| |
| |
Foreword | |
| |
| |
| |
Contributors | |
| |
| |
| |
Psychiatric Epidemiology, Then and Now | |
| |
| |
| |
The Burden of Mental Illness | |
| |
| |
| |
The Arc of Epidemiology | |
| |
| |
| |
Searching for the Causes of Mental Disorders | |
| |
| |
| |
Risk Factors as Causes of Mental Disorders | |
| |
| |
| |
What Is a Cause? | |
| |
| |
| |
Detecting Causes | |
| |
| |
| |
Study Designs | |
| |
| |
| |
Relationships among Causes | |
| |
| |
| |
Measures of Association | |
| |
| |
| |
Cohort Designs in Psychiatric Epidemiology | |
| |
| |
| |
Prototypical Cohort Study | |
| |
| |
| |
Diversity of Cohort Studies | |
| |
| |
| |
Causal Inference: A Thought Experiment | |
| |
| |
| |
Confounding: What It Is and What Can Be Done | |
| |
| |
| |
Unequal Attrition under Different Types of Follow-Up | |
| |
| |
| |
Differential Misclassification | |
| |
| |
| |
Case-Control Designs in Psychiatric Epidemiology | |
| |
| |
| |
Logic of the Case-Control Design | |
| |
| |
| |
Applications of the Case-Control Study | |
| |
| |
| |
Choosing Controls | |
| |
| |
| |
Comparability and the Case-Control Study | |
| |
| |
| |
Case-Control Designs in Biologic Psychiatry | |
| |
| |
| |
Biologic Studies in Psychiatry | |
| |
| |
| |
Choosing Cases in Biologic Psychiatry | |
| |
| |
| |
Choosing Controls in Biologic Psychiatry | |
| |
| |
| |
Analyzing the Data | |
| |
| |
| |
Gauging the Precision of Measures of Association | |
| |
| |
| |
Using Significance Tests in Establishing Associations | |
| |
| |
| |
Planning Studies: Estimating Power and Sample Size | |
| |
| |
| |
Adjustment for Covariates | |
| |
| |
| |
Event Time Analysis | |
| |
| |
| |
Assessing Heterogeneity of Effects | |
| |
| |
| |
The Search for Genetic Causes of Mental Disorders | |
| |
| |
| |
Integrating Epidemiology with Genetics | |
| |
| |
| |
Genetic Association Studies | |
| |
| |
| |
Modern Family History Studies | |
| |
| |
| |
Twin Studies of Heritability | |
| |
| |
| |
Genetic Linkage Studies | |
| |
| |
| |
Designs for the Genomic Era | |
| |
| |
| |
Complex Causal Relationships | |
| |
| |
| |
Eco-Epidemiology | |
| |
| |
| |
Causal Explanation within a Risk Factor Framework | |
| |
| |
| |
Causal Explanation Outside the Black Box | |
| |
| |
| |
Dependent and Dynamic Processes | |
| |
| |
| |
Our Approach to Epidemiologic Concepts and Methods | |
| |
| |
| |
Application of Survival Analysis to Prenatal Determinants of Schizophrenia Example (PDSE) Data | |
| |
| |
Glossary | |
| |
| |
Index | |