| Using the Road Map Series for Successful Review | p. vii |
| Acknowledgments | p. ix |
| General Principles of Pharmacology | p. 1 |
| Definitions | p. 1 |
| Pharmacokinetic Principles | p. 1 |
| Pharmacodynamic Principles | p. 6 |
| Drug Development and Regulation | p. 10 |
| Clinical Problems | p. 11 |
| Answers | p. 12 |
| Autonomic Nervous System Pharmacology | p. 14 |
| Autonomic Anatomy | p. 14 |
| Transmitter Biochemistry | p. 14 |
| Physiology of Autonomic Action | p. 17 |
| Cholinomimetic Drugs | p. 20 |
| Cholinolytic Drugs and Pralidoxime | p. 22 |
| Sympathomimetics | p. 25 |
| Adrenoceptor Blockers | p. 27 |
| Clinical Problems | p. 29 |
| Answers | p. 30 |
| Drug Therapy for Cardiovascular Diseases | p. 31 |
| Hypertension | p. 31 |
| Angina Pectoris | p. 36 |
| Heart Failure | p. 38 |
| Cardiac Arrhythmias | p. 41 |
| Diuretics and Other Drugs Acting on the Kidney | p. 43 |
| Clinical Problems | p. 47 |
| Answers | p. 48 |
| Drugs for Allergy, Inflammation, and Blood and Immune Disorders | p. 49 |
| Histamine and Antihistaminics | p. 49 |
| Serotonin and Related Drugs | p. 49 |
| Eicosanoids | p. 52 |
| Nonsteroidal Anti-inflammatory Drugs and Drugs Used in Fever and Minor Pain and Headache | p. 53 |
| Drugs Used in Gout | p. 54 |
| Antilipid Drugs | p. 55 |
| Anticoagulants, Antiplatelet Drugs, and Fibrinolytics | p. 56 |
| Drugs Used in Anemias and Other Disorders of Blood Formation | p. 57 |
| Drugs Used in Asthma | p. 59 |
| Clinical Problems | p. 61 |
| Answers | p. 62 |
| Central Nervous System Drugs | p. 64 |
| Introduction to the Central Nervous System (CNS) Drugs | p. 64 |
| Sedative-Hypnotics | p. 64 |
| Antiepileptic Drugs (AEDs) | p. 69 |
| General Anesthetics | p. 71 |
| Local Anesthetics | p. 72 |
| Skeletal Muscle Relaxants | p. 73 |
| Drugs for Parkinsonism and Other Movement Disorders | p. 75 |
| Drugs for Psychoses and Bipolar Disorder | p. 77 |
| Antidepressants | p. 79 |
| Opioid Analgesics | p. 81 |
| Drugs of Abuse | p. 84 |
| Clinical Problems | p. 85 |
| Answers | p. 87 |
| Hormones and Other Endocrine Agents | p. 89 |
| Hypothalamic and Pituitary Drugs | p. 89 |
| Thyroid Drugs | p. 90 |
| Adrenal Steroids and Antagonists | p. 91 |
| Gonadal Drugs, Antagonists, and Inhibitors | p. 93 |
| Pancreatic Drugs | p. 94 |
| Drugs That Affect Bone Mineral Metabolism | p. 98 |
| Clinical Problems | p. 98 |
| Answers | p. 100 |
| Antimicrobial Agents: Antibiotics | p. 102 |
| Inhibitors of Cell Wall Synthesis: Penicillins | p. 102 |
| Inhibitors of Cell Wall Synthesis: Cephalosporins, Carbapenems, and Vancomycin | p. 104 |
| Inhibitors of Protein Synthesis: Macrolides, Clindamycin, Tetracyclines, and Chloramphenicol | p. 106 |
| Inhibitors of Protein Synthesis: Aminoglycosides, Streptogramins, and Linezolid | p. 108 |
| Inhibitors of Folic Acid Synthesis: Sulfonamides and Trimethoprim | p. 110 |
| Inhibitors of Nucleic Acid Synthesis: Fluoroquinolones | p. 112 |
| Antimycobacterial Drugs | p. 112 |
| Miscellaneous Antimicrobials | p. 114 |
| Clinical Problems | p. 115 |
| Answers | p. 117 |
| Antifungal, Antiviral, and Antiparasitic Drugs | p. 119 |
| Antifungal Drugs | p. 119 |
| Antiviral Drugs | p. 121 |
| Antiparasitic Drugs | p. 124 |
| Clinical Problems | p. 125 |
| Answers | p. 130 |
| Anticancer Drugs and Immunopharmacology | p. 132 |
| Cancer Chemotherapy | p. 132 |
| Immunopharmacology | p. 136 |
| Clinical Problems | p. 139 |
| Answers | p. 142 |
| Toxicology | p. 144 |
| Introduction | p. 144 |
| Environmental Chemicals | p. 144 |
| Agricultural Chemicals | p. 145 |
| Heavy Metals | p. 146 |
| Management of Poisoning | p. 146 |
| Clinical Problems | p. 149 |
| Answers | p. 151 |
| Special Topics | p. 153 |
| Gastrointestinal Pharmacology | p. 153 |
| Vaccines and Other Immunization Materials | p. 155 |
| Botanicals and Nutritional Supplements | p. 156 |
| Drug Interactions | p. 159 |
| Clinical Problems | p. 159 |
| Answers | p. 163 |
| Appendix | p. 165 |
| Index | p. 173 |
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