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| List of Figures | |
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| List of Tables | |
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| List of Case Studies | |
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| Acknowledgements | |
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| Abbreviations | |
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| Introduction | |
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| Basic Immunology | |
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| Key Definitions | |
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| Introduction | |
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| Overview of Defence Mechanisms | |
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| Cells and Organs of the Immune System | |
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| Innate Immune Responses I | |
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| Innate Immune Responses II - The Complement System | |
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| Innate Immune Responses III - Other Soluble Factors | |
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| Inflammation | |
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| What the Immune System Recognises | |
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| Human Leucocyte Antigen (HLA) Molecules | |
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| Antigen Presentation | |
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| How Does the Immune System See Antigen? | |
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| Lymphocyte Maturation | |
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| Immunoglobulin Structure | |
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| B Cell Activation | |
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| Immunoglobulin Function | |
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| T Cell Receptor and Immune Repertoire | |
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| Helper T Cell Activation | |
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| Cytotoxic T Cells | |
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| The Mucosal Immune System | |
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| Initiation of the Immune Response | |
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| Maintenance of the Immune Response | |
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| Control of the Immune Response | |
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| Ontogeny of the Immune Response | |
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| Immune Responses to Infection | |
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| How Organisms Evade the Immune System | |
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| Consequences of an Immune Response | |
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| Host Defence Against Tumours | |
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| Autoimmunity | |
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| Hypersensitivity | |
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| Atopy and Allergic Inflammation | |
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| Self Assessment | |
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| Clinical Immunology | |
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| Clinical Manifestations of Atopy | |
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| Asthma | |
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| Urticaria and Angioedema | |
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| Food Allergy | |
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| Anaphylaxis | |
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| Other Types of Hypersensitivity Reactions | |
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| Immunodeficiency | |
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| Defects in Antibody-mediated Immunity | |
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| Defects in T Cell-mediated Immunity | |
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| Neutrophil Disorders | |
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| Complement Deficiency | |
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| Defective Splenic Function | |
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| Human Immunodeficiency Virus | |
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| Autoimmunity | |
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| Autoimmune Endocrinopathies | |
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| Immune-mediated Haematological Conditions | |
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| Autoimmune Liver Diseases | |
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| Immune-mediated Gastrointestinal Disorders | |
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| Immune-mediated Neurological Disease | |
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| Immune-mediated Skin Disease | |
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| Immune-mediated Renal Disease | |
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| Rheumatoid Disease and Spondylarthropathies | |
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| Connective Tissue Diseases | |
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| Vasculitis | |
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| Hypersensitivity Induced by Pathogens | |
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| Transplantation | |
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| Haemopoietic Stem Cell Transplantation | |
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| Solid Organ Transplantation | |
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| Lymphoid Malignancies | |
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| Leukaemia and Lymphoma | |
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| Plasma Cell Diseases | |
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| Self Assessment | |
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| Immunotechniques and Diagnostic Tests Used in Clinical Immunology | |
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| Laboratory Tests in Clinical Immunology | |
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| Antibodies are Essential Tools in the Clinical Immunology Laboratory | |
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| Detection of Antibodies and Antigen | |
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| Autoantibody Profiles in Connective Tissue Diseases and Rheumatoid Disease | |
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| Autoantibodies Associated with Vasculitic Syndromes and Renal Diseases | |
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| Autoantibodies Associated with Liver and Gastrointestinal Diseases | |
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| Autoantibodies Associated with Endocrine Diseases and Pernicious Anaemia | |
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| Other Organ-specific Autoimmunity | |
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| Measurement of the Acute Phase Response | |
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| Complement | |
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| Immunodeficiency | |
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| Abnormal Immunoglobulins | |
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| Angioedema: C1-Inhibitor Disorders | |
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| Allergy and Hypersensitivity | |
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| Transplantation | |
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| Immunophenotyping Leukaemias and Lymphomas | |
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| Direct Immunofluorescence | |
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| Self Assessment | |
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| Treatment of Immunological Disorders | |
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| Principles of Immunosuppression | |
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| Corticosteroids | |
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| Immunosuppression (I) | |
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| Immunosuppression (II) | |
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| Therapeutic Antibody Production | |
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| Targeted Cell Depletion | |
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| Other Antibody Therapies | |
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| Immunoglobulin Replacement Therapy | |
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| High Dose Immunoglobulin Therapy | |
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| Cytokines | |
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| Vaccination and Passive Immunisation | |
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| Plasmapheresis and Plasma Exchange | |
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| Management of Acute Allergic Reactions | |
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| Self Assessment | |
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| Clinical Immunology - Future Prospects | |
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| Glossary | |
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| Index | |