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| Preface | |
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| Introduction | |
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| Pathology | |
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| Introduction to Pathology | |
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| Humors and Disease | |
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| Humors | |
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| Cellular Theory of Disease | |
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| Divisions of Pathology | |
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| Plan of Study in Pathology | |
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| The Importance of Lesions | |
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| Autopsies | |
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| Trauma-Related Deaths | |
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| Drug Abuse | |
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| Cocaine | |
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| Heroin | |
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| Gunshot Wounds | |
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| Ballistics | |
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| Density and Elasticity of Tissues | |
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| Guns and Suicide | |
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| Electrical Injuries | |
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| Lightning | |
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| High Voltage | |
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| Low Voltage | |
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| Burns | |
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| Rule of Nines | |
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| Severity of Burns | |
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| Frostbite | |
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| Stabbing | |
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| Motor Vehicle Accidents | |
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| Nature of Disease | |
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| Disease, Disorders, and Illness | |
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| Descriptive Terminology | |
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| Lifespan Versus Longevity | |
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| Predisposing Conditions and Disease | |
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| Immediate Causes of Disease | |
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| Cellular Reaction to Injury | |
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| Cells and Their Environments | |
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| Potential Causes of Cellular Injury | |
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| Regressive Cellular Changes | |
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| Cellular Swelling | |
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| Fatty Degeneration | |
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| Amyloid Degeneration | |
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| Infiltration | |
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| Exogenous Pigmentation | |
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| Endogenous Pigmentation | |
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| Calcification | |
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| Gout | |
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| Cellular Death | |
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| Adaptive Responses to Cellular Injury | |
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| Atrophy | |
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| Hypertrophy | |
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| Hyperplasia | |
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| Metaplasia | |
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| Regeneration | |
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| Structural Abnormalities and Birth Defects | |
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| Structural Abnormalities and Birth Defects | |
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| Spina Bifida | |
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| Limb Deformities | |
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| Cleft Palate and Lip | |
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| Color Blindness | |
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| Vascular Nevus | |
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| Down Syndrome | |
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| Cystic Fibrosis | |
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| Sudden Infant Death Syndrome | |
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| Hernias | |
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| Inflammation | |
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| Function of Inflammation | |
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| Causes of Inflammation | |
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| Process of Inflammation | |
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| Inflammatory Lesions | |
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| Pus | |
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| Inflammatory Exudates | |
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| Outcomes of Inflammation | |
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| Disturbances in Circulation | |
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| Causes of Edema | |
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| Hyperemia | |
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| Ischemia and Hypoxia | |
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| Thrombosis | |
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| Embolism | |
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| Hemorrhage | |
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| Petechiae | |
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| Ecchymosis | |
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| Epistaxis | |
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| Hemoptysis | |
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| Hematemesis | |
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| Melena | |
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| Hematuria | |
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| Exsanguination | |
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| Postmortem Conditions Associated with Disturbances in Circulation | |
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| Neoplasms and Cysts | |
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| Cancer | |
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| Characteristics of Benign and Malignant Tumors | |
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| Tissue Origins of Tumors | |
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| Naming Tumors | |
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| Significant Benign Tumors | |
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| Benign Tumors of Epithelial Tissue | |
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| Adenomas | |
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| Papillomas | |
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| Polyps | |
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| Benign Tumors of Connective Tissue | |
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| Osteomas | |
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| Chondromas | |
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| Lipomas | |
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| Angiomas | |
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| Fibromas | |
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| Benign Tumors of Muscle Tissue | |
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| Rhabdomyomas | |
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| Leiomyomas | |
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| Benign Tumor of Nervous Tissue | |
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| Neuromas | |
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| Significant Malignant Tumors | |
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| Malignant Tumors of Epithelial Tissue | |
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| Melanomas | |
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| Squamous Cell Carcinomas | |
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| Adenocarcinomas | |
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| Transitional Cell Carcinomas | |
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| Basal Cell Carcinomas | |
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| Malignant Tumors of Connective Tissue | |
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| Osteosarcomas | |
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| Chondrosarcomas | |
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| Liposarcomas | |
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| Angiosarcomas | |
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| Fibrosarcomas | |
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| Lymphomas | |
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| Malignant Tumors of Muscle Tissue | |
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| Rhabdomyosarcomas | |
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| Leiomyosarcomas | |
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| Malignant Tumor of Nervous Tissue | |
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| Gliomas | |
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| Cysts | |
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| Ovarian Cysts | |
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| Sebaceous Cysts | |
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| Nonneoplastic Changes | |
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| Postmortem Conditions Associated with Neoplasms | |
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| Diseases of the Blood | |
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| Disorders of the Blood | |
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| Leukocytosis | |
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| Leukopenia | |
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| Anemia | |
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| Aplastic Anemia | |
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| Hemolytic Anemia | |
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| Pernicious Anemia | |
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| Sickle Cell Anemia | |
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| Leukemia | |
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| Polycythemia Vera | |
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| Hemophilia | |
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| Thrombocytopenia | |
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| Purpura | |
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| Hemolytic Disease of the Newborn | |
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| Diseases of the Heart and Blood Vessels | |
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| Disorders of the Heart | |
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| Congestive Heart Failure | |
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| Hypertrophy and Dilatation | |
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| Myocardial Infarction | |
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| Inflammatory Diseases of the Heart and Blood Vessels | |
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| Endocarditis | |
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| Pericarditis | |
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| Cardiomyopathy | |
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| Valvular Defects | |
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| Rheumatic Heart Disease | |
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| Hypertensive Heart Disease | |
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| Atrial Septal Defect | |
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| Vascular Disorders | |
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| Coronary Artery Disease | |
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| Arteriosclerosis | |
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| Atherosclerosis | |
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| Aneurysm | |
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| Hypertension | |
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| Arteritis | |
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| Takayasu's Arteritis | |
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| Temporal Arteritis | |
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| Phlebitis | |
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| Varicose Veins | |
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| Postmortem Conditions Associated with Diseases of the Heart and Blood Vessels | |
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| Diseases of the Digestive System | |
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| Disorders of the Digestive System | |
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| Gingivitis | |
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| Pharyngitis | |
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| Esophagitis | |
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| Gastritis | |
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| Ulcerative Colitis | |
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| Peptic Ulcers | |
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| Crohn's Disease | |
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| Enteritis | |
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| Colitis | |
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| Appendicitis | |
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| Hemorrhoids | |
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| Hepatitis | |
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| Jaundice | |
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| Cirrhosis | |
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| Cholelithiasis and Cholecystitis | |
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| Cholangitis | |
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| Pancreatitis | |
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| Peritonitis | |
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| Diverticulosis | |
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| Bronze Diabetes | |
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| Hernia | |
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| Stomach Cancer | |
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| Liver Cancer | |
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| Colorectal Cancer | |
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| Polyps | |
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| Obstructions | |
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| Postmortem Conditions Associated with Digestive Disorders | |
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| Diseases of the Respiratory System | |
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| Disorders of the Respiratory System | |
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| Rhinitis and Sinusitis | |
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| Pharyngitis and Laryngitis | |
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| Common Cold | |
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| Tracheitis | |
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| Bronchitis | |
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| Asthma | |
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| Pneumonia | |
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| Pleurisy | |
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| Tuberculosis | |
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| Pneumoconiosis | |
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| Coal Worker's Pneumoconiosis | |
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| Silicosis | |
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| Asbestosis | |
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| Berylliosis | |
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| Atelectasis | |
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| Emphysema | |
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| Lung Abscess | |
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| Fungal Diseases | |
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| Cystic Fibrosis | |
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| Respiratory Polyps | |
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| Carbon Monoxide Poisoning | |
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| Flail Chest | |
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| Lung Cancer | |
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| Chronic Obstructive Pulmonary Disease | |
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| Hanging and Strangulation | |
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| Drowning | |
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| Postmortem Conditions Associated with Respiratory Disorders | |
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| Diseases of the Urinary System | |
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| Disorders of the Urinary System | |
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| Uremia | |
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| Bright's Disease | |
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| Glomerulonephritis | |
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| Urinary Tract Infections | |
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| Pyelitis and Pyelonephritis | |
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| Ureteritis | |
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| Cystitis | |
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| Urethritis | |
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| Hydronephrosis | |
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| Nephrolithiasis | |
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| Polycystic Kidney | |
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| Kidney Malformations | |
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| Renal Cell Carcinoma | |
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| Carcinoma of the Urinary Bladder | |
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| Renal Failure | |
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| Dialysis | |
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| Postmortem Conditions Associated with Urinary Disorders | |
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| Diseases of the Nervous System | |
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| Disorders of the Nervous System | |
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| Meningitis | |
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| Hydrocephalus | |
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| Encephalitis | |
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| Myelitis | |
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| Neuritis | |
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| Epilepsy | |
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| Rabies | |
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| Multiple Sclerosis | |
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| Parkinson's Disease | |
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| Alzheimer's Disease | |
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| Amyotrophic Lateral Sclerosis | |
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| Glioma | |
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| Creutzfeldt-Jakob Disease | |
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| Cerebral Palsy | |
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| Spina Bifida | |
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| Strokes | |
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| Trauma of the Nervous System | |
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| Concussion and Contusion | |
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| Hematoma | |
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| Postmortem Conditions Associated with Nervous Disorders | |
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| Diseases of the Female Reproductive System | |
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| Disorders of the Female Reproductive System | |
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| Pelvic Inflammatory Disease | |
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| Sexually Transmitted Diseases | |
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| Ectopic Pregnancy | |
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| Pre-Eclampsia and Eclampsia | |
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| Endometriosis | |
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| Ovarian Cysts | |
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| Cervical Cancer | |
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| Breast Cancer | |
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| Postmortem Conditions Associated with Female Reproductive System Disorders | |
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| Diseases of the Male Reproductive System | |
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| Disorders of the Male Reproductive System | |
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| Orchitis | |
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| Prostatitis | |
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| Hydrocele | |
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| Cryptorchism | |
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| Inguinal Hernia | |
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| Benign Prostatic Hyperplasia and Prostate Cancer | |
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| Testicular Cancer | |
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| Sexually Transmitted Diseases | |
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| Postmortem Conditions Associated with Male Reproductive System Disorders | |
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| Diseases of the Bones and Joints | |
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| Disorders of the Bones and Joints | |
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| Osteoporosis | |
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| Osteomyelitis | |
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| Osteomalacia and Rickets | |
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| Arthritis | |
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| Osteoarthritis | |
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| Rheumatoid Arthritis | |
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| Psoriatic Arthritis | |
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| Bursitis | |
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| Fractures | |
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| Scoliosis | |
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| Achondroplasia | |
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| Paget's Disease | |
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| Osteosarcoma | |
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| Postmortem Conditions Associated with Diseases of the Bones and Joints | |
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| Diseases of the Endocrine System | |
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| Diseases of the Pancreas | |
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| Diabetes Mellitus | |
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| Cancer of the Pancreas | |
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| Diseases of the Pituitary Gland | |
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| Acromegaly | |
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| Giantism and Dwarfism | |
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| Diabetes Insipidus | |
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| Diseases of the Thyroid Gland | |
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| Gretinism/Myxedema and Hypothyroidism | |
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| Graves' Disease and Hyperthyroidism | |
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| Goiter | |
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| Diseases of the Parathyroid | |
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| Hyperparathyroidism and Hypoparathyroidism | |
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| Diseases of the Adrenal Glands | |
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| Addison's Disease | |
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| Cushing's Syndrome | |
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| Waterhouse-Friderichsen Syndrome | |
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| Postmortem Conditions Associated with Endocrine Gland Disorders | |
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| Diseases of the Integument | |
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| Disorders of the Integument | |
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| Acne | |
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| Abscess | |
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| Syphilis | |
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| Seborrheic Dermatitis | |
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| Psoriasis | |
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| Eczema | |
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| Vitiligo | |
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| Skin Cancer | |
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| Bedsores | |
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| Postmortem Conditions Associated with Disorders of the Integument | |
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| Diseases of the Lymphatic System | |
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| Disorders of the Lymphatic System | |
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| Tonsillitis | |
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| Lymphangitis | |
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| Splenomegaly | |
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| Lymphadenopathy | |
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| Lymphoma | |
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| Postmortem Conditions Associated with Diseases of the Lymphatic System | |
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| Microbiology | |
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| Introduction to Microbiology | |
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| Spontaneous Generation | |
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| Vaccination | |
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| Germ Theory of Disease | |
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| The Magic Bullet | |
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| Naming Microorganisms | |
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| Eukaryotic Cells Versus Prokaryotic Cells | |
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| Kingdoms | |
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| Divisions of Microbiology | |
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| Pathogenic Microorganisms | |
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| Bacteria | |
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| Mycoplasmas | |
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| Rickettsias | |
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| Chlamydia | |
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| Protozoa | |
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| Fungi | |
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| Viruses, Viroids, and Prions | |
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| Anatomy of Bacteria | |
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| Bacteria | |
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| Binary Fission | |
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| Morphology | |
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| Cell Wall Versus Cell Membrane | |
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| Cytoplasm | |
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| Glycocalyx and Capsules | |
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| Motility | |
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| Endospores | |
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| Microscopy | |
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| Fluid Suspensions | |
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| Smearing | |
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| Staining | |
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| Physiology of Bacteria | |
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| Requirements for the Survival of Microorganisms | |
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| Nutrients | |
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| Oxygen | |
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| Moisture Requirements | |
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| Temperature | |
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| pH | |
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| Light | |
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| Osmotic Pressure | |
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| Microbial Associations | |
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| Control of Microorganisms | |
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| Levels of Control | |
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| Physical Methods of Controlling Microorganisms | |
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| Scrubbing | |
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| Temperature | |
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| Incineration | |
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| Cremation | |
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| Dry Heat | |
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| Moist Heat | |
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| Cold | |
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| Light | |
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| Chemical Methods of Controlling Microorganisms | |
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| Factors Influencing Chemical Agents | |
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| Halogens | |
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| Chlorine | |
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| Iodine | |
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| Alcohols | |
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| Aldehydes | |
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| Phenolic Compounds | |
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| Carbolic Acid | |
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| Cresols | |
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| Hexachlorophene | |
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| Quaternary Ammonium Compounds | |
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| Microbe Virulence and Human Resistance | |
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| Factors Influencing the Occurrence of Disease | |
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| Virulence, Resistance, and Infection | |
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| Exogenous and Endogenous Infections | |
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| Communicable Diseases | |
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| Local, Focal, and General Infections | |
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| Primary, Secondary, and Mixed Infections | |
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| Blood Infections | |
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| Factors Influencing the Virulence of Microorganisms | |
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| Sources of the Spread of Disease | |
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| Human Reservoirs | |
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| Universal Precautions | |
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| Nonhuman Animal Reservoirs | |
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| Environmental Reservoirs | |
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| Modes of Transmission of Disease | |
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| Direct Transmission of Infection | |
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| Indirect Contact | |
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| Food and Water | |
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| Air | |
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| Zoonoses | |
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| Vectors | |
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| Portals of Entry and Exit for Pathogens | |
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| Skin and Mucous Membranes | |
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| Respiratory Tract | |
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| Digestive Tract | |
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| Genitourinary Tract | |
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| Placenta | |
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| Vehicles of Exit of Pathogens | |
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| Resistance of the Host Against Infection | |
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| Mechanical Defenses Against Infection | |
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| Physiological Defenses Against Infection | |
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| Chemical Defenses Against Infection | |
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| |
| Lysozyme | |
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| Gastric Juice | |
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| Interferon | |
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| Human Immune System | |
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| Antigens and Antibodies | |
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| Types of Immunity | |
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| Innate Immunity | |
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| Acquired Immunity | |
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| Diseases Caused by Bacteria | |
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| Staphylococci | |
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| |
| Food Poisoning Caused by Staphylococci | |
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| |
| Skin and Wound Infections | |
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| Toxic Shock Syndrome | |
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| Nosocomial Infections | |
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| Streptococcus | |
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| Streptococcus agalactiae | |
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| Pneumococcal Meningitis | |
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| Otitis Media | |
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| Lobar Pneumonia | |
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| Strep Throat | |
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| Impetigo | |
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| Scarlet Fever | |
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| Rheumatic Fever | |
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| Childbirth Fever | |
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| Neisseria gonorrhoeae | |
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| Neisseria meningitidis | |
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| Clostridium | |
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| Botulism | |
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| Food Intoxication | |
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| Tetanus | |
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| Gas Gangrene | |
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| Tissue Gas | |
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| Corynebacteria | |
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| Diphtheria | |
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| Francisella tularensis | |
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| Mycobacterium avium | |
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| Mycobacterium tuberculosis | |
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| Spirochetes | |
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| Leptospira interrogans | |
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| Borrelia burgdorferi | |
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| Treponema pallidum | |
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| Primary Stage | |
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| Secondary Stage | |
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| Tertiary Stage | |
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| Vibrio cholerae | |
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| Bacillus anthracis | |
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| Cutaneous Anthrax | |
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| Inhalation Anthrax | |
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| Gastrointestinal Anthrax | |
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| Bordetella | |
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| Whooping Cough | |
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| DTaP Vaccine | |
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| Enterics | |
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| Escherichia coli | |
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| Klebsiella pneumoniae | |
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| Proteus Species | |
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| Food Infection | |
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| Typhoid Fever | |
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| Shigella Species | |
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| Yersinia pestis | |
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| Haemophilus influenzae | |
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| Gastroenteritis and Stomach Ulcers | |
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| Legionella pneumophilia | |
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| Listeria monocytogenes | |
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| Diseases Caused by Mycoplasmas, Rickettsias, or Chlamydias | |
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| Mycoplasma pneumoniae | |
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| Rickettsia | |
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| Rocky Mountain Spotted Fever | |
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| Typhus | |
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| Q Fever | |
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| Chlamydia | |
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| Chlamydial Pneumonia | |
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| Chlamydia trachomatis | |
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| Parrot Fever | |
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| Diseases Caused by Prions or Viruses | |
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| Prions | |
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| Creutzfeldt-Jakob Disease | |
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| Prion-Suspected Diseases | |
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| Viruses | |
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| Dermatropic (Skin) Diseases | |
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| Smallpox | |
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| Monkeypox | |
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| Measles | |
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| German Measles | |
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| Chickenpox and Shingles | |
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| Herpes | |
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| Cold Sores | |
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| Genital Herpes | |
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| Pneumotropic (Respiratory Tract) Diseases | |
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| Influenza | |
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| Common Cold | |
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| Hantavirus Pulmonary Syndrome | |
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| SARS | |
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| Neurotropic (Central Nervous System) Diseases | |
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| Rabies | |
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| Polio | |
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| Encephalitis | |
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| West Nile | |
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| Viscerotropic (Visceral) Diseases | |
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| Hepatitis | |
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| Hepatitis A | |
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| Hepatitis B | |
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| Hepatitis C | |
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| Mononucleosis | |
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| Inclusion Disease | |
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| Mumps | |
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| Ebola Hemorrhagic Fever | |
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| Immunological Disease | |
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| AIDS | |
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| Diseases of Fungi and Protozoa | |
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| Fungi | |
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| Dermatomycoses | |
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| Coccidioidomycosis | |
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| Histoplasmosis | |
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| Candidiasis | |
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| Fungal Meningitis | |
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| Aspergillosis | |
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| Pneumocystis Pneumonia | |
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| Protozoa | |
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| Amebiasis | |
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| Malaria | |
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| Toxoplasmosis | |
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| African Sleeping Sickness | |
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| East African Sleeping Disease | |
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| West African Sleeping Disease | |
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| Giardiasis | |
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| Cryptosporidiosis | |
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| The Autopsy | |
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| Cellular Anatomy | |
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| Blood | |
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| Anatomy of the Heart and Blood Vessels | |
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| Anatomy of the Digestive System | |
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| Anatomy of the Respiratory System | |
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| Anatomy of the Urinary System | |
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| Anatomy of the Nervous System | |
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| Anatomy of the Female Reproductive System | |
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| Anatomy of the Male Reproductive System | |
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| Anatomy of the Skeletal System | |
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| Anatomy of the Endocrine System | |
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| Anatomy of the Integumentary System | |
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| Anatomy of the Lymphatic System | |
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| Answers to Review Questions | |
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| Glossary | |
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| Index | |