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| Preface | |
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| Introduction | |
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| The Case of Allergic Disease: From Everyday Observation to Microstructural Explanation | |
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| Experimentation and Research Science | |
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| Observable Mysteries | |
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| Physical Microstructure | |
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| Mechanism and Testing | |
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| Mast Cell Release | |
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| Immunoglobulin E | |
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| Intervention and Manipulation | |
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| Released Inflammatory Mediator Blockade | |
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| Mast Cell Release Blockade | |
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| Immunoglobulin E Blockade | |
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| Unification and Explanation | |
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| IgE--anthelminthic | |
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| Allergy Genes | |
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| Determination and Explanation | |
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| The Positivist Model of Scientific Theories | |
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| Theories as Formal Languages | |
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| A Dummy Scientific Theory to Illustrate the Positivist Model | |
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| Trouble in Positivist Paradise | |
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| The Point of the Observational/Theoretical Distinction | |
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| Ease of Application | |
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| Instrumentation | |
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| Putnamian Cynicism | |
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| Encapsulated Information Processing | |
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| Sensory Surface Distance | |
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| Correspondence-Rules | |
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| Dispositional Properties | |
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| Holism | |
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| The Underdetermination of Theory | |
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| The Quine-Duhem Thesis | |
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| Popperian Falsificationism | |
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| Is Underdetermination a Myth? | |
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| Pragmatism and Realism | |
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| Reductionism, Antireductionism, and Supervenience | |
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| Nagel's Model of Reduction | |
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| Kemeny & Oppenheim's Model of Reduction | |
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| The Unity of Science Program | |
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| The Putnam/Fodor Multiple Realization Argument Against the Unity of Science | |
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| Supervenience to the Rescue? | |
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| Kim's Model of Supervenience | |
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| Modest Physicalism | |
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| The Structure of Scientific Explanation | |
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| The Deductive-Nomological (D-N) Model of Scientific Explanation | |
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| Laws of nature32<l>6.1.2</l> | |
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| The Aleatory Model of Scientific Explanation | |
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| The Unification Model of Scientific Explanation | |
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| Natural Kinds, Homeostatic Property Clusters, and the Structural Basis of Reality | |
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| The Revenge of Historicism | |
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| Anti-Incrementalism | |
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| Paradigms and the Practice of Normal Science | |
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| Puzzle-Solving and the Cautiousness of Normal Science | |
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| Anomalies | |
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| Revolutionary Science | |
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| Antirealism, Relativism, and Their Shadows | |
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| The Case of Modern Immunology | |
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| The Social Constructivist Challenge | |
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| The Strong Programme | |
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| Roll Over Socrates: Philosophy as the Bad Guy | |
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| The Case Method with a Vengeance | |
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| The View from Deep in the Swamp of History | |
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| The Inequality of Theoretical Alternatives | |
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| The Politics of Epistemology | |
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| The Genderization of Scientific Knowledge | |
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| Postmodernist Feminism: Sandra Harding | |
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| Feminist Social Activism: Helen Longino | |
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| Feminist Empiricism: Lynn Hankinson Nelson | |
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| The Actual Way Things Really Are | |
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| What Can or Cannot Happen in the Limit of Inquiry | |
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| The Cosmic Coincidence Argument for Scientific Realism | |
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| The Covergence Argument | |
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| The Manipulability Argument | |
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| The Case for Scientific Antirealism | |
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| Antirealism: Success is Self-Defeating for Realism | |
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| Antirealism: Success Needs No Explanation at All | |
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| Antirealism: Success isn't What You Th | |