Monoclonal Antibodies Production, Engineering and Clinical Application

Name: Monoclonal Antibodies Production, Engineering and Clinical Application
Price: 9.89 USD
Availability: InStock
ISBN: 9780521425032

ISBN-10: 0521425034

ISBN-13: 9780521425032

Edition: 1994

Authors: Mary A. Ritter, Heather M. Ladyman

List price: $116.00

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Description:

Monoclonal antibodies have a very important and wide-ranging role in many areas of biomedical research and this volume is amongst the very first to combine technical and clinical aspects of the subject. Monoclonal antibodies provide highly specific reagents with which to identify, analyse, quantitate and manipulate molecules - both in solution and in solid phase, such as at a cell surface. The aim of this book is therefore to provide a unique combination of the production (by both cellular and molecular biology techniques), structure and functional characteristics of monoclonal antibodies, together with detailed discussions of the various analytic, diagnostic and therapeutic applications of…

Book details

List price: $116.00
Copyright year: 1994
Publisher: Cambridge University Press
Publication date: 1/26/1995
Binding: Paperback
Pages: 500
Size: 6.69" wide x 9.65" long x 0.98" tall
Weight: 1.738
Language: English




Introduction



Production of monoclonal antibodies



Antigen-antibody interactions: how affinity and kinetics affect assay design and selection procedures



The production and characterisation of synthetic peptide-derived antibodies



Human monoclonal antibodies



Bispecific monoclonal antibodies



The production of antibodies using phage display libraries



Genetic manipulation of monoclonal antibodies



Monoclonal antibodies in diagnostic immunoassays



Monoclonal antibodies in diagnostic pathology



In vivo targeting of monoclonal antibodies for immunoscintigraphy and therapy of human malignancies



Monoclonal antibodies in infectious disease: diagnosis



Monoclonal antibodies in the prophyllaxis and therapy of infectious disease



Monoclonal antibodies in transplantation: immunohistology



Monoclonal antibodies in transplantation: experimental studies on in vivo immunosuppression



Monoclonal antibodies in transplantation: prophyllaxis of graft-versus-host disease after bone marrow transplantation



Monoclonal antibodies in transplantation: use as therapeutic agents in clinical organ transplantation



Monoclonal antibodies and the skin



Monoclonal antibodies in endocrinology



Monoclonal antibodies in rheumatology



Technical appendix