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Can a Virus Cause Schizophrenia? Facts and Hypotheses

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ISBN-10: 1402073003

ISBN-13: 9781402073007

Edition: 2003

Authors: Bradley D. Pearce

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The viral hypothesis has emerged as a very promising field of research in the etiology of schizophrenia, with the body of evidence now so persuasive that the scientific community can no longer discount it. This volume assesses the various sub-theories of the viral hypothesis.
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Book details

Copyright year: 2003
Publisher: Springer
Publication date: 11/30/2002
Binding: Hardcover
Pages: 144
Size: 6.25" wide x 9.50" long x 0.75" tall
Weight: 0.880
Language: English

Introduction and History
A brief history of the viral hypothesis
Fundamentals of Viral Infections and Immune Responses in Humans
A primer on general virology
Immune response to viral infections
Persistent viral infections
Encephalitis and Schizophrenia
Viruses and schizophrenia: a plurality of theories
Psychosis in viral encephalitis
The validity gap for the encephalitis connection
Borna diseases virus
Viruses in other psychiatric diseases
Epidemiological Evidence
Epidemiological studies of the viral hypothesis
Seroepidemiological studies
Immune alterations in schizophrenia
The Role of Viral Infections During Neurodevelopment
Brain development
Immunology of the maternal-fetal unit
The viral-developmental hypothesis
Epidemiological studies of perinatal infections in adult schizophrenia
Models and Mechanisms
Specific models
A history lesson from oncology concerning the viral hypothesis
What a viral etiology of schizophrenia does not mean