Organic Synthesis The Disconnection Approach

ISBN-10: 0470712368

ISBN-13: 9780470712368

Edition: 2nd 2009

Authors: Stuart Warren, Paul Wyatt, Stuart G. Warren

List price: $50.00
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Organic Synthesis: The Disconnection Approach is the long-awaited second edition of a classic textbook; the first to provide a structured course in retrosynthesis- now an important technique used by generations of organic chemists. Now fully revised and updated with a modern look, 25 years of advances in organic synthesis are reflected with the addition of new examples and synthetic pathways. Additional material has been added to take the student to the level required by the bestselling sequel, "Organic Synthesis: Strategy and Control" and the later chapters have extensive new material based on courses that the authors give to chemists in the pharmaceutical industry.
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Book details

List price: $50.00
Edition: 2nd
Copyright year: 2009
Publisher: John Wiley & Sons, Incorporated
Publication date: 12/31/2008
Binding: Paperback
Pages: 344
Size: 7.25" wide x 9.50" long x 0.75" tall
Weight: 1.320
Language: English

General References
The Disconnection Approach
Basic Principles: Synthons and Reagents Synthesis of Aromatic Compounds
Strategy I: The Order of Events
One-Group C-X Disconnections
Strategy II: Chemoselectivity
Two-Group C-X Disconnections
Strategy III: Reversal of Polarity, Cyclisations, Summary of Strategy
Amine Synthesis
Strategy IV: Protecting Groups
One Group C-C Disconnections I: Alcohols
General Strategy A: Choosing a Disconnection
Strategy V: Stereoselectivity A
One Group C-C Disconnections II: Carbonyl Compounds
Strategy VI: Regioselectivity
Alkene Synthesis
Strategy VII: Use of Acetylenes (Alkynes)
Two-Group C-C Disconnections I: Diels-Alder Reactions
Strategy VIII: Introduction to Carbonyl Condensations
Two-Group C-C Disconnections II: 1,3-Difunctionalised Compounds
Strategy IX: Control in Carbonyl Condensations
Two-Group C-C Disconnections III: 1,5-Difunctionalised Compounds Conjugate (Michael) Addition and Robinson Annelation
Strategy X: Aliphatic Nitro Compounds in Synthesis
Two-Group Disconnections IV: 1,2-Difunctionalised Compounds
Strategy XI: Radical Reactions in Synthesis
Two-Group Disconnections V: 1,4-Difunctionalised Compounds
Strategy XII: Reconnection
Two-Group C-C Disconnections VI: 1,6-diCarbonyl Compounds
General Strategy B: Strategy of Carbonyl Disconnections
Strategy XIII: Introduction to Ring Synthesis: Saturated Heterocycles
Three-Membered Rings
Strategy XIV: Rearrangements in Synthesis
Four-Membered Rings: Photochemistry in Synthesis
Strategy XV: The Use of Ketenes in Synthesis
Five-Membered Rings
Strategy XVI: Pericyclic Reactions in Synthesis: Special Methods for Five-Membered Rings
Six-Membered Rings
General Strategy C: Strategy of Ring Synthesis
Strategy XVII: Stereoselectivity B
Aromatic Heterocycles
General Strategy D: Advanced Strategy
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