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Heterocycles in Life and Society An Introduction to Heterocyclic Chemistry, Biochemistry and Applications

ISBN-10: 0470714107

ISBN-13: 9780470714102

Edition: 2nd 2011

Authors: Alexander F. Pozharskii, Alan R. Katritzky, A. T. Soldatenkov

List price: $42.95
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Description:

Heterocycles in Life and Society is an introduction to the chemistry of heterocyclic compounds, focusing on their origin and occurrence in nature, biochemical significance and wide range of applications. Written in a readable and accessible style, the book takes a multidisciplinary approach to this extremely important area of organic chemistry. Topics covered include an introduction to the structure and properties of heterocycles; the key role of heterocycles in important life processes such as the transfer of hereditary information, how enzymes function, the storage and transport of bioenergy, and photosynthesis; applications of heterocycles in medicine, agriculture and industry; heterocycles in supramolecular chemistry; the origin of heterocycles on primordial Earth; and how heterocycles can help us solve 21st century challenges. For this second edition, Heterocycles in Life and Society has been completely revised and expanded, drawing on a decade of innovation in heterocyclic chemistry. The new edition includes discussions of the role of heterocycles in nanochemistry, green chemistry, combinatorial chemistry, molecular devices and sensors, and supramolecular chemistry. Impressive achievements include the creation of various molecular devices, the recording and storage of information, the preparation of new organic conductors, and new effective drugs and pesticides with heterocyclic structures. Much new light has been thrown on various life processes, while the chemistry of heterocycles has expanded to include new types of heterocyclic structures and reactions, and the use of heterocyclic molecules as ionic liquids and proton sponges. Heterocycles in Life and Society is an essential guide to this important field for students and researchers in chemistry, biochemistry, and drug discovery, and scientists at all levels wishing to expand their scientific horizon.
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Book details

List price: $42.95
Edition: 2nd
Copyright year: 2011
Publisher: John Wiley & Sons, Limited
Publication date: 4/13/2011
Binding: Paperback
Pages: 396
Size: 6.50" wide x 9.50" long x 0.75" tall
Weight: 0.990
Language: English

Preface to Second English Edition
Preface to First English Edition
Molecular Rings Studded With Jewels
From Homocycle to Heterocycle
Building Heterocycles From Benzene
Some More Kinds of Heterocycles
Problems
Suggested Reading
Why Nature Prefers Heterocycles
Reactions for all Tastes
Heterocycles as Acids and Bases
Heterocycles and Metals
'There are Subtle Ties of Power…'
The van der Waals-London Interactions
Hydrogen Bonding
Electrostatic Interactions
Molecular Complexes
Hydrophobic Forces
Tautomerism: Heterocycles and Their 'Masks'
Problems
Suggested Reading
Heterocycles and Hereditary Information
Nucleic Acids
The Double Helix
How One DNA Doubles Itself
Protein Synthesis, Genetic Code and the Genome
What are Mutations?
Mysterious Telomeres
Gene Expression
Problems
Suggested Reading
Enzymes, Coenzymes and Vitamins
Molecular Robots
Coenzymes and Enzymes as 'Joint Molecular Ventures'
Oxidative-Reductive Coenzymes
Coenzymes as Carriers of Molecular Species
Vitamins, the 'Molecules of Health'
Ribozymes: Vestiges of an Ancient World
Problems
Suggested Reading
Heterocycles and Bioenergetics
ATP as the Universal Currency of Energy
Breathing
Glycolysis
The Krebs Cycle, or the 'Molecular Merry-Go-Round'
The Respiratory Chain
Problems
Suggested Reading
Heterocycles and Photosynthesis
Chlorophyll: Sunlight-Receiving Antenna and Energy Carrier
What Daylight can Achieve
Photosynthesis Without Light
Problems
Suggested Reading
Heterocycles and Health
Medicines From a Natural Storehouse
Heterocycles Versus Infectious Microbes
In Search of 'Magic Bullets'
Sulfanilamides and Heterocycles
Antibiotics
Antibiotics From the Ocean's Depths
Heterocyclic Antifungal Agents
Heterocycles Against Parasitic Diseases
Heterocycles and Viral Infections
Heterocycles and the Diseases of Our Century
Heterocycles to Cure Stress, Brain Disorders and Pain
Heterocycles and Cardiovascular Diseases
Heterocycles and Malignant Tumors
Heterocyclic Molecules in Combat with Ulcers and Sexual Dysfunctions
Problems
Suggested Reading
Heterocycles in Agriculture
A Century of Chemical Warfare Against Weeds
Regulators of Plant Growth
The Struggle Against Voracious Insects
Resisting the Kingdoms of Mustiness and Rot
Heterocycles in Animal Husbandry
Combinatorial Chemistry and Functional Genomics in the Synthesis of Biologically Active Heterocyclic Compounds
Problems
Suggested Reading
Heterocycles in Industry and Technology
Heterocycles and Natural Colors
Dyes
From Imperial Cloaks to Jeans
'Cyanine' Means Azure
Phthalocyanines: Sometimes Better than Porphyrins
The Anchoring of Dyes
Fluorescent Agents
Why They Shine
Safety and Aesthetics
How to Convert White into Snow White
Markers and Tracers
Imaging and Diagnostic Agents
Lasers Containing Heterocyclic Luminophores
Color Change Compounds
Fire Retardancy
Photographic Materials and Recorders of Information
Heterocycles as Food Additives
Heterocycles as Cosmetics and Perfumery Ingredients
Other Applications
Problems
Suggested Reading
Heterocycles and Supramolecular Chemistry
Molecular Recognition and Host-Guest Interactions
Cation Receptors
Anion-, Betaine- and Ionic Associated Receptors
Receptors for Neutral Molecules
Molecular Carcerands
Molecular Containers for the Proton
Self-Assembling Molecular Systems
Problems
Suggested Reading
Heterocycles and Twenty-First Century Challenges
Energy Problem
Biofuels
Hydrogen as a Fuel
Direct Use of Solar Energy
Conducting Materials
Ecology and Green Chemistry
Biotechnology and Related Problems
Enzyme Technologies
DNA Technologies
New Trends in Health Care
Heterocycles as Molecular Sensors
From Molecular Devices to Molecular Computer
Problems
Suggested Reading
The Origin of Heterocycles
The Origin of the Universe and the Appearance of Chemical Elements
Interstellar Molecules
Organic Compounds in Comets and Meteorites
Do Heterocycles Exist on the Moon and Mars?
The Atmosphere of Earth and Other Planets
Heterocycles and the Origin of the Biosphere
Simple Precursors of Heterocycles
Heterocyclic Amino Acids
Pyrroles and Porphyrins
Furanose Sugars
Nicotinamide
Purines and Pyrimidines
Nucleosides and Nucleotides
Polynucleotides and the Birth of 'Animated' Organic Molecules
Problems
Suggested Reading
Conclusion
Answers and References to Selected Problems
Index