Abbreviations | |
Dedication | p. iii |
About the author | p. iv |
Foreword | p. v |
Preface | p. vii |
Acknowledgments | p. ix |
The Five-Finger Approach to Cardiac Diagnosis | |
The Cardiac History | p. 1 |
Chest Pain or Discomfort | p. 1 |
Coronary Artery Disease (CAD) | p. 1 |
Stable Angina Pectoris, Unstable Angina, and Acute Myocardial Infarction | p. 1 |
Pertinent Past Medical History and/or Risk Factors for CAD | p. 3 |
Chest Pain in Other Cardiovascular Conditions | p. 6 |
Pericarditis | p. 7 |
Aortic Dissection | p. 7 |
Mitral Valve Prolapse | p. 8 |
Left Ventricular Outflow Tract Obstruction (e.g., Valvular Aortic Stenosis, Hypertrophic Cardiomyopathy) | p. 8 |
Pulmonary Hypertension | p. 8 |
Shortness of Breath | p. 9 |
Fatigue and Weakness | p. 12 |
Cough and Hemoptysis | p. 12 |
Palpitations | p. 13 |
Dizziness, Near-Syncope, and Syncope | p. 15 |
Other Symptoms | p. 18 |
Fever, Chills, and Sweats | p. 18 |
Gastrointestinal Symptoms | p. 18 |
Embolic Symptoms | p. 18 |
Intermittent Claudication | p. 18 |
Changes in Weight | p. 18 |
The Cardiac Physical Exam | p. 20 |
Cardiac Anatomy and Physiology | p. 20 |
External Anatomy of the Heart and Great Vessels | p. 20 |
Cardiac Chambers and Blood Flow through the Heart | p. 20 |
The Heart Valves | p. 22 |
Structure of the Heart Wall | p. 22 |
Basic Cardiac Function | p. 23 |
Inspection | p. 23 |
General Appearance | p. 23 |
Cutaneous Manifestations (Skin Color, Temperature, Texture) | p. 27 |
Voice | p. 29 |
Jugular Venous Pressure (JVP) and Pulse | p. 29 |
Estimating JVP | p. 29 |
Abdominojugular Test | p. 31 |
Abnormalities of the Venous Wave Form | p. 31 |
Palpation | p. 33 |
Blood Pressure and Arterial Pulse | p. 33 |
Abnormalities of Blood Pressure | p. 33 |
Abnormalities of Arterial Pulse | p. 36 |
Precordial Movements and Palpation | p. 38 |
Auscultation | p. 44 |
The Cardiac Cycle | p. 44 |
Use of the Stethoscope | p. 47 |
Dynamic Auscultation | p. 52 |
Heart Sounds: Normal and Abnormal | p. 57 |
First and Second heart sounds (S1 and S2) | p. 57 |
Auscultation of S1 ("Lub") | p. 57 |
Loud S1 | p. 57 |
Faint S1 | p. 58 |
Variable Intensity of S1 | p. 58 |
Auscultation of S2 ("Dub") | p. 60 |
Intensity and Splitting of S2 | p. 60 |
Sounds in Systole | p. 61 |
Ejection Sounds and Systolic Clicks | p. 61 |
Sounds in Diastole | p. 62 |
Third and Fourth Heart Sounds (S3 and S4) | p. 62 |
Other Diastolic Sounds | p. 64 |
Heart Murmurs: Systolic, Diastolic, and Continuous | p. 65 |
Systolic Murmurs--Innocent vs Significant ("Guilty") | p. 65 |
Early-mid Systolic (Ejection) Murmurs | p. 68 |
Innocent Murmurs | p. 68 |
Aortic Stenosis | p. 68 |
Pulmonic Stenosis | p. 68 |
Hypertrophic Obstructive Cardiomyopathy | p. 70 |
Atrial Septal Defect | p. 70 |
Holosystolic Murmurs | p. 71 |
Mitral Regurgitation | p. 71 |
Tricuspid Regurgitation | p. 72 |
Ventricular Septal Defect | p. 72 |
Late Systolic Murmurs | p. 73 |
Mitral Valve Prolapse | p. 73 |
Diastolic Murmurs | p. 73 |
Early Diastolic Murmurs | p. 73 |
Aortic Regurgitation | p. 73 |
Pulmonic Regurgitation | p. 75 |
Middiastolic and Presystolic Murmurs | p. 75 |
Mitral Stenosis | p. 75 |
Tricuspid Stenosis | p. 76 |
Continuous Murmurs | p. 76 |
Patent Ductus Arteriosus | p. 77 |
Jugular Venous Hum | p. 76 |
Coronary Arteriovenous Fistula | p. 76 |
Pulmonary Arteriovenous Fistula | p. 76 |
Ruptured Sinus of Valsalva Aneurysm | p. 77 |
Miscellaneous | p. 78 |
Pericardial Friction Rubs | p. 78 |
Electrocardiogram | p. 79 |
Basic Electrocardiography | p. 79 |
Cardiac Electrical Activity and the Electrocardiogram (ECG) | p. 79 |
Standard ECG Leads | p. 79 |
Approach to ECG Interpretation | p. 80 |
Rate and Rhythm | p. 84 |
The P Wave | p. 86 |
The QRS | p. 86 |
The T Wave | p. 88 |
The U Wave | p. 88 |
The PR Interval | p. 89 |
The ST Segment | p. 89 |
The QT Interval | p. 91 |
QRS Axis | p. 91 |
Major ECG Abnormalities: Diagnostic Clues and Clinical Correlations | p. 92 |
Myocardial Ischemia and Infarction | p. 92 |
Cardiac Chamber Enlargement and Hypertrophy | p. 100 |
Miscellaneous Patterns | p. 104 |
Arrhythmias and Conduction Disturbances | p. 105 |
Chest X-Ray | p. 120 |
The Cardiovascular Silhouette, Cardiac Chambers and the Aorta | p. 120 |
The Pulmonary Vasculature | p. 124 |
The Lung Fields | p. 126 |
Thoracic Cage Abnormalities | p. 126 |
Cardiac Diagnostic Laboratory Tests | p. 128 |
Blood Tests | p. 128 |
Routine Chemistries | p. 128 |
Cardiac Enzymes | p. 130 |
Specialized Non-invasive Tests | p. 131 |
Transthoracic M-Mode and Two Dimensional Color-Flow Doppler Echocardiograpy | p. 131 |
Transesophageal Echocardiography | p. 134 |
Ambulatory Electrocardiography; Holter Monitoring and Transtelephonic ECG/Event Recording | p. 136 |
Signal Averaged Electrocardiography | p. 137 |
Tilt-Table Testing | p. 138 |
Exercise and Pharmacologic Stress Testing, including Nuclear and Echocardiographic Imaging | p. 139 |
Radionuclide Studies | p. 144 |
Electron Beam Computed Tomography | p. 145 |
Specialized Invasive Techniques | p. 146 |
Cardiac Catheterization: Coronary Angiography and Left Ventriculography | p. 146 |
Electrophysiologic Studies (EPS) | p. 152 |
Summary: Non-invasive and Invasive Test Indications and Applications | p. 153 |
Cardiovascular Therapy | |
General Considerations in Cardiovascular Therapy | p. 157 |
Cardiac Drugs | p. 161 |
Beta blockers | p. 161 |
Calcium Channel Blockers | p. 163 |
Nitrates | p. 164 |
Angiotensin-Converting Enzyme (ACE) Inhibitors | p. 165 |
Angiotensin Receptor Blockers (ARBs) | p. 167 |
Inotropic Agents | p. 167 |
Digitalis Glycosides | p. 167 |
Sympathomimetic Amines | p. 168 |
Phosphodiesterase Inhibitors | p. 168 |
Diuretics | p. 169 |
Thiazides | p. 169 |
Loop Diuretics | p. 169 |
Potassium Sparing Diuretics | p. 169 |
Antiplatelet Agents | p. 170 |
Aspirin | p. 170 |
Thienopyridines | p. 171 |
Glycoprotein II b/III a Receptor Inhibitors | p. 171 |
Thrombolytics and Anticoagulants | p. 172 |
Thrombolytic Agents | p. 172 |
Unfractionated and Low Molecular Weight Heparin | p. 173 |
Warfarin (Coumadin) | p. 174 |
Lipid Controlling Agents | p. 175 |
HMG CoA Reductase Inhibitors (Statins) | p. 175 |
Nicotinic Acid (Niacin) | p. 176 |
Bile Acid Sequestrants (Resins) | p. 177 |
Fibric Acid Derivatives (Fibrates) | p. 177 |
Other Agents (e.g., Ezetimibe) | p. 177 |
Antiarrhythmic Agents | p. 177 |
Class I Agents | p. 179 |
Class II Agents | p. 181 |
Class III Agents | p. 181 |
Class IV Agents | p. 182 |
Other Agents (e.g., Digitalis, Adenosine) | p. 182 |
Cardiac Nonpharmacologic and Interventional Techniques | p. 184 |
Percutaneous Coronary Intervention (PCI): Percutaneous Transluminal Coronary Angioplasty (PTCA) and Stenting | p. 184 |
Transluminal Balloon Valvuloplasty | p. 186 |
Radiofrequency Catheter Ablation | p. 187 |
Electrical Cardioversion and Defibrillation | p. 188 |
Cardiac Device Therapy | p. 190 |
Cardiac Pacemakers | p. 190 |
Implantable Cardioverter Defibrillator | p. 192 |
Cardiac Surgery | p. 195 |
Coronary Artery Bypass Grafting | p. 195 |
Valvular Repair and/or Replacement | p. 195 |
Cardiac Transplantation | p. 197 |
Putting It All Together | |
Approach to the Patient with Coronary Artery Disease | p. 199 |
Angina Pectoris | p. 202 |
Clinical Recognition of Stable Angina Pectoris | p. 202 |
Clinical Recognition of Unstable Angina | p. 205 |
Management of Stable Angina Pectoris | p. 206 |
Management of Unstable Angina | p. 207 |
Acute Myocardial Infarction (MI) | p. 209 |
Clinical Recognition of Acute MI | p. 210 |
Management of Acute MI | p. 217 |
Complications of Acute MI | p. 225 |
Electrical Complications of Acute MI | p. 225 |
Ventricular Arrhythmias | p. 226 |
Supraventricular Arrhythmias | p. 226 |
Bradyarrhythmias and Conduction Disturbances | p. 226 |
Mechanical Complications of Acute MI | p. 228 |
Left Ventricular (LV) Systolic Dysfunction | p. 228 |
Acute Ventricular Septal Defect and Papillary Muscle Rupture | p. 229 |
Right Ventricular Infarction | p. 230 |
Left Ventricular Aneurysm | p. 231 |
LV Free Wall Rupture and Pseudoaneurysm | p. 232 |
Pericarditis | p. 232 |
Secondary Prevention: Pharmacologic Therapy, Risk Factor Modification and Cardiac Rehabilitation | p. 233 |
Approach to the Patient with Heart Failure | p. 235 |
Etiology and Pathophysiology | p. 235 |
Left Ventricular Systolic Dysfunction | p. 235 |
Dilated Cardiomyopathy | p. 239 |
Left Ventricular Diastolic Dysfunction | p. 243 |
Treatment of Chronic Heart Failure | p. 245 |
Treatment of Acute Pulmonary Edema | p. 247 |
Approach to the Patient with Systemic Arterial Hyertension | p. 249 |
Primary and Secondary Forms of Hypertension | p. 249 |
Clinical Manifestations of Hypertension | p. 249 |
Therapy of Hypertension | p. 252 |
Approach to the Patient with Dyslipidemia | p. 259 |
Pathogenesis of Atherosclerosis | p. 259 |
Therapeutic Considerations | p. 259 |
Approach to the Patient with Valvular Heart Disease | p. 262 |
Aortic Stenosis (AS) | p. 262 |
Clinical Recognition of AS | p. 262 |
Management of AS | p. 266 |
Aortic Regurgitation (AR) | p. 268 |
Chronic AR | p. 268 |
Clinical Recognition of Chronic AR | p. 268 |
Acute AR | p. 269 |
Clinical Recognition of Acute AR | p. 269 |
Management of Chronic and Acute AR | p. 269 |
Mitral Regurgitation (MR) | p. 271 |
Chronic MR | p. 271 |
Clinical Recognition of Chronic MR | p. 271 |
Management of Chronic MR | p. 272 |
Acute MR | p. 274 |
Clinical Recognition and Management of Acute MR | p. 274 |
Mitral Valve Prolapse (MVP) | p. 274 |
Clinical Recognition of MVP | p. 274 |
Management of MVP | p. 275 |
Rheumatic Mitral Stenosis (MS) | p. 275 |
Clinical Recognition of Rheumatic MS | p. 275 |
Management of Rheumatic MS | p. 279 |
Tricuspid Regurgitation (TR) | p. 280 |
Clinical Recognition of TR | p. 280 |
Management of TR | p. 280 |
Approach to the Patient with Hypertrophic Cardiomyopathy | p. 281 |
Clinical Recognition of Hypertrophic Obstructive Cardiomyopathy (HOCM) | p. 281 |
Treatment Options for HOCM | p. 283 |
Risk of Sudden Death | p. 284 |
Approach to the Patient with Infective Endocarditis | p. 285 |
Etiology and Risk Factors | p. 285 |
Clinical Presentation of Infective Endocarditis | p. 285 |
Therapy of Infective Endocarditis | p. 287 |
Approach to the Patient with Aortic Dissection | p. 291 |
Classification and Pathogenesis | p. 291 |
Clinical Manifestations of Aortic Dissection | p. 292 |
Medical and Surgical Considerations in Aortic Dissection | p. 293 |
Approach to the Patient with Pericardial Disease | p. 294 |
Acute Pericarditis | p. 294 |
Cardiac Tamponade | p. 295 |
Constrictive Pericarditis | p. 297 |
Approach to the Patient with Pulmonary Hypertension | p. 300 |
Pathophysiologic Mechanisms | p. 300 |
Clinical Recognition of Primary Pulmonary Hypertension | p. 300 |
Management of Primary Pulmonary Hypertension | p. 301 |
Approach to the Patient with a Heart Murmur | p. 303 |
When to Order a Doppler-Echo | p. 303 |
Approach to the Patient with Cardiac Arrhythmias and Conduction Disturbances | p. 308 |
General Considerations | p. 308 |
Atrial Fibrillation | p. 311 |
Supraventricular Tachycardias | p. 315 |
Ventricular Tachycardia | p. 316 |
Bradyarrhythmias and Conduction Abnormalities | p. 318 |
Approach to the Patient with Adult Congenital Heart Disease | p. 319 |
Bicuspid Aortic Valve | p. 319 |
Pulmonic Valve Stenosis | p. 319 |
Atrial Septal Defect | p. 321 |
Ventricular Septal Defect | p. 321 |
Coarctation of the Aorta | p. 322 |
Patent Ductus Arteriosus | p. 324 |
Marfan's Syndrome | p. 324 |
Approach to the Patient with Heart Disease Undergoing Noncardiac Surgery | p. 325 |
Preoperative Assessment of Risk | p. 325 |
Clinical Predictors of Risk | p. 325 |
Surgery Specific Markers of Risk | p. 326 |
Perioperative Evaluation and Management | p. 327 |
Approach to the Patient with Neoplastic Heart Disease | p. 328 |
Primary Tumors of the Heart | p. 328 |
Atrial Myxoma | p. 328 |
Angiosarcoma | p. 329 |
Secondary Tumors of the Heart and the Effects of Treatment | p. 329 |
Carcinoid Syndrome | p. 329 |
Approach to the Patient with "False" Heart Disease | p. 331 |
Pitfalls in the Clinical Recognition and Management of Heart Disease | p. 331 |
Misleading Clues in the Clinical Cardiovascular Evaluation | p. 331 |
Misinterpretation of Symptoms and Signs | p. 331 |
Misinterpretation of ECG, CXR, and Diagnostic Laboratory Data | p. 332 |
The Athlete's Heart | p. 335 |
Iatrogenic Heart Disease | p. 337 |
Approach to the Patient with an Acute Cardiac Emergency | p. 338 |
General Considerations | p. 338 |
Universal Approach to Adult Emergency Cardiac Care | p. 339 |
Ventricular Fibrillation/Pulseless Ventricular Tachycardia | p. 340 |
Pulseless Electrical Activity | p. 340 |
Asystole | p. 341 |
Bradycardia | p. 341 |
Tachycardia | p. 342 |
Shock | p. 343 |
Selected Reading | p. 344 |
Index | p. 347 |
Table of Contents provided by Rittenhouse. All Rights Reserved. |