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Epilepsy in Children and Adolescents

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ISBN-10: 0470741236

ISBN-13: 9780470741238

Edition: 2nd 2012

Authors: Gregory Cascino, Dave F. Clarke, Amy L. McGregor, Freedom Perkins, Yu-Tze Ng

List price: $106.00
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Description:

This book provides the contemporary, caring guidance you need to diagnose and manage seizures in a young patient. Beginning with an overview of the classification of seizure syndromes, the authors take a practical approach to a common but complex clinical challenge. Aimed at both professionals and trainees in neurology, this book will also be a useful guide for all primary health professionals caring for pediatric patients with this condition. It is intended as a foundation for further study into pediatric epilepsy and to serve as a quick, up–to–date reference for the recognition, diagnosis, basic understanding, evaluation and management of this condition in children and adolescents.
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Book details

List price: $106.00
Edition: 2nd
Copyright year: 2012
Publisher: John Wiley & Sons, Limited
Publication date: 11/23/2012
Binding: Hardcover
Pages: 396
Size: 6.75" wide x 9.50" long x 0.80" tall
Weight: 1.628
Language: English

List of contributors
Preface
Epidemiology and classification of childhood epilepsies
Epidemiology and common comorbidities of epilepsy in childhood
Epidemiology
Incidence and prevalence
Gender and age
Classification
Febrile seizures
Etiology
Psychiatric comorbidity
Psychological and psychosocial stress related to chronic disease
Psychiatric symptoms related to medication side effects
Psychiatric comorbidity related to epilepsy pathophysiology
Attention-deficit/hyperactivity disorder (ADHD)
Anxiety
Depression
Intellectual and developmental disabilities (IDD)
Conclusion
References
Classification and definition of seizures and epilepsy syndromes in childhood
Introduction
Purpose and goals of definitions and classification
Systems of classification and definitions
Seizures
Generalized seizures
Focal seizures
Syndromes
Specific age-related epilepsy syndromes
Future directions
Acknowledgements
References
Initiating and withdrawing medical management
Initiating medical management
The chances of seizure recurrence after the first unprovoked seizure
Seizure recurrence
The possible adverse effects of seizure recurrence
The risks of initiating antiepileptic drug therapy
The benefits of initiating antiepileptic drug therapy
How to initiate treatment with antiepileptic drugs
Special circumstances
Summary: initiating medical management
Withdrawing medical management
The long-term prognosis of childhood-onset epilepsy
When to consider discontinuing antiepileptic drug therapy
Risk factors for seizure recurrence after discontinuation
The risks of discontinuing antiepileptic drug therapy
The benefits of discontinuing antiepileptic drug therapy
How to discontinue antiepileptic drugs
Special circumstances
Summary: withdrawing medical management
Disclaimer
References
Common genetic and neurocutaneous disorders in childhood epilepsy
Idiopathic epilepsies
Symptomatic epilepsies
Epilepsy in common chromosomal abnormalities
Epilepsy in metabolic and mitochondrial disorders
Epilepsy in malformations of cortical development
Neurocutaneous disorders
Summary
References
Diagnostic evaluation of childhood epilepsies
Evaluating the child with seizures
Emergent diagnosis and management
Subsequent evaluation
Additional neurodiagnostic evaluation
References
The use of EEG in the diagnosis of childhood epilepsy
Technical aspects of the EEG
Methods used to increase EEG yield
When should an EEG be ordered?
EEG findings in epilepsy and epilepsy syndromes
Neonatal EEGs
The EEG in focal epilepsy
The EEG of generalized epilepsy
Specific disease-related epilepsy syndromes
Conclusion
References
Imaging of pediatric epilepsy
Introduction
Imaging considerations
Congenital malformations
Neoplasms
Acquired/idiopathic abnormalities
References
Non-epileptic paroxysmal events of childhood
Introduction
Breath-holding spells
Parasomnias
Benign paroxysmal positional vertigo of childhood
Syncope
Paroxymal non-epileptic events (PNEs) with a psychiatric or behavioral basis
Hyperekplexia
Alternating hemiplegia of childhood
Movement disorders
Sandifer syndrome
Conclusion
References
Principles of treatment
Pharmacology of antiepileptic drugs
Pharmacokinetics
Pharmacogenomics
References
Therapeutic efficacy of antiepileptic drugs
Efficacy-based treatment guidelines
Antiepileptic drug selection based on specific pediatric epilepsy syndromes
Influence of comorbidities in children with epilepsy
Conclusions
References
Adverse effects of antiepileptic drugs
Introduction
Specific drugs
At-risk profiles and monitoring
References
Vagus nerve stimulation therapy and epilepsy surgery
Vagus nerve stimulation
Epilepsy surgery
Conclusions
References
Dietary therapies to treat epilepsy
History
Efficacy
Mechanism of action
Selection of candidates for the diet
Initiation and maintenance
Complications
The ketogenic diet in the twenty-first century
References
Resources
Websites
Generalized seizures and generalized epilepsy syndromes
Idiopathic generalized epilepsies
Clinical features
Natural history
Genetics
Treatment
Classification
Myoclonic epilepsy in infancy
Childhood absence epilepsy (CAE)
Juvenile absence epilepsy (JAE)
Juvenile myoclonic epilepsy (JME)
Epilepsy with generalized tonic-clonic seizures alone (IGE-GTCs)
Epilepsy with myoclonic absence
Epilepsy with myoclonic-atonic seizures/Doose syndrome
Febrile seizures plus (FS+)
Eyelid myoclonia with absences (EMA)/Jeavons syndrome
Summary
References
Cryptogenic and symptomatic generalized epilepsies: epilepsies with encephalopathy
Neonatal-onset epilepsies with encephalopathy
Infantile-onset epilepsies with encephalopathy
Epilepsies with encephalopathy with onset later in infancy
Epilepsies with encephalopathy with onset after infancy
Continuous spike wave of sleep (CSWS) and Landau-Kleffner syndrome (LKS)
References
Partial-onset seizures and localization-related epilepsy syndromes
Idiopathic partial epilepsies
Benign infantile seizures
Benign childhood epilepsy with centrotemporal spikes
Childhood occipital epilepsy (Panayiotopoulos type)
Late-onset childhood occipital epilepsy (Gastaut type)
References
Cryptogenic and symptomatic partial epilepsies
Etiology
Seizure phenomena
Temporal lobe epilepsy
Extratemporal epilepsy
Occipital lobe epilepsy
Parietal lobe epilepsy
Hypothalamic hamartoma
Other localizing and lateralizing signs
References
Epilepsies relative to age, etiology, or duration
Neonatal seizures
Significance of neonatal seizures
Pathophysiology of neonatal seizures
Classification and clinical features of neonatal seizures
Electrographic seizures
Monitoring and recording
Etiology of neonatal seizures
Metabolic causes for neonatal seizures
Inborn errors of metabolism
Treatment
Chronic postnatal epilepsy and the need for long-term treatment
Potential adverse effects of antiepileptic drugs on the immature CNS
Conclusion
References
Febrile seizures
Introduction
Definition
Incidence and prevalence
Pathophysiology
Prognosis
Initial evaluation and management
Long-term management
Management in practice
Genetics
Parent counseling
Conclusion
References
Status epilepticus in childhood
Definition
Epidemiology
Pathophysiology
Etiology
Diagnosis and investigations
EEG patterns in status epilepticus
Treatment
Prognosis
References
Index