| Contributing Authors | p. xiii |
| Foreword | p. xxiii |
| Preface | p. xxv |
| Basic Mechanisms of Epileptogenesis | |
| Cellular Aspects of Epileptogenesis | |
| Basic Cellular Neurophysiology | p. 3 |
| Neurotransmitters and Receptors | p. 25 |
| Mechanisms of Epileptogenesis and Experimental Models of Seizures | p. 33 |
| Neuronal Migration Disorders: Developmental and Neuroanatomic Aspects | |
| Brain Developmental Milestones and Pathologic Correlation | p. 45 |
| Cerebral Dysgenesis and Epilepsy | p. 65 |
| Cortical Anatomy: Normal and Abnormal Sulcal and Gyral Patterns | p. 79 |
| Hippocampal Sclerosis: Neuroanatomic and Neurophysiologic Aspects | |
| Normal Hippocampal and Temporal Anatomy | p. 93 |
| Hippocampal Sclerosis: Pathology, Electrophysiology, and Mechanisms of Epileptogenesis | p. 105 |
| Genetics and Epidemiology | |
| Genetic Aspects of Epilepsy | p. 115 |
| The Epidemiology of Epilepsy | p. 131 |
| Remission, Intractability, Mortality, and Comorbidity of Seizures | p. 139 |
| Basic Principles of Electroencephalography | |
| Neurophysiologic Basis of the Electroencephalogram | p. 149 |
| Polarity, Localization, and Field Determination in Electroencephalography | p. 165 |
| Clinical Use of the Electroencephalogram in the Diagnosis of Epilepsy | p. 193 |
| Computer-Assisted Data Collection and Analysis | p. 209 |
| Electroencephalographic Atlas of Epileptiform Abnormalities | p. 225 |
| Epileptic Seizures and Syndromes | |
| Epileptic Seizures | |
| Classification of Seizures | p. 287 |
| Proposal for Revised Clinical and Electrographic Classification of Epileptic Seizures: Commission on Classification and Terminology of the International League Against Epilepsy | p. 291 |
| Epileptic Auras | p. 299 |
| Complex Partial Seizures | p. 309 |
| Focal Motor Seizures and Epilepsia Partialis Continua | p. 329 |
| Supplementary Sensorimotor Area Seizures | p. 345 |
| Absence Seizures | p. 357 |
| Generalized Tonic-Clonic Seizures | p. 369 |
| Myoclonic Seizures | p. 395 |
| Tonic and Atonic Seizures | p. 405 |
| Infantile Spasms | p. 415 |
| Epileptic Syndromes | |
| Classification of the Epilepsies | p. 453 |
| Proposal for Revised Classification of Epilepsies and Epileptic Syndromes: Commission on Classification and Terminology of the International League Against Epilepsy | p. 457 |
| Symptomatic Focal Epilepsies | p. 467 |
| Idiopathic and Benign Partial Epilepsies | p. 475 |
| Childhood and Juvenile Absence Epilepsies | p. 485 |
| Juvenile Myoclonic Epilepsy | p. 491 |
| The Progressive Myoclonus Epilepsies | p. 509 |
| Symptomatic Generalized Epilepsy and Lennox-Gastaut Syndrome | p. 525 |
| Epilepsy with Reflex Seizures | p. 537 |
| Less Common Epilepsy Syndromes | p. 551 |
| Seizures in Special Clinical Settings | |
| Neonatal Seizures | p. 577 |
| Febrile Seizures | p. 601 |
| Posttraumatic Epilepsy | p. 609 |
| Brain Tumors and Epilepsy | p. 615 |
| Epilepsy in the Setting of Neurocutaneous Syndromes | p. 627 |
| Epilepsy in the Setting of Inherited Metabolic and Mitochondrial Disorders | p. 637 |
| Seizures Associated with Nonneurologic Medical Conditions | p. 657 |
| Catamenial Epilepsy and Issues of Fertility, Sexuality, and Reproduction | p. 671 |
| Status Epilepticus | p. 681 |
| Differential Diagnosis of Epilepsy | |
| Psychogenic Seizures | p. 699 |
| Other Nonepileptic Paroxysmal Disorders | p. 705 |
| Antiepileptic Medications | |
| General Principles of Antiepileptic Drug Therapy | |
| Antiepileptic Drug Development | p. 719 |
| Pharmacokinetics and Pharmacodynamics of Antiepileptic Drugs | p. 729 |
| Pharmacokinetics in Infancy, Childhood, and Adolescence | p. 741 |
| Initiating Drug Therapy | p. 759 |
| Long-Term Therapy with Antiepileptic Drugs | p. 769 |
| Treatment of Epilepsy During Pregnancy | p. 775 |
| Treatment of Epilepsy in the Elderly | p. 787 |
| Treatment of Epilepsy in the Setting of Renal and Liver Disease | p. 795 |
| Discontinuting Antiepileptic Drug Therapy | p. 811 |
| Specific Antiepileptic Medications and Other Therapies | |
| Carbamazepine and Oxcarbazepine | p. 821 |
| Valproate | p. 843 |
| Phenytoin and Fosphenytoin | p. 853 |
| Phenobarbital and Primidone | p. 869 |
| Ethosuximide | p. 881 |
| Benzodiazepines | p. 893 |
| Gabapentin | p. 915 |
| Lamotrigine | p. 933 |
| Topiramate | p. 939 |
| Tiagabine | p. 947 |
| Felbamate | p. 953 |
| Vigabatrin | p. 61 |
| Adrenocorticotropin and Steroids | p. 969 |
| Newer Antiepileptic Drugs | p. 977 |
| Less Commonly Used Antiepileptic Drugs | p. 985 |
| The Ketogenic Diet | p. 1001 |
| Vagus Nerve Stimulation | p. 1007 |
| Epilepsy Surgery | |
| Identification of Candidates and Presurgical Evaluation | |
| Recognition of Potential Surgical Candidates and Video Electroencephalography Evaluation | p. 1019 |
| MRI Techniques in the Evaluation for Epilepsy Surgery | p. 1031 |
| The Intracarotid Amobarbital Procedure | p. 1043 |
| Metabolic and Functional Neuroimaging | p. 1053 |
| Intracranial Electroencephalography and Localization Studies | p. 1067 |
| Epilepsy Surgery in Specifics Settings | |
| Selection of Candidates for Temporal Resection | p. 1077 |
| Selection of Candidates for Extratemporal Resection | p. 1095 |
| Resection for Epilepsy in the Setting of a Focal Lesion on MRI | p. 1115 |
| Resection for Epilepsy in the Setting of a Nonlocalizing MRI | p. 1135 |
| Hemispherectomy | p. 1147 |
| Epilepsy Surgery in Infants and Children | p. 1161 |
| Corpus Callosotomy and Multiple Subpial Transection | p. 1175 |
| New Techniques: Gamma Knife | p. 1185 |
| Deep Brain Stimulation for Epilepsy | p. 1193 |
| Outcome and Complications of Epilepsy Surgery | p. 1197 |
| Psychosocial Aspects of Epilepsy | |
| Cognitive Effects of Epilepsy and Antiepileptic Medications | p. 1215 |
| Psychiatric Aspects of Epilepsy | p. 1227 |
| Quality of Life with Epilepsy | p. 1243 |
| Legal Aspects of Epilepsy | p. 1251 |
| Indications for Antiepileptic Drugs Sanctioned by the United States Food and Drug Administration | p. 1257 |
| Subject Index | p. 1259 |
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