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About the Authors | |
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Preface | |
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Introduction to Geriatric Psychopharmacology | |
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Pharmacokinetics and Aging | |
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Absorption | |
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Distribution | |
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Metabolism | |
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Protein Binding | |
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Clearance | |
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Drug Half-Life | |
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Pharmacodynamics and Aging | |
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The Practice of Geriatric Psychopharmacology | |
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Maximizing Therapeutic Effects | |
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Improving Compliance | |
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Minimizing Adverse Effects | |
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Containing Costs | |
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Summary Guidelines: The Practice of Geriatric Psychopharmacology | |
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Chapter Summary | |
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References | |
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Major Psychotropic Drug Classes | |
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Antipsychotics | |
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Pharmacokinetics | |
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Pharmacodynamics and Mechanism of Action | |
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Drug Interactions | |
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Indications | |
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Efficacy | |
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Clinical Use | |
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Choice of Antipsychotic | |
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Alternative Formulations | |
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Baseline Laboratory Studies | |
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Dose and Dose Titration | |
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PRN Use of Antipsychotics | |
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Monitoring Treatment | |
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Serum Antipsychotic Levels | |
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Managing Treatment Resistance | |
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Switching Antipsychotics | |
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Adjunctive Treatments | |
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Discontinuation of Antipsychotics | |
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Antipsychotic Overdose in Elderly Patients | |
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Side Effects | |
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Treatment of Selected Syndromes and Disorders With Antipsychotics | |
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Delirium | |
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Delusional Disorder | |
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Dementia With Psychotic Symptoms | |
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Depression With Psychotic Symptoms | |
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Mania | |
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Parkinson's Disease With Psychosis | |
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Personality Disorders | |
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Schizoaffective Disorder | |
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Schizophrenia | |
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Secondary Psychotic Syndromes | |
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Substance Intoxication and Withdrawal | |
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Chapter Summary | |
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References | |
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Antipsychotics: Specific Drugs | |
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Antidepressants | |
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Pharmacokinetics | |
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Pharmacodynamics and Mechanism of Action | |
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Drug Interactions | |
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Efficacy | |
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Clinical Use | |
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Choice of Antidepressant | |
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Alternative Formulations | |
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Baseline Laboratory Studies and Clinical Evaluation | |
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Dose and Dose Titration | |
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Course of Antidepressant Response | |
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Monitoring Antidepressant Therapy | |
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Duration of Treatment | |
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Managing Treatment Resistance | |
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Discontinuation of Antidepressants | |
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Antidepressant Overdose | |
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Side Effects | |
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Overview of Side Effects by Medication Class | |
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System-Specific Side Effects | |
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Treatment of Selected Syndromes and Disorders With Antidepressants | |
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Anxiety Disorders | |
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Depressive Disorders | |
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Chapter Summary | |
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References | |
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Antidepressants: Specific Drugs | |
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Mood Stabilizers | |
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Pharmacokinetics | |
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Pharmacodynamics and Mechanism of Action | |
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Drug Interactions | |
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Efficacy | |
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Clinical Use | |
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Choice of Drug | |
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Alternative Formulations | |
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Baseline Laboratory Studies and Clinical Evaluation | |
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Dose and Dose Titration | |
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Course of Response | |
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Monitoring Treatment | |
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Duration of Treatment | |
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Managing Treatment Resistance | |
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Discontinuation of Mood Stabilizers | |
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Overdose/Overmedication | |
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Side Effects | |
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Side Effects of Specific Agents | |
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System-Specific Side Effects | |
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Treatment of Selected Syndromes and Disorders With Mood Stabilizers | |
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Aggression in Dementia | |
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Alcohol/Sedative Withdrawal | |
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Bipolar Depression | |
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Bipolar Mania | |
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Bipolar Mixed State | |
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Bipolar Disorder Prophylaxis | |
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Pain Syndromes | |
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Personality Disorders | |
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Posttraumatic Stress Disorder | |
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Rapid Cycling | |
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Restless Legs Syndrome | |
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Schizoaffective Disorder | |
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Secondary Mania | |
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Unipolar Depression | |
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Chapter Summary | |
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References | |
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Mood Stabilizers: Specific Drugs | |
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Anxiolytic and Sedative-Hypnotic Medications | |
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Pharmacokinetics | |
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Pharmacodynamics and Mechanism of Action | |
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Drug Interactions | |
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Indications | |
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Efficacy | |
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Clinical Use | |
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Nonpharmacological Therapies | |
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Choice of Drug | |
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Patient Education | |
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Baseline Laboratory and Diagnostic Studies | |
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Dose and Dose Titration | |
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Duration of Treatment | |
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Monitoring Treatment | |
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Management of Nonresponse | |
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Switching Drugs | |
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Overdose | |
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Tolerance and Abuse | |
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Dependence, Discontinuation, and Withdrawal Syndromes | |
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Side Effects | |
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Treatment of Selected Syndromes and Disorders With Anxiolytics and Sedative-Hypnotics | |
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Anxiety Disorders | |
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Sleep Disorders | |
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Other Disorders | |
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Chapter Summary | |
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References | |
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Anxiolytics and Sedative-Hypnotics: Specific Drugs | |
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Treatment of Other Geriatric Syndromes and Disorders | |
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Treatment of Substance-Related Disorders | |
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Substance Use Disorders | |
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Diagnosis of Abuse and Dependence | |
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Treatment | |
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Substance-Induced Disorders | |
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Alcohol-Related Syndromes | |
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Chapter Summary | |
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References | |
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Treatment of Movement Disorders | |
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Movement Abnormalities | |
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Akinesia and Bradykinesia | |
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Athetosis | |
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Chorea | |
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Dystonia | |
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Hemiballismus | |
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Myoclonus | |
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Rigidity | |
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Tics | |
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Tremor | |
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Treatment of Selected Movement Disorders | |
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Degenerative Disorders | |
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Drug-Induced Syndromes | |
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Other Movement Abnormalities | |
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Chapter Summary | |
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References | |
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Treatment of Dementias and Other Cognitive Syndromes | |
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Evaluation of the Cognitively Impaired Elder | |
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Treatment of Specific Cognitive Disorders | |
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Alcohol-Related Dementia (Alcohol-Induced Persisting Dementia) | |
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Alzheimer's Disease | |
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Amnestic Disorder | |
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Delirium | |
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Dementia of Depression | |
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Frontotemporal Dementia (Frontal Lobe Dementia) | |
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Dementia With Lewy Bodies (Lewy Body Dementia) | |
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Mental Retardation | |
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Mild Cognitive Dysfunction | |
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Parkinson's Disease With Dementia | |
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Schizophrenia-Related Cognitive Dysfunction | |
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Vascular Dementia | |
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Treatment of Behavioral Disturbances in Dementia | |
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Agitation and Aggression | |
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Hypersexuality and Inappropriate Sexual Behaviors | |
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Sundowning | |
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Chapter Summary | |
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References | |
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Dementias and Other Cognitive Syndromes: Specific Drugs | |
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Index | |