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Preface | |
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A GC/MS Primer | |
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Introduction | |
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Why Use GC/MS? | |
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Interpretation of Fragmentation Data Versus Spectral Library Searching | |
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The Gas Chromatograph/Mass Spectrometer | |
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Systems and Costs | |
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Competitive Analytical Systems | |
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Sample Preparation and Introduction | |
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Direct Sample Injection into the Mass Spectrometer | |
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Sample Purification | |
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Manual GC Injection | |
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Automated GC/MS Injection | |
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The Gas Chromatography | |
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The GC Oven and Temperature Control | |
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Selecting GC Columns | |
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Separation Parameters and Resolution | |
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GC Control Variables | |
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Derivatives | |
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The Mass Spectrometer | |
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Vacuum Pumps | |
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Interfaces and Sources | |
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Quadrupole Operation | |
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The Ion Detector | |
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Getting Started in GC/MS | |
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Mode Selection | |
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Setting Up | |
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Mass Spectrometer Tuning and Calibration | |
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Sample Injection and Chromatographic Separation | |
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Data Collection Processing | |
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A GC/MS Optimization | |
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Chromatographic Methods Development | |
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Isothermal Operation | |
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Linear Temperature Gradients | |
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Assisted Re-Equilibration | |
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Hinge Point Gradient Modification | |
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Pressure Gradient Development | |
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Column Replacement | |
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Mass Spectrometer Setup and Operation | |
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Mass Spectrometer Calibration with Calibration Gases | |
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Mass Axis Tuning | |
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System Tuning for Environmental Analysis | |
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Acquiring Information | |
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Data Displays and Library Searches | |
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Data Processing and Network Interfacing | |
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Peak Identification and Integration | |
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Multi-Instrument Control | |
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Networking Connection | |
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Replacement Control and Processing Systems | |
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File Conversion and Data File Exchange | |
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Data Re-Entry and Transcription Errors | |
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System Maintenance and Troubleshooting | |
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Gas Chromatograph Maintenance | |
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Mass Spectrometer Maintenance | |
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System Electrical Grounding | |
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Specific Applications of GC/MS | |
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GC/MS in The Environmental Laboratory | |
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Volatile Organic Analysis: EPA Method 624 | |
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SemiVolatile Organic Analysis: EPA Method 625 | |
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EPA and State Reporting Requirements | |
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GC/MS in Forensics, Toxicology, and Space Science | |
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Forensic Analysis | |
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Clinical Drug Analysis | |
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Arson and Security Analysis | |
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Astrochemistry | |
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An Introduction to Structural Interpretation | |
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History of the Sample | |
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Elemental Composition | |
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Search for Logical Fragmentation Intervals | |
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Ion Trap GC/MS Systems | |
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Ion Trap Components | |
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Ion Trap Operation | |
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The Linear Ion Trap Analyzer | |
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Ion Traps in the Environmental Laboratory | |
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Chemical Ionization in the Ion Trap | |
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Ion Trap GC/MS/MS | |
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Other GC/MS Systems | |
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Sequential Mass Spectrometry (Triple-Quadrupole or Tandem GC/MS) | |
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Magnetic Sector Systems | |
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Laser Time-of-Flight (GC/TOF-MS) GC/MS Systems | |
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Fourier Transform (GC/FT-MS) GC/MS Systems | |
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An Introduction to LC/MS | |
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Liquid Interfacing into the Mass Spectrometer | |
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Electrospray and Nano-Spray LC/MS | |
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Ion Spray LC/MS | |
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LC/MS/MS | |
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LC/MS Versus GC/MS | |
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Innovation in GC/MS | |
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Microfludics in GC/MS | |
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Resistance Column Heating | |
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Portable Gas Supply | |
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Portable GC/MS Systems | |
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New Column Technology | |
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GC/MS Frequently Asked Questions | |
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GC FAQs | |
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Column FAQs | |
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MS FAQs | |
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GC/MS FAQs | |
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GC/MS Troubleshooting Quick Reference | |
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GC Injector Problems | |
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GC Column Problems | |
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MS Vacuum and Power Problems | |
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MS Source and Calibration Problems | |
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MS Sensitivity and Detector Problems | |
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Sources of GC/MS Background Contamination | |
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A Glossary of GC/MS Terms | |
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GC/MS Selected Reading List | |
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Journals | |
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Books | |
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Index | |