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Hepatic Toxicology. Introduction to the liver and its responses to toxicants | |
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Structure and function of hepatic parenchymal cells | |
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Hepatic nonparenchymal cells: endothelial cells | |
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Cells of the liver: biliary epithelium | |
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Xenobiotic metabolism by the liver | |
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Evaluation of hepatotoxicity: physiological and biochemical measures of hepatic function | |
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Pathological response to toxic injury | |
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Xenobiotic-induced inflammation and injury in the liver | |
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Carcinogenic responses to toxic liver injury in rodents | |
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Antioxidant defense mechanisms | |
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Proteases and transcription factors: cutting edge determinants of the proliferative or apoptotic response in hepatic tissue | |
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Hepatic defenses against toxicity: regeneration | |
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In vitro methods | |
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Carbon tetrachloride | |
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Volatile halogenated hydrocarbons | |
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Hexachlorobenzene: effects on porphyrin metabolism | |
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Hepatotoxicity of the fluorinated anesthetic agent | |
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Role of Kupffer cells | |
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Cocaine hepatotoxicity | |
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Acetaminophen | |
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Effects of chlorpromazine on the liver | |
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Nitrofurantoin | |
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Isoniazid | |
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Pesticides | |
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Hepatotoxicity of copper | |
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Aflatoxin toxicology | |
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Pyrrolizidine alkaloids | |
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Bacterial endotoxin | |
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agr;-Naphthylisothiocyanate | |
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Allyl alcohol | |
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Bromobenzene hepatotoxicity: a paradigm of reactive electrophilic metabolites binding covalently to tissue macromolecules. Is there light at the end of the tunnel? | |
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D-galactosamine | |
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Thioacetamide | |
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The hepatotoxicity of Vitamin A | |
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Gastrointestinal Toxicology. Gastrointestinal system: introduction | |
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Anatomy esophagus stomach small intestine colon) | |
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Gastrointestinal system: overview of physiology | |
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The gastrointestinal tract immune system | |
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The metabolic barrier of the gastrointestinal tract | |
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Pathophysiological mechanisms of gastrointestinal toxicity | |
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Interaction of toxicants with gastrointestinal tract microbial flora | |
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Toxicants and gastrointestinal tract cellular proliferation and cancer | |
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Sources of gastrointestinal tract toxins | |
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Absorption | |
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Clinical toxicity of common drugs and chemicals: esophagus | |
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Clinical toxicity of common drugs and chemicals in humans: stomach | |
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Small bowel toxicology | |
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Clinical toxicity of common drugs and chemicals: colon | |
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In vitro and in vivo models of gastrointestinal toxicology | |
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Clinical toxicology in animals | |
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