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Preface | |
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Abbreviations used in this book | |
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Greek letters used in this book | |
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Colour coding for molecules | |
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Viruses and their importance | |
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Viruses are ubiquitous on Earth | |
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Reasons for studying viruses | |
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The nature of viruses | |
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The remainder of the book | |
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Methods used in virology | |
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Introduction to methods used in virology | |
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Cultivation of viruses | |
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Isolation of viruses | |
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Centrifugation | |
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Structural investigations of cells and virions | |
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Electrophoretic techniques | |
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Detection of viruses and virus components | |
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Infectivity assays | |
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Virus genetics | |
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Virus structure | |
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Introduction to virus structure | |
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Virus genomes | |
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Virus proteins | |
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Capsids | |
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Virion membranes | |
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Occlusion bodies | |
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Other virion components | |
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Virus transmission | |
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Introduction to virus transmission | |
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Transmission of plant viruses | |
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Transmission of vertebrate viruses | |
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Transmission of invertebrate viruses | |
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Permissive cells | |
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Attachment and entry of viruses into cells | |
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Overview of virus replication | |
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Animal viruses | |
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Bacteriophages | |
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Transcription, translation and transport | |
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Introduction to transcription, translation and transport | |
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Transcription of virus genomes | |
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Transcription in eukaryotes | |
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Translation in eukaryotes | |
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Transport in eukaryotic cells | |
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Transcription and translation in bacteria | |
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Virus genome replication | |
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Overview of virus genome replication | |
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Locations of virus genome replication in eukaryotic cells | |
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Initiation of genome replication | |
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Polymerases | |
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DNA replication | |
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Double-stranded RNA replication | |
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Single-stranded RNA replication | |
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Reverse transcription | |
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Assembly and exit of virions from cells | |
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Introduction to assembly and exit of virions from cells | |
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Nucleocapsid assembly | |
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Formation of virion membranes | |
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Virion exit from the infected cell | |
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Outcomes of infection for the host | |
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Introduction to outcomes of infection for the host | |
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Factors affecting outcomes of infection | |
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Non-productive infections | |
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Productive infections | |
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Classification and nomenclature of viruses | |
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History of virus classification and nomenclature | |
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Modern virus classification and nomenclature | |
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Baltimore classification of viruses | |
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Herpesviruses (and other dsDNA viruses) | |
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Introduction to herpesviruses | |
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The human herpesviruses | |
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The herpesvirus virion | |
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HSV-1 genome organization | |
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HSV-1 replication | |
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Latent herpesvirus infection | |
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Other dsDNA viruses | |
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Parvoviruses (and other ssDNA viruses) | |
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Introduction to parvoviruses | |
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Examples of parvoviruses | |
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Parvovirus virion | |
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Parvovirus replication | |
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Other ssDNA viruses | |
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Reoviruses (and other dsRNA viruses) | |
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Introduction to reoviruses | |
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Rotavirus virion | |
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Rotavirus replication | |
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Other dsRNA viruses | |
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Picornaviruses (and other plus-strand RNA viruses) | |
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Introduction to picornaviruses | |
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Some important picornaviruses | |
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The picornavirus virion | |
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Picornavirus replication | |
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Picornavirus recombination | |
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Picornavirus experimental systems | |
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Other plus-strand RNA viruses | |
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Rhabdoviruses (and other minus-strand RNA viruses) | |
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Introduction to rhabdoviruses | |
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Some important rhabdoviruses | |
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The | |