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Monoclonal Antibodies Production, Engineering and Clinical Application

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ISBN-10: 0521425034

ISBN-13: 9780521425032

Edition: 1994

Authors: Mary A. Ritter, Heather M. Ladyman

List price: $126.00
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Description:

Monoclonal antibodies have a very important and wide-ranging role in many areas of biomedical research and this volume is amongst the very first to combine technical and clinical aspects of the subject. Monoclonal antibodies provide highly specific reagents with which to identify, analyse, quantitate and manipulate molecules - both in solution and in solid phase, such as at a cell surface. The aim of this book is therefore to provide a unique combination of the production (by both cellular and molecular biology techniques), structure and functional characteristics of monoclonal antibodies, together with detailed discussions of the various analytic, diagnostic and therapeutic applications of…    
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Book details

List price: $126.00
Copyright year: 1994
Publisher: Cambridge University Press
Publication date: 1/26/1995
Binding: Paperback
Pages: 500
Size: 7.25" wide x 10.00" long x 1.25" tall
Weight: 2.134
Language: English

Introduction
Production of monoclonal antibodies
Antigen-antibody interactions: how affinity and kinetics affect assay design and selection procedures
The production and characterisation of synthetic peptide-derived antibodies
Human monoclonal antibodies
Bispecific monoclonal antibodies
The production of antibodies using phage display libraries
Genetic manipulation of monoclonal antibodies
Monoclonal antibodies in diagnostic immunoassays
Monoclonal antibodies in diagnostic pathology
In vivo targeting of monoclonal antibodies for immunoscintigraphy and therapy of human malignancies
Monoclonal antibodies in infectious disease: diagnosis
Monoclonal antibodies in the prophyllaxis and therapy of infectious disease
Monoclonal antibodies in transplantation: immunohistology
Monoclonal antibodies in transplantation: experimental studies on in vivo immunosuppression
Monoclonal antibodies in transplantation: prophyllaxis of graft-versus-host disease after bone marrow transplantation
Monoclonal antibodies in transplantation: use as therapeutic agents in clinical organ transplantation
Monoclonal antibodies and the skin
Monoclonal antibodies in endocrinology
Monoclonal antibodies in rheumatology
Technical appendix