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| List of Cases | |
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| List of Laboratory Techniques | |
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| Preface | |
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| About the Author | |
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| Functions of the Immune System and Immunity | |
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| An Overview of the Immune System | |
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| Historical Perspective | |
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| An Introduction to the Immune System | |
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| Overview of Innate and Adaptive Immune Integration | |
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| Immunodeficiencies | |
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| Antigens and Antigen Recognition | |
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| Antigens | |
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| Activators of Lymphocytes | |
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| Antigen Recognition | |
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| Antibodies | |
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| Antibodies | |
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| Antigen Antibody Interactions | |
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| Classification of Antibodies | |
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| Properties and Biological Functions of Antibody Isotypes | |
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| Quantitation of Serum Antibodies | |
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| Monoclonal Antibodies | |
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| Cells and Tissues of Innate Immunity | |
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| Lymphoid Tissues | |
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| Cells of Innate Immunity | |
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| Assessing Dysfunction in Phagocytes and Natural Killer Cells | |
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| Separation of Cell Populations | |
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| B cells | |
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| B cells | |
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| B cell Maturation | |
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| Naive B cell Activation Following Antigen Encounter | |
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| Secondary Immune Responses | |
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| B cell Responses to T-Independent Antigens | |
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| B cell Responses to Polyclonal Activators | |
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| B cell Enumeration and B cell Function | |
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| The Major Histocompatibility Complex, Antigen Processing, and Antigen Presentation | |
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| Recognition of Non-Self | |
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| Major Histocompatibility Complex | |
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| MHC Genes and Disease | |
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| Transplantation | |
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| Antigen Processing and Antigen Presentation | |
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| T cells | |
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| T cells | |
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| General Features of T cell Receptors | |
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| T cell Maturation | |
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| CD4+ T cells Encounter Antigen | |
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| CD8+ T cells Encounter Antigen | |
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| Memory T cells | |
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| Enumeration of T cells | |
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| Approaches for the Isolation of T cells | |
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| Assessing T cell Function | |
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| Complement | |
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| Complement | |
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| Classical Pathway of Complement | |
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| Alternative Pathway of Complement | |
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| Regulation of Complement | |
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| Complement Receptors | |
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| Biological Activities of Complement | |
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| Complement Deficiencies and Disease | |
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| Evaluating Complement Pathways | |
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| Orchestration of Host Defenses in Response to Infection | |
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| Orchestration of Host Defenses in Response to Infection | |
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| Infectious Agents Outside Cells: Extracellular Microbes | |
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| Microbes That Thrive in the Phagosomes | |
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| Microbes Present in the Cell Cytosol | |
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| Laboratory Techniques | |
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| Instrumentation | |
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| Instrumentation for Measurement of Antigen-Antibody Interactions | |
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| Instrumentation for Measuring Color Intensity | |
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| Instrumentation for Measuring Chemiluminescence | |
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| Instrumentation for Measuring Fluorescence | |
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| Instrumentation for Detecting Radioactivity | |
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| Instrumentation for Detecting Non-labeled Immune Complexes | |
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| Indicator Labels | |
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| Indicator-labeled Immunoassays | |
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| Methods of Coupling Indicator Labels to Antigens or Antibodies | |
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| Standard Curves in Immunoassays | |
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| Principles of Immunoassays That Use Indicator Labels | |
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| Indicator-labeled Immunoassays: Nomenclature | |
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| Precipitation | |
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| Antigen and Antibody Interactions | |
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| The Precipitin Curve | |
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| Immunodiffusion | |
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| Immunodiffusion Techniques | |
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| Single Immunodiffusion Techniques | |
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| Double Immunodiffusion Techniques | |
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| Electrophoresis | |
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| Electrophoresis | |
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| Factors That Influence the Rate of Protein Migration | |
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| Non Soluble Support Mediums | |
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| Zone Electrophoresis | |
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| Two-Stage Approach to Immunoelectrophoresis | |
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| One-Stage Approach to Immunoelectrophoresis | |
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| Polyacrylamide Gel Electrophoresis | |
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| Agglutination | |
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| Agglutination | |
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| Principles of Agglutination | |
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| Agglutination Techniques | |
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| Types of Agglutination Reactions | |
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| Antiglobulins Tests | |
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| Applications of the Agglutination/Hemagglutination Reaction | |
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| Molecular Diagnostic Technology | |
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| Molecular Diagnostic Technology | |
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| Nucleic Acids | |
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| Molecular Biology Tools | |
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| Amplification of Nucleic Acids | |
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| Signal Amplification Assays | |
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| Capture and Detection Techniques | |
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| Molecular Blotting Techniques | |
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| Detecting Genetic Mutations in Clinical Laboratories | |
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| Diseases and Disorders | |
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| Bacterial Infections in Sexually Transmitted Diseases | |
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| Venereal Syphilis: Treponema pallidum | |
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| Laboratory Diagnosis | |
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| Gonorrhoea: Neisseria gonorrhoeae | |
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| Laboratory Diagnosis | |
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| Genital Tract Infection: Chlamydia trachomatis | |
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| Laboratory Diagnosis | |
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| Upper Respiratory Tract Bacterial Infections | |
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| Atypical Pneumonia: Mycoplasma pneumoniae | |
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| Streptococcal Infections: Streptoccaceae | |
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| Whooping Cough: Bordetella pertussis | |
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| Bacterial Infections: Tick Borne, Enteric, and Zoonotic | |
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| Lyme Disease: Borrelia burgdorferi | |
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| Rocky Mountain Spotted Fever: Rickettsia rickettsii | |
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| Leptospirosis: Leptospira interrogans | |
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| Salmonellosis and Typhoid Fever: Salmonella species | |
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| Hepatitis | |
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| The Causative Agents of Hepatitis | |
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| Clinical Manifestations/Pathology | |
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| Immunology of Hepatitis Infections | |
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| Immunization | |
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| Laboratory Diagnosis | |
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| Measles, Mumps, Rubella, and Varicella | |
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| Measles | |
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| Mumps | |
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| Rubella | |
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| Varicella | |
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| Viruses III | |
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| Adenovirus | |
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| Cytomegalovirus | |
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| Epstein Barr Virus | |
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| Influenza Virus | |
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| Polio | |
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| Retroviral Infections | |
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| General Features of Retroviruses | |
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| HIV | |
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| Human T cell Leukemia Virus | |
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| Fungal Infections | |
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| Aspergillus fumigatus | |
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| Candida albicans | |
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| Cryptococcus neoformans | |
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| Parasitic Infections | |
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| Amebic Infections | |
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| Echinococcosis: Echinococcus granulosus | |
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| Malaria | |
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| Toxoplasma gondii | |
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| Autoimmune Disorders | |
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| Autoimmunity | |
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| Diabetes Mellitus | |
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| Rheumatoid Arthritis | |
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| Systemic Lupus Erythematosus | |
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| Graves' Disease | |
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| Hashimoto's Thyroiditis | |
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| Pernicious Anemia | |
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| Tumor Immunology | |
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| Tumor Immunology | |
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| Tumor Antigens | |
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| Immunological Responses to Tumors | |
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| Mechanisms by Which Tumors Evade the Immune System | |
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| Myeloid and Lymphoid Neoplasms | |
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| Immunodeficiency Disorders | |
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| Primary Immunodeficiency Disorders | |
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| Secondary Immunodeficiency Disorders | |
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| Laboratory Tests | |
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| Hypersensitivity | |
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| Hypersensitivity | |
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| Type I Hypersensitivity Reactions | |
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| Type II Hypersensitivity Reactions | |
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| Type III Hypersensitivity Reactions | |
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| Type IV Hypersensitivity Reactions | |
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| Laboratory Testing for IgE Antibodies | |
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| Laboratory Biosafety | |
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| DNA and RNA Viruses | |
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| Textbook References | |
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| Immunology References | |
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| Vaccine References | |
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| Laboratory Techniques References | |
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| List of Journals | |
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| List of Web Sites | |
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| Conferences | |
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| Glossary | |
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| Index | |