| |
| |
Contributors | |
| |
| |
| |
Fundamentals of Human Genome Epidemiology Revisited | |
| |
| |
| |
Human Genome Epidemiology: The Road Map Revisited | |
| |
| |
| |
| |
Principles of Analysis of Germline Genetics | |
| |
| |
| |
| |
The Public Health Genomics Enterprise | |
| |
| |
| |
| |
Navigating the Evolving Knowledge of Human Genetic Variation in Health and Disease | |
| |
| |
| |
| |
Methods and Approaches for Data Collection, Analysis, and Integration | |
| |
| |
| |
The Global Emergence of Epidemiological Biobanks: Opportunities and Challenges | |
| |
| |
| |
| |
Case-Control and Cohort Studies in the Age of Genome-wide Associations | |
| |
| |
| |
| |
The Emergence of Networks in Human Genome Epidemiology: Challenges and Opportunities | |
| |
| |
| |
| |
Design and Analysis Issues in Genome-wide Association Studies | |
| |
| |
| |
| |
The Challenge of Assessing Complex Gene-Environment and Gene-Gene Interactions | |
| |
| |
| |
| |
STrengthening the REporting of Genetic Association Studies (STREGA)-an Extension of the STROBE Statement | |
| |
| |
| |
| |
Integration of the Evidence on Gene-Disease Associations: Methods of HuGE Reviews | |
| |
| |
| |
| |
Genome-wide Association Studies, Field Synopses, and the Development of the Knowledge Base on Genetic Variation and Human Diseases | |
| |
| |
| |
| |
Case Studies: Cumulative Assessment of the Role of Human Genome Variation in Specific Diseases | |
| |
| |
| |
Colorectal Cancer | |
| |
| |
| |
| |
Childhood Leukemias | |
| |
| |
| |
| |
Bladder Cancer | |
| |
| |
| |
| |
Type 2 Diabetes | |
| |
| |
| |
| |
Osteoporosis | |
| |
| |
| |
| |
Preterm Birth | |
| |
| |
| |
| |
Coronary Heart Disease | |
| |
| |
| |
| |
Schizophrenia | |
| |
| |
| |
| |
Applications of Epidemiologic Methods for Using Genetic Information in Medicine and Public Health | |
| |
| |
| |
Mendelian Randomization: The Contribution of Genetic Epidemiology to Elucidating Environmentally Modifiable Causes of Disease | |
| |
| |
| |
| |
Evaluation of Predictive Genetic Tests for Common Diseases: Bridging Epidemiological Clinical and Public Health Measures | |
| |
| |
| |
| |
The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: Methods of the EGAPP Working Group | |
| |
| |
| |
| |
Rapid, Evidence-based Reviews of Genetic Tests | |
| |
| |
| |
| |
Role of Social and Behavioral Research in Assessing the Utility of Genetic Information | |
| |
| |
| |
| |
Assessing the Evidence for Clinical Utility in Newborn Screening | |
| |
| |
| |
| |
The Role of Epidemiology in Assessing the Potential Clinical Impact of Pharmacogenomics | |
| |
| |
| |
| |
The Human Epigenome and Cancer | |
| |
| |
| |
| |
The Use of Family History in Public Health Practice: The Epidemiologic View | |
| |
| |
| |
| |
Case Studies: Assessing the Use of Genetic Information in Practice for Specific Diseases | |
| |
| |
| |
Cytochrome P450 Testing in the Treatment of Depression | |
| |
| |
| |
| |
A Rapid-ACCE Review of CYP2C9 and VKORC1 Allele Testing to Inform Warfarin Dosing in Adults at Elevated Risk for Thrombotic Events to Avoid Serious Bleeding | |
| |
| |
| |
| |
Hereditary Hemochromatosis: Population Screening for Gene Mutations | |
| |
| |
| |
Index | |