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The Hodgkin-Huxley Equations | |
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The Resting Potential | |
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The Nernst Equation | |
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The Goldman-Hodgkin-Katz Equation | |
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Equivalent Circuits: The Electrical Analogue | |
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The Membrane Time Constant | |
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The Cable Equation | |
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The Squid Action Potential | |
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Voltage-Gated Channels | |
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Hodgkin-Huxley Model | |
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The Action Potential Revisited | |
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Bibliography | |
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Exercises | |
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Dendrites | |
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Multiple Compartments | |
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The Cable Equation | |
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The Infinite Cable | |
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Finite and Semi-infinite Cables | |
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Branching and Equivalent Cylinders | |
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An Isolated Junction | |
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Dendrites with Active Processes | |
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Concluding Remarks | |
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Bibliography | |
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Exercises | |
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Dynamics | |
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Introduction to Dynamical Systems | |
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The Morris-Lecar Model | |
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The Phase Plane | |
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Stability of Fixed Points | |
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Excitable Systems | |
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Oscillations | |
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Bifurcation Analysis | |
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The Hopf Bifurcation | |
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Saddle-Node on a Limit Cycle | |
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Saddle-Homoclinic Bifurcation | |
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Class I and Class II | |
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Bifurcation Analysis of the Hodgkin-Huxley Equations | |
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Reduction of the Hodgkin-Huxley Model to a Two-Variable Model | |
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FitzHugh-Nagumo Equations | |
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Bibliography | |
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Exercises | |
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The Variety of Channels | |
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Overview | |
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Sodium Channels | |
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Calcium Channels | |
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Voltage-Gated Potassium Channels | |
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A-Current | |
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M-Current | |
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The Inward Rectifier | |
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Sag | |
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Currents and Ionic Concentrations | |
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Calcium-Dependent Channels | |
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Calcium Dependent Potassium: The Afterhyperpolarization | |
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Calcium-Activated Nonspecific Cation Current | |
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Bibliography | |
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Exercises | |
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Projects | |
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Bursting Oscillations | |
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Introduction to Bursting | |
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Square-Wave Bursters | |
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Elliptic Bursting | |
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Parabolic Bursting | |
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Classification of Bursters | |
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Chaotic Dynamics | |
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Chaos in Square-Wave Bursting Models | |
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Symbolic Dynamics | |
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Bistability and the Blue-Sky Catastrophe | |
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Bibliography | |
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Exercises | |
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Propagating Action Potentials | |
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Traveling Waves and Homoclinic Orbits | |
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Scalar Bistable Equations | |
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Numerical Shooting | |
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Singular Construction of Waves | |
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Wave Trains | |
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Dispersion Relations | |
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Dispersion Kinematics | |
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Morris-Lecar Revisited and Shilnikov Dynamics | |
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Class II Dynamics | |
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Class I Dynamics | |
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Stability of the Wave | |
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Linearization | |
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The Evans Function | |
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Myelinated Axons and Discrete Diffusion | |
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Bibliography | |
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Exercises | |
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Synaptic Channels | |
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Synaptic Dynamics | |
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Gluiamate | |
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�-Aminobutyric Acid | |
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Gap or Electrical Junctions | |
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Short-Term Plasticity | |
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Other Models | |
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Long-Term Plasticity | |
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Bibliography | |
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Exercises | |
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Neural Oscillators: Weak Coupling | |
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Neural Oscillators, Phase, and Isochrons | |
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Phase Resetting and Adjoints | |
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The Adjoint | |
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Examples of Adjoints | |
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Bifurcations and Adjoints | |
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Spike-Time Response Curves | |
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Who Cares About Adjoints? | |
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Relationship of the Adjoint and the Response to Inputs | |
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Forced Oscillators | |
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Coupled Oscillators | |
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Other Map Models | |
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Weak Coupling | |
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Geometric Idea | |
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Applications of Weak Coupling | |
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Synaptic Coupling near Bifurcations | |
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Small Central Pattern Generators | |
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Linear Arrays of Cells | |
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Two-Dimensional Arrays | |
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All-to-All Coupling | |
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Pulse-Coupled Networks: Solitary Waves | |
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Integrate-and-Fire Model | |
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Stability | |
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Bibliography | |
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Exercises | |
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Projects | |
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Neuronal Networks: Fast/Slow Analysis | |
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Introduction | |
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Mathematical Models for Neuronal Networks | |
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Individual Cells | |
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Synaptic Connections | |
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Network Architecture | |
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Examples of Firing Patterns | |
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Singular Construction of the Action Potential | |
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Synchrony with Excitatory Synapses | |
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Postinhibitory Rebound | |
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Two Mutually Coupled Cells | |
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Clustering | |
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Dynamic Clustering | |
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Antiphase Oscillations with Excitatory Synapses | |
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Existence of Antiphase Oscillations | |
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Stability of Antiphase Oscillations | |
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Almost-Synchronous Solutions | |
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Almost Synchrony with Inhibitory Synapses | |
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Almost Synchrony with Excitatory Synapses | |
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Synchrony with Inhibitory Synapses | |
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Slow Inhibitory Synapses | |
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Fast/Slow Decomposition | |
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Antiphase Solution | |
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Suppressed Solutions | |
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Propagating Waves | |
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Bibliography | |
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Exercises | |
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Noise | |
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Stochastic Differential Equations | |
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The Wiener Process | |
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Stochastic Integrals | |
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Change of Variables: It�'s Formula | |
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Fokker-Planck Equation: General Considerations | |
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Scalar with Constant Noise | |
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First Passage Times | |
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Firing Rates of Scalar Neuron Models | |
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The Fokker-Planck Equation | |
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First Passage Times | |
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Interspike Intervals | |
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Colored Noise | |
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Nonconstant Inputs and Filtering Properties | |
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Weak Noise and Moment Expansions | |
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Poisson Processes | |
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Basic Statistics | |
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Channel Simulations | |
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Stochastic Spike Models: Beyond Poisson | |
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Bibliography | |
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Exercises | |
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Projects | |
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Firing Rate Models | |
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A Number of Derivations | |
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Heuristic Derivation | |
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Derivation from Averaging | |
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Populations of Neurons | |
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Population Density Methods | |
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The Wilson-Cowan Equations | |
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Scalar Recurrent Model | |
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Two-Population Networks | |
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Excitatory-Inhibitory Pairs | |
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Generalizations of Firing Rate Models | |
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Beyond Mean Field | |
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Some Methods for Delay Equations | |
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Exercises | |
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Projects | |
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Spatially Distributed Networks | |
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Introduction | |
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Unstructured Networks | |
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McCulloch-Pitts | |
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Hopfield's Model | |
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Designing Memories | |
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Waves | |
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Wavefronts | |
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Pulses | |
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Bumps | |
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The Wilson-Cowan Equations | |
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Stability | |
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More General Stability | |
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More General Firing Rates | |
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Applications of Bumps | |
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Spatial Patterns: Hallucinations | |
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Exercises | |
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References | |
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Index | |