Bioinformatics Computing

ISBN-10: 0131008250

ISBN-13: 9780131008250

Edition: 2003

Authors: Bryan Bergeron

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Description:

Bioinformatics Computing is a practical guide to computing in the growing field of Bioinformatics (the study of how information is represented and transmitted in biological systems, starting at the molecular level). This book brings life scientists at every level - from students to research directors - up to speed in computational techniques that apply directly to their work. The life science community needs a practical guide that illustrates the computer science advances that have been made in the past several decades in areas of computer visualization, large database designs, machine learning and other forms of advanced pattern matching, statistical methods, and distributed computing techniques. In addition to exploring general information technology issues, each chapter identifies technologies and approaches on the near horizon that will have a significant impact on bioinformatics, and introduces some of the global, societal issues that will likely define bioinformatics developments in the future.
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Book details

List price: $54.99
Copyright year: 2003
Publisher: Prentice Hall PTR
Publication date: 11/19/2002
Binding: Paperback
Pages: 439
Size: 7.00" wide x 9.50" long x 1.25" tall
Weight: 1.936
Language: English

Preface
Acknowledgments
The Central Dogma
The Killer Application
Parallel Universes
Watson's Definition
Top-Down Versus Bottom-Up
Information Flow
From Data to Knowledge
Convergence
Control
Archiving
Numerical Processing
Communications
Endnote
Databases
Definitions
Data Management
Pharmacogenomics and Aggression
Complexity
Data Life Cycle
Data Creation and Acquisition
Use
Data Modification
Archiving
Repurposing
Disposal
Managing the Life Cycle
Database Technology
Database Architecture
Database Management Systems
Interfaces
Implementation
Infrastructure
Endnote
Networks
Geographical Scope
Communications Models
Transmissions Technology
Protocols
Bandwidth
Topology
Hardware
Media
Network Electronics
Contents
Security
Antiviral Utilities
Authentication
Firewalls
Encryption
Process
Ownership
Implementation
Management
On the Horizon
Endnote
Search Engines
The Search Process
The Search
Results
Search Engine Technology
Intelligent Agents
Portals
User Interface Tools
Utilities
Searching and Information Theory
Computational Methods
Search Algorithms
Approximate Searches
Search Engines and Knowledge Management
On the Horizon
Endnote
Data Visualization
Sequence Visualization
Sequence Maps
Structure Visualization
Visualization Tools
Rendering Tools
User Interface
User Interface Components
Alternative Metaphors
Display Architecture
Animation Versus Simulation
General-Purpose Technologies
On the Horizon
Endnote
Statistics
Statistical Concepts
Progress
Microarrays
Imperfect Data
Basics
Randomness
Variability Is Cumulative
Approximation
Interface Noise
Assumptions
Sampling and Distributions
Hypothesis Testing
Quantifying Randomness
Data Analysis
Tool Selection
Statistics of Alignment
Clustering and Classification
On the Horizon
Endnote
Data Mining
Methods
Selection and Sampling
Preprocessing and Cleaning
Transformation and Reduction
Data-Mining Methods
Evaluation
Visualization
Designing New Queries
Technology Overview
Infrastructure
Pattern Recognition and Discovery
Machine Learning
Inductive Logic Programming
Genetic Algorithms
Neural Networks
Statistical Methods
Decision Trees
Hidden Markov Models
Text Mining
Natural Language Processing
Text Summarization
Tools
On the Horizon
Endnote
Pattern Matching
Fundamentals
Pairwise Sequence Alignment
Local Versus Global Alignment
Multiple Sequence Alignment
Computational Methods
Dot Matrix Analysis
Substitution Matrices
Dynamic Programming
Word Methods
Bayesian Methods
Multiple Sequence Alignment
Dynamic Programming
Progressive Strategies
Iterative Strategies
Other Strategies
Tools
Nucleotide Pattern Matching
Polypeptide Pattern Matching
Utilities
Sequence Databases
On the Horizon
Endnote
Modeling and Simulation
Drug Discovery
Fundamentals
Components
Process
Perspectives
Numeric Considerations
Algorithms
Hardware
Issues
Protein Structure
Ab Initio Methods
Heuristic Methods
Systems Biology
Tools
On the Horizon
Endnote
Collaboration
Collaboration and Communications
Asynchronous Communications
Synchronous Communications
Asynchronous Collaboration
Synchronous Collaboration
Standards
Niche Solutions
Tool and Data Accessibility
Data Uniformity
Interoperability
Open Source
Issues
Platform Dependence
Security
Intellectual Property
Economics
On the Horizon
Endnote
Bibliography
Index
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