Chemical Synthesis of Nucleoside Analogues

Name: Chemical Synthesis of Nucleoside Analogues
Availability: OutOfStock
ISBN: 9781118007518

ISBN-10: 1118007514

ISBN-13: 9781118007518

Edition: 2013

Authors: Pedro Merino

List price: $200.75

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Description:

Chemical Synthesis of Nucleoside Analogues examines the application of synthetic methodologies to the preparation of compounds of biological interest, including the synthesis of nucleic acids on pre-existing nucleic acid templates, assembling RNA, or DNA. This comprehensive compendium culls expert contributions that highlight the structural components of nucleosides (supported by spectral data) and their modification as well as the synthetic strategies based on chemical approaches. The text serves undergraduate students, specialists, and researchers, allowing access to a variety of compounds without forgetting the biological importance of the target compounds.

Book details

List price: $200.75
Copyright year: 2013
Publisher: John Wiley & Sons, Incorporated
Publication date: 3/25/2013
Binding: Hardcover
Pages: 912
Size: 6.20" wide x 9.30" long x 2.00" tall
Weight: 2.992
Language: English



Contributors


Foreword


Preface



Biocatalytic Methodologies for Selective Modified Nucleosides




Nucleosides Modified at the Base Moiety




Chemical Synthesis of Acyclic Nucleosides




Phosphonated Nucleoside Analogues




Chemical Syntheses of Nucleoside Triphosphates




Mononucleotide Prodrug Synthetic Strategies




Synthesis of C-Nucleosides




Methodologies for the Synthesis of Isomeric Nucleosides and Nucleotides of Antiviral Significance




Synthesis of Conformationally Constrained Nucleoside Analogues




Synthesis of 3'-Spiro-Substituted Nucleosides: Chemistry of TSAO Nucleoside Derivatives




L-Nucleosides




Chemical Synthesis of Carbocyclic Analogues of Nucleosides




Uncommon Three-, Four-, and Six-Membered Nucleosides




Recent Advances in Synthesis and Biological Activity of 4'-Thionucleosides




Recent Advances in the Chemical Synthesis of Aza-Nucleosides




Stereoselective Methods in the Synthesis of Bioactive Oxathiolane and Dioxolane Nucleosides




Isoxazolidinyl Nucleosides




Synthetic Studies on Antifungal Peptidyl Nucleoside Antibiotics




Chemical Synthesis of Conformationally Constrained PNA Monomers



Index