF- and EGFR.?Altered expression of particular miRNAs has been implicated in the onset and development of cancer and could be used as potential biomarkers for the disease.Recently, many…    
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Book details

List price: $189.00
Copyright year: 2014
Publisher: Springer
Publication date: 4/21/2014
Binding: E-Book 
Pages: 407
Language: English