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Clinical Nephrotoxins Renal Injury from Drugs and Chemicals

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ISBN-10: 1402012772

ISBN-13: 9781402012778

Edition: 2nd 2003 (Revised)

Authors: Marc E. de Broe, W. M. Bennett, G. A. Porter, G. A. Verpooten

List price: $439.00
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Description:

A comprehensive handbook on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys, this second edition offers expanded information regarding the paediatric age group and provides up-to-date references.
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Book details

List price: $439.00
Edition: 2nd
Copyright year: 2003
Publisher: Springer
Binding: Hardcover
Pages: 730
Size: 7.75" wide x 10.25" long x 1.50" tall
Weight: 4.180
Language: English

Preface
List of Contributors
General
Clinical relevance
Renal handling of drugs and xenobiotics
Pharmacovigilance
Immunologically-mediated toxin-induced renal disease
Cellular mechanisms of nephrotoxicity
Animal models for the assessment of acute renal dysfunction and injury
Renal cell culture models: contribution to the understanding of nephrotoxic mechanisms
Specific Drugs
Aminoglycosides and vancomycin
Beta-lactam antibiotics
Amphotericin B
Sulfonamides, sulfadiazine, trimethoprim-sulfamethoxazole, pentamidine, pyrimethamine, dapsone, quinolones
Antiviral agents
Analgesics and 5-aminosalicylic acid
Non-steroidal anti-inflammatory drugs
Gold salts, D-penicillamine and allopurinol
Angiotensin I converting enzyme inhibitors and angiotensin II receptor antagonists
Diuretics
Anticancer drugs
Anesthetic agents
Illicit drug abuse
Calcineurin inhibitors and sirolimus
Immunomodulators: interleukins, interferons, and the OKT3 monoclonal antibody
Radiocontrast agents
Lead nephropathy
Cadmium-induced renal effects
Mercury-induced renal effects
Hydrocarbons, silicon-containing compounds and pesticides
Lithium-induced renal effects
Aristolochic acid nephropathy after Chinese herb remedies
Balkan endemic nephropathy
Nephrotoxins in Africa
Paraphenylene diamine hair dye poisoning
Prevention
Urinary biomarkers and nephrotoxicity
Pharmacological aspects of nephrotoxicity
Drug dosage in renal failure
List of Abbreviations
Index