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Basic Immunology Functions and Disorders of the Immune System with STUDENT CONSULT Online Access

ISBN-10: 1455707074

ISBN-13: 9781455707072

Edition: 4th 2014

Authors: Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai

List price: $71.95
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Description:

Here's a readable and concise introduction to the workings of the human immune system, with emphasis on clinical relevance. The format makes learning easy with short, easy-to-read chapters, color tables, key point summaries, and review questions in every chapter.Relates basic science to clinical disorders through clinical cases for better application in a real-world setting.Includes a full Glossary to keep you on the cutting edge of immunologic terminology.Includes appendices summarizing the features of CD Molecules, a handy Glossary, and Clinical Cases that test your understanding of how the immune system functions in health and disease. Illustrated with beautiful full-color artwork for enhanced visual learning. 1. New discussion of the inflammasome and how it recognizes damaged cells, crystals and foreign materials, with a figure. Discussion of its relevance to human diseases, including type 2 diabetes and atherosclerosis. 2. Revised discussion of the innate immune response and families of microbe-sensing receptors. 3. New information on "Th17" cells, and their development and roles in host defense and disease, with a new figure. 4. Updated information on T-dependent antibody responses, new discussion of follicular helper T cells and the germinal center reaction. 1 or 2 new figures. 5. New information on the genetic basis of autoimmune diseases.
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Book details

List price: $71.95
Edition: 4th
Copyright year: 2014
Publisher: Elsevier - Health Sciences Division
Publication date: 11/13/2012
Binding: Paperback
Pages: 336
Size: 7.25" wide x 9.00" long x 0.50" tall
Weight: 1.650
Language: English

Introduction to the Immune System
Nomenclature, General Properties, and Components
Innate Immunity
The Early Defense Against Infections
Antigen Capture and Presentation to Lymphocytes
What Lymphocytes See
Antigen Recognition in the Adaptive Immune System
Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires
T Cell-Mediated Immunity
Activation of T Lymphocytes by Cell-Associated Antigens
Effector Mechanisms of T Cell-Mediated Immunity
Functions of T Cells in Host Defense
Humoral Immune Responses
Activation of B Lymphocytes and Production of Antibodies
Effector Mechanisms of Humoral Immunity
Elimination of Extracellular Microbes and Toxins
Immunological Tolerance and Autoimmunity
Self-Nonself Discrimination in the Immune System and Its Failure
Immune Responses against Tumors and Transplants
Immunity to Noninfectious Transformed and Foreign Cells
Hypersensitivity
Disorders Caused by Immune Responses
Congenital and Acquired Immunodeficiencies
Diseases Caused by Defective Immune Responses
Suggested Readings
Glossary
Major Cytokines
Principal Features of Select CD Molecules
Clinical Cases
Index