| |
| |
| Preface to the Third Edition | |
| |
| |
| Preface to the Second Edition | |
| |
| |
| Preface to the First Edition | |
| |
| |
| Acknowledgments | |
| |
| |
| |
| Dementia: Significance, Definition, and Epidemiology | |
| |
| |
| Significance | |
| |
| |
| Definition of Dementia | |
| |
| |
| Prevalence of Different Dementing Diseases | |
| |
| |
| Summary | |
| |
| |
| |
| Mental Status Assessment | |
| |
| |
| Clinical History | |
| |
| |
| Mental Status Examination | |
| |
| |
| Behavioral Rating Scales | |
| |
| |
| Standardized Neuropsychological Tests | |
| |
| |
| Summary | |
| |
| |
| |
| Diagnosis of Dementia | |
| |
| |
| Normal Aging versus Dementia | |
| |
| |
| Age-Associated Cognitive Impairments | |
| |
| |
| Mild Cognitive Impairment | |
| |
| |
| Amnesia versus Dementia | |
| |
| |
| Delirium versus Dementia | |
| |
| |
| Aphasia versus Dementia | |
| |
| |
| Differential Diagnosis of Dementing Diseases | |
| |
| |
| Examples of Differential Diagnosis | |
| |
| |
| |
| Alzheimer's Disease | |
| |
| |
| Clinical Characteristics | |
| |
| |
| Disease Course | |
| |
| |
| Laboratory Investigation | |
| |
| |
| Neuropathology | |
| |
| |
| Risk Factors and Etiology | |
| |
| |
| Proposed Pathophysiologic Mechanisms | |
| |
| |
| Prevention and Treatment | |
| |
| |
| |
| Vascular Dementia | |
| |
| |
| Clinical Criteria for Vascular Dementia | |
| |
| |
| Classification and Characteristics of Vascular Dementia | |
| |
| |
| Differential Diagnosis | |
| |
| |
| Disease Course | |
| |
| |
| Laboratory Investigation | |
| |
| |
| Pathology and Pathophysiology | |
| |
| |
| Risk Factors | |
| |
| |
| Treatment | |
| |
| |
| |
| Frontotemporal Dementia and the Asymmetric Cortical Atrophies | |
| |
| |
| Frontotemporal Lobar Degeneration | |
| |
| |
| Frontotemporal Dementia | |
| |
| |
| Asymmetric Cortical Atrophies | |
| |
| |
| |
| Parkinsonian Disorders with Dementia | |
| |
| |
| Dementia with Lewy Bodies | |
| |
| |
| Parkinson's Disease with Dementia | |
| |
| |
| Progressive Supranuclear Palsy | |
| |
| |
| Corticobasal Degeneration | |
| |
| |
| Multiple System Atrophy | |
| |
| |
| Heredodegenerative Diseases with Parkinsonism | |
| |
| |
| Secondary Parkinsonism | |
| |
| |
| |
| Nonparkinsonian Motor Disorders with Dementia | |
| |
| |
| Huntington's Disease | |
| |
| |
| Wilson's Disease | |
| |
| |
| Hallervorden-Spatz Disease | |
| |
| |
| Amyotrophic Lateral Sclerosis/Parkinson's Dementia Complex | |
| |
| |
| Motor Neuron Disease with Dementia | |
| |
| |
| Hereditary Spinocerebellar Ataxias | |
| |
| |
| Dementia with Other Motor Disorders | |
| |
| |
| |
| Dementia from Conventional Infectious Agents | |
| |
| |
| HIV-Associated Dementia | |
| |
| |
| Neurosyphilis | |
| |
| |
| Lyme Disease | |
| |
| |
| Whipple's Disease | |
| |
| |
| Non-HIV Causes of Viral Encephalitis | |
| |
| |
| Other Bacterial and Fungal Causes of Meningitis | |
| |
| |
| Parasitic Diseases | |
| |
| |
| |
| Creutzfeldt-Jakob Disease and Other Prion Disorders | |
| |
| |
| Creutzfeldt-Jakob Disease | |
| |
| |
| Other Prion Dementias | |
| |
| |
| |
| Toxic-Metabolic Causes of Dementia | |
| |
| |
| Toxic Dementias | |
| |
| |
| Acquired Metabolic Disorders | |
| |
| |
| Inherited Metabolic Disorders | |
| |
| |
| |
| Psychiatric Dementias Associated with Psychiatric Disorders | |
| |
| |
| Depression-Associated Dementia | |
| |
| |
| Mania-Associated Dementia | |
| |
| |
| Schizophrenia-Associated Dementia | |
| |
| |
| "Pseudodementia" | |
| |
| |
| |
| Miscellaneous Dementia Syndromes | |
| |
| |
| Normal Pressure Hydrocephalus | |
| |
| |
| Trauma and Dementia Pugilistica | |
| |
| |
| Neoplasia-Related Dementia | |
| |
| |
| Multiple Sclerosis | |
| |
| |
| Epilepsy | |
| |
| |
| Miscellaneous Unclassified Dementias | |
| |
| |
| |
| Pharmacotherapy of Alzheimer's Disease and Other Dementias | |
| |
| |
| Cholinergic Agents | |
| |
| |
| Antioxidants | |
| |
| |
| Other Cognitive Agents | |
| |
| |
| Herbal Remedies | |
| |
| |
| Summary of Cognitive Pharmacotherapy for Alzheimer's Disease | |
| |
| |
| Psychoactive Medications | |
| |
| |
| |
| Nonpharmacologic Management of Dementia | |
| |
| |
| ABCs of Dementia Management | |
| |
| |
| Diagnostic Interaction | |
| |
| |
| Family Instruction | |
| |
| |
| Caregiver Support | |
| |
| |
| Psychosocial Issues | |
| |
| |
| Advanced Dementia Care | |
| |
| |
| Special Issues | |
| |
| |
| |
| Conclusions and Directions | |
| |
| |
| Concepts and Attitudes About Dementia | |
| |
| |
| Demographic Projections | |
| |
| |
| Prevention and Early Detection | |
| |
| |
| Biological Markers | |
| |
| |
| Pharmacotherapy | |
| |
| |
| Future Strategies | |
| |
| |
| Index | |