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Preface | |
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Recommended reading | |
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Acknowledgements | |
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List of abbreviations | |
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Introduction | |
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Overview of the cardiovascular system | |
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Anatomy and histology | |
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Gross anatomy and histology of the heart | |
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Vascular anatomy | |
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Vascular histology and smooth muscle cell ultrastructure | |
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Blood and body fluids | |
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Constituents of blood | |
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Erythropoiesis, haemoglobin and anaemia | |
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Haemostasis | |
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Thrombosis and anticoagulants | |
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Blood groups and transfusions | |
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Cellular physiology | |
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Membrane potential, ion channels and pumps | |
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Electrophysiology of cardiac muscle and origin of the heart beat | |
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Cardiac muscle excitation-contraction coupling | |
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Electrical conduction system in the heart | |
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The electrocardiogram | |
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Vascular smooth muscle excitation-contraction coupling | |
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Form and function | |
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Cardiac cycle | |
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Control of cardiac output | |
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Haemodynamics | |
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Blood pressure and flow in the arteries and arterioles | |
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The microcirculation and lymphatic system, and diapedesis | |
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Fluid filtration in the microcirculation | |
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The venous system | |
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Local control of blood flow | |
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Regulation of the vasculature by the endothelium | |
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The coronary, cutaneous and cerebral circulations | |
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The pulmonary, skeletal muscle and fetal circulations | |
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Integration and regulation | |
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Cardiovascular reflexes | |
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Autonomic control of the cardiovascular system | |
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The control of blood volume | |
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Cardiovascular effects of exercise | |
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Shock and haemorrhage | |
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History, examination and investigations | |
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History and examination of the cardiovascular system | |
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Cardiovascular investigations | |
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Pathology and therapeutics | |
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Risk factors for cardiovascular disease | |
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�-Blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers and Ca<sup>2+</sup> channel blockers | |
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Hyperlipidaemias | |
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Atherosclerosis | |
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Treatment of hypertension | |
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Mechanisms of primary hypertension | |
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Stable and variant angina | |
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Pharmacological management of stable and variant angina | |
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Acute coronary syndromes: Unstable angina and non-ST segment elevation myocardial infarction | |
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Revascularization | |
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Pathophysiology of acute myocardial infarction | |
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Acute coronary syndromes: ST segment elevation myocardial infarction | |
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Heart failure | |
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Treatment of chronic heart failure | |
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Mechanisms of arrhythmia | |
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Supraventricular tachyarrhythmias | |
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Ventricular tachyarrhythmias and non-pharmacological treatment of arrhythmias | |
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Pharmacological treatment of arrhythmias | |
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Pulmonary hypertension | |
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Diseases of the aortic valve | |
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Diseases of the mitral valve | |
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Genetic and congenital heart disease | |
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Self-assessment | |
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Case studies and questions | |
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Case studies answers | |
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Index | |