Section Editors | |
Contributing Authors | |
Preface | |
Acknowledgments | |
Overview | p. 1 |
The History of Ocular Pharmacology | p. 3 |
Pharmacodynamics: Drug-Receptor Interactions | p. 9 |
Drug Reactions Not Mediated via Receptors | p. 35 |
Cholinergics | p. 41 |
Eicosanoid Receptors in Ocular Tissues | p. 51 |
Steroids in Ocular Therapy | p. 61 |
Adrenergic Pharmacology of the Anterior Segment | p. 75 |
Immunosuppressive Therapy for Uveitis | p. 95 |
Ocular Pharmacokinetics | p. 119 |
Basic Considerations of Ocular Drug-Delivery Systems | p. 139 |
Development of New Drugs for Ophthalmology | p. 151 |
Ethical Issues in Ophthalmic Research | p. 165 |
The Ophthalmologist as Clinical Investigator | p. 171 |
Introduction to Toxicology | p. 179 |
Effect of Disease on Drug Disposition | p. 187 |
Effect of Age on Drug Disposition | p. 197 |
Effect of Pregnancy on Drug Disposition | p. 205 |
Overview | p. 217 |
Definitions and Classification of Glaucoma | p. 219 |
Direct, Indirect, and Dual-Action Parasympathetic Drugs | p. 221 |
Epinephrine and Dipivefrin | p. 239 |
Alpha-2 Agonists in Glaucoma Therapy | p. 247 |
Thymoxamine (Alpha-Adrenergic Antagonist) | p. 255 |
Beta-blockers | p. 261 |
Oral Carbonic Anhydrase Inhibitors | p. 277 |
Topical Carbonic Anhydrase Inhibitors | p. 287 |
Hyperosmotic Agents | p. 291 |
Antifibrosis Agents: Pharmacologic Inhibition of Wound Healing | p. 297 |
Prostaglandins and Prostaglandin Analogues | p. 315 |
Future Role of Neuroprotective Agents in Glaucoma | p. 329 |
Medical Trabeculocanulotomy | p. 341 |
Physiologic Aspects of Glaucoma and Its Current and Future Management | p. 347 |
Overview | p. 361 |
Antibiotics and Antifungals | p. 363 |
Antivirals in the Treatment of Retinal Diseases | p. 387 |
Pharmacologic Therapy for Cystoid Macular Edema | p. 409 |
Proliferative Vitreoretinopathy: Biology and Pharmacology | p. 417 |
Drugs Affecting the Coagulation/Fibrinolysis Pathways | p. 429 |
Ocular Pharmacology of Diabetic Retinopathy | p. 443 |
Medical Therapy for Macular Degeneration | p. 447 |
Angiogenesis and Growth Factors | p. 455 |
Overview | p. 471 |
Penicillins and Cephalosporins | p. 473 |
Antiparasitic Agents | p. 493 |
The Tetracyclines | p. 507 |
Erythromycin, Clarithromycin, and Azithromycin | p. 515 |
Chloramphenicol | p. 525 |
Aminoglycosides in Ophthalmology | p. 531 |
Fluoroquinolones | p. 537 |
Peptide Antibiotics: Vancomycin, Bacitracin, and Polymyxin B | p. 549 |
Rifampin | p. 559 |
Amebic Disease of the Eye | p. 565 |
Antivirals | p. 575 |
Pharmacotherapy of Fungus Infections of the Eye | p. 587 |
Antiallergic Therapies | p. 609 |
Intraocular Irrigating Solutions | p. 635 |
Surgical Viscoelastic Substances | p. 655 |
Antiseptics and Disinfectants | p. 661 |
Mitomycin Treatment of Corneal Disease | p. 667 |
Cyanoacrylate Tissue Adhesives | p. 671 |
Future Developments in Corneal Therapy: Growth Factors | p. 675 |
Overview | p. 681 |
Pharmacology of Medical Therapy for Uveitis | p. 683 |
Mydriatic and Cycloplegic Agents | p. 703 |
Nonsteroidal Antiinflammatory Drugs | p. 713 |
Immunosuppressive Chemotherapy | p. 723 |
Overview | p. 763 |
Anesthetic and Perianesthetic Medications | p. 765 |
Anesthetic Considerations for Ophthalmic Surgery | p. 771 |
Overview | p. 781 |
Topical Ophthalmic Preparations Used for Infants and Children | p. 783 |
Cycloplegic Agents | p. 787 |
Topical and Local Anesthetic Agents | p. 791 |
Antiglaucoma Medications | p. 795 |
Ocular Antiinflammatory Agents | p. 801 |
Overview | p. 805 |
Mydriatic and Cycloplegic Drugs | p. 807 |
Drugs for the Diagnosis of Pupillary Disorders | p. 827 |
Drugs for the Diagnosis and Treatment of Myasthenia Gravis | p. 837 |
Sodium Fluorescein and Other Tissue Dyes | p. 849 |
Subject Index | p. 865 |
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