Foundations of Comparative Genomics

Name: Foundations of Comparative Genomics
Price: 37.66 USD
Availability: InStock
ISBN: 9780120887941

ISBN-10: 0120887940

ISBN-13: 9780120887941

Edition: 2007

Authors: Arcady R. Mushegian

List price: $103.00

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Description:

This book provides a coherent and broadly accessible overview of how computational tools are used today to analyze genes and completely sequenced genomes. The field is presented from an historical perspective, beginning with its foundations in studies of microbial genomes, through to present day comparative genomics. The chapters highlight critical experimental and theoretical breakthroughs, presents their underlying scientific principles, and discusses their impact on modern research. The author covers the state-of-the-art, including systems biology and whole-genome phylogenetic reconstructions. *Presents a coherent view on the history and achievements of genome biology *Discusses the…

Book details

List price: $103.00
Copyright year: 2007
Publisher: Elsevier Science & Technology
Publication date: 5/24/2007
Binding: Hardcover
Pages: 280
Size: 7.24" wide x 10.24" long x 0.34" tall
Weight: 1.738



Preface



The Beginning of Computational Genomics



Finding Sequence Similarities



Homology: Can We Get It Right?



Getting Ready for the Era of Comparative Genomics: The Importance of Viruses



The First Fact of Comparative Genomics: Protein Sequences are Remarkably Resilient in Evolution



The Second Fact of Comparative Genomics: Functional Convergence at the Molecular Level



Prediction of Function and Reconstruction of Metabolism from Genomic Data: Homology-Based Approaches



Prediction of Function and Reconstruction of Metabolism: Post-Homology Approaches



Structural Genomics: What Does It Tell Us about Life?



How Many Protein Families are There?



Phylogenetic Inference and the Era of Complete Genomes



Two Stories about Evolution



Minimal and Ancestral Genomes



Comparative Genomics and Systems Biology


References


Index