| |
| |
| List of Contributors | |
| |
| |
| Preface | |
| |
| |
| Acknowledgments | |
| |
| |
| Introduction | |
| |
| |
| What is Pharmacoepidemiology | |
| |
| |
| Study Design Available for Pharmacoepidemiology Studies | |
| |
| |
| Sample Size Considerations for Pharmacoepidemiology Studies | |
| |
| |
| Basic Principles of Clinical Pharmacology Relevant to Pharmacoepidemiology Studies | |
| |
| |
| When Should One Perform Pharmacoepidemiology Studies | |
| |
| |
| Perspectives On Pharmacoepidemiology | |
| |
| |
| A View from Academia | |
| |
| |
| A View from Industry | |
| |
| |
| A View from Regulatory Agencies | |
| |
| |
| Sources Of Data For Pharmacoepidemiology Studies | |
| |
| |
| Ad Hoc Data Sources Available for Pharmacoepidemiology Studies | |
| |
| |
| Spontaneous Reporting in the United States | |
| |
| |
| Global Drug Surveillance: The WHO Programme for International Drug Monitoring | |
| |
| |
| Case-Control Surveillance | |
| |
| |
| Prescription-Event Monitoring | |
| |
| |
| Automated Data Systems Available for Pharmacoepidemiology Studies | |
| |
| |
| Overview of Automated Databases in Pharmacoepidemiology | |
| |
| |
| Group-Health Cooperative | |
| |
| |
| Kaiser Permanente Medical Care Program | |
| |
| |
| The HMO Research Network | |
| |
| |
| UnitedHealth Group | |
| |
| |
| Medicaid Databases | |
| |
| |
| Health Services Databases in Saskatchewan | |
| |
| |
| Automated Pharmacy Record Linkage in the Netherlands | |
| |
| |
| The Tayside Medicines Monitoring Unit (MEMO) | |
| |
| |
| The UK General Practice Research Database | |
| |
| |
| Other Approaches to Pharmacoepidemiology Studies | |
| |
| |
| Other Approaches to Pharmacoepidemiology Studies | |
| |
| |
| How Should One Perform Pharmacoepidemiology Studies? Choosing Among the Available Alternatives | |
| |
| |
| Selected Special Applications Of Pharmacoepidemiology | |
| |
| |
| National Medicinal Drug Policies: Their Relationship to Pharmacoepidemiology | |
| |
| |
| Premarketing Applications of Pharmacoepidemiology | |
| |
| |
| Studies of Drug Utilization | |
| |
| |
| Evaluating and Improving Physician Prescribing | |
| |
| |
| Drug Utilization Review | |
| |
| |
| Special Methodological Issues in Pharmacoepidemiology Studies of Vaccine Safety | |
| |
| |
| Pharmacoepidemiologic Studies of Devices | |
| |
| |
| Studies of Drug-Induced B | |