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Molecular Biology of RNA

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ISBN-10: 0199288372

ISBN-13: 9780199288373

Edition: 2010

Authors: David Elliott, Michael Ladomery

List price: $42.99
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For many years, RNA was thought to have something of a supplementary role in genome function - an intermediate in the flow of biological information from gene to protein. In recent years, however, the centrality of RNA as a key player in gene expression has become clear; it is far from being merely a staging post between gene and protein. Instead, new insights into RNA structure and function have revolutionized our view of molecular biology, and the role of RNA in the evolution oflife itself.Molecular Biology of RNA is the first student text to provide a broad survey of RNA structure and function. It leads the reader through the life cycle of an RNA, placing particular emphasis on…    
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Book details

List price: $42.99
Copyright year: 2010
Publisher: Oxford University Press
Publication date: 1/19/2016
Binding: Paperback
Pages: 468
Size: 10.40" wide x 7.50" long x 0.70" tall
Weight: 2.134
Language: English

David Elliott is a Reader in Genetics at the Institute of Human Genetics, Newcastle University, UK Michael Ladomery is Principal Investigator in the RNA Biology group, School of Life Sciences, University of the West of England, UK.

Introduction: what is post-transcriptional gene regulation?
The versatility of RNA structure
RNA catalysis
The RNA binding proteins
Capping, cleavage and nuclear polyadenylation
Pre-mRNA splicing- Part 1, nuts and bolts
Pre-mRNA splicing- Part 2, the central role of introns and splicing in eukaryotic gene expression
Regulated RNA processing- How pre-mRNAs are decoded by the splicing machinery
Regulated RNA processing- Alternative splicing
pre-mRNA processing in development and disease
Nucleocytoplasmic traffic of mRNAs
Nucleocytoplasmic traffic of noncoding RNAs
mRNA localisation
mRNA translation
mRNA stability and decay
rRNA and tRNA processing
RNA Editing
RNA interference and microRNAs
Long non-coding RNAs
RNA techniques