Concepts in Biochemistry

ISBN-10: 0534380069

ISBN-13: 9780534380069

Edition: 2nd 2002

Authors: Rodney F. Boyer

List price: $103.95
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This book reflects the modern tendency of biochemical studies and experimental design to be more heavily based on the nucleic acids and genetic approaches. Boyer enhances student's understanding of biological processes by initiating the study of biochemistry with nucleic acids (especially DNA) playing a more central role and treating other biomolecules as direct or indirect products. Boyer's lively presentation captures students' interest, gives them a current and practical sense of biochemistry, and presents applications that they can use in their careers and everyday lives. An accompanying interactive CD-ROM/Web site provides additional opportunities for study and enrichment.Boyer includes all the topical coverage usually provided in current biochemistry courses, but modifies the sense of focus and balance of coverage. The result is a text of exceptional relevance for students in allied-health fields, agricultural studies, and related programs.
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Book details

List price: $103.95
Edition: 2nd
Copyright year: 2002
Publisher: Wadsworth
Binding: Hardcover
Pages: 652
Language: English

Molecules and Lifep. 1
Biochemistry: Setting the Stagep. 3
The Roots of Modern Biochemistryp. 5
Living Matter Contains C, H, O, N, P, and Sp. 9
Biological Macromoleculesp. 11
Organelles, Cells, and Organismsp. 13
The Flow of Biological Information: Cell Communicationp. 29
Storage of Biological Information in DNAp. 31
Transfer of Biological Information to RNAp. 34
Protein Synthesisp. 36
Errors in DNA Processingp. 39
Information Flow Through Cell membranesp. 40
Diseases of Cellular Communication and Drug Designp. 43
Biomolecules in Waterp. 47
Water, the Biological Solventp. 49
Hydrogen Bonding and Solubilityp. 52
Cellular Reactions of Waterp. 55
Buffer Systemsp. 61
Amino Acids, Peptides, and Proteinsp. 69
The Amino Acids in Proteinsp. 70
Polypeptides and Proteinsp. 78
Protein Functionp. 79
Protein Size, Composition, and Propertiesp. 82
Four Levels of Protein Structurep. 84
Protein Primary Structurep. 84
Dynamic Function of Biomoleculesp. 95
Protein Architecture and Biological Functionp. 97
General Principles of Protein Designp. 98
Elements of Secondary Structurep. 102
Protein Tertiary Structurep. 107
Protein Quaternary Structurep. 110
Protein Structure and Biological Functionp. 111
Enzymes I: Reactions, Kinetics, and Inhibitionp. 125
Enzymes As Biological Catalystsp. 126
The Kinetic Properties of Enzymesp. 130
Substrate Binding and Enzyme Actionp. 136
Enzyme Inhibitionp. 141
Enzymes II: Coenzymes, Regulation, Abzymes, and Ribozymesp. 155
Enzyme: Coenzyme Partnersp. 156
Allosteric Enzymesp. 161
Cellular Regulation of Enzymesp. 167
Site-Directed Mutagenesis and Abzymesp. 170
Ribozymesp. 172
Carbohydrates: Structure and Biological Functionp. 179
Monosaccharidesp. 180
Carbohydrates in Cyclic Structuresp. 182
Reactions of Monosaccharidesp. 186
Polysaccharidesp. 192
Glycoproteinsp. 198
Lipids, Biological Membranes, and Cellular Transportp. 207
Fatty Acidsp. 209
Triacylglycerolsp. 211
Polar Lipidsp. 216
Steroids and Other Lipidsp. 219
Biological Membranesp. 225
Membrane Transportp. 229
Examples of Membrane Transportp. 232
Storage and Transfer of Biological Informationp. 241
DNA and RNA: Structure and Functionp. 243
RNA and DNA Chemical Structuresp. 244
DNA Structural Elementsp. 251
RNA Structural Elementsp. 258
Cleavage of DNA and RNA by Nucleasesp. 261
Nucleic Acid-Protein Complexesp. 264
DNA Replication and Transcription: Biosynthesis of DNA and RNAp. 271
Replication of DNAp. 272
Action of DNA Polymerasesp. 277
DNA Damage and Repairp. 283
Synthesis of RNAp. 287
Post-transcriptional Modification of RNAp. 293
Base Sequences in DNAp. 298
Translation of RNA: The Genetic Code and Protein Metabolismp. 305
The Process of Protein Synthesisp. 306
The Three Stages of Protein Synthesisp. 312
Post-Translational Processing of Proteinsp. 320
Regulation of Protein Synthesis and Gene Expressionp. 325
Recombinant DNA and Other Topics in Biotechnologyp. 337
Recombinant DNA Technologyp. 338
Preparing Recombinant DNAp. 342
DNA Amplification by the Polymerase Chain Reactionp. 349
Applications of Recombinant DNA Technologyp. 352
Metabolism and Energyp. 363
Basic Concepts of Cellular Metabolism and Bioenergeticsp. 365
Intermediary Metabolismp. 368
The Chemistry of Metabolismp. 372
Concepts of Bioenergeticsp. 379
Metabolism of Carbohydratesp. 393
The Energy Metabolism of Glucosep. 395
Entry of Other Carbohydrates into Glycolysisp. 400
Pyruvate Metabolismp. 403
Biosynthesis of Carbohydratesp. 406
Regulation of Carbohydrate Metabolismp. 413
Production of NADH and NADPH: The Citric Acid Cycle, the Glyoxylate Cycle, and the Phosphogluconate Pathwayp. 423
The Pyruvate Dehydrogenase Complexp. 425
The Citric Acid Cyclep. 433
The Citric Acid Cycle in Regulation and Biosynthesisp. 438
The Glyoxylate Cyclep. 441
The Phosphogluconate Pathwayp. 443
ATP Formation by Electron-Transport Chainsp. 449
Mitochondrial Electron Transportp. 450
Components of the Electron-Transport Chainp. 454
Oxidative Phosphorylationp. 459
Recycling of Cytoplasmic NADHp. 463
Photosynthetic Electron Transportp. 465
Synthesis of Carbohydrates by the Calvin Cyclep. 478
Metabolism of Fatty Acids and Lipidsp. 487
Metabolism of Dietary Triacylglycerolsp. 488
Catabolism of Fatty Acidsp. 493
Biosynthesis of Fatty Acidsp. 502
Cholesterolp. 507
Transport of Lipids in Bloodp. 514
Metabolism of Amino Acids and Other Nitrogenous Compoundsp. 523
The Nitrogen Cyclep. 524
Biosynthesis of Amino Acidsp. 528
Catabolism of Amino Acidsp. 532
Elimination of NH[superscript + subscript 4]p. 538
Amino Acids as Precursors of Other Biomoleculesp. 541
Integration, Coordination, and Specialization in Metabolismp. 557
Overall Strategies of Metabolismp. 558
Metabolic Specialization and Integrationp. 561
Metabolic Control by Hormonesp. 566
Metabolic Responses to Stressful Conditionsp. 568
Biochemical Factors in Obesityp. 571
Glossaryp. 577
Answers to Study Exercisesp. 589
Creditsp. 615
Indexp. 617
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