Goodman and Gilman's the Pharmacological Basis of Therapeutics

ISBN-10: 0071354697

ISBN-13: 9780071354691

Edition: 10th 2002

List price: $139.00
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The leading pharmacology reference since 1941 Throughout its 60 year history, Goodman & Gilman"s careful balance of basic science and clinical application has guided practitioners to a clear understanding of the drugs most useful in preventing, diagnosing and treating disease. It details how and why drugs affect different body systems, the chemical properties of drugs, dosage information, drug interactions and toxic effects. Well organised, extensively indexed, rigorously peer reviewed and referenced to the most up-to-date literature in the field, Goodman & Gilman"s is the definitive resource on therapeutics. It provides coverage of the general principles of pharmacology, including pharmacokinetics and pharmacodynamics, the principles of therapeutics, and the principles of toxicology and gene based therapy.
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Book details

List price: $139.00
Edition: 10th
Copyright year: 2002
Publisher: McGraw-Hill Professional Publishing
Publication date: 8/13/2001
Binding: Hardcover
Pages: 1825
Size: 8.00" wide x 10.00" long x 3.00" tall
Weight: 9.548
Language: English

Contributorsp. xi
Consultants to the Editorsp. xvii
Prefacep. xxi
Preface to the First Editionp. xxiii
General Principlesp. 1
Pharmacokinetics and Pharmacodynamics: The Dynamics of Drug Absorption, Distribution, Action, and Eliminationp. 1
Membrane Transporters and Drug Responsep. 41
Drug Metabolismp. 71
Pharmacogeneticsp. 93
The Science of Drug Therapyp. 117
Drugs Acting at Synaptic and Neuroeffector Junctional Sitesp. 137
Neurotransmission: The Autonomic and Somatic Motor Nervous Systemsp. 137
Muscarinic Receptor Agonists and Antagonistsp. 183
Anticholinesterase Agentsp. 201
Agents Acting at the Neuromuscular Junction and Autonomic Gangliap. 217
Adrenergic Agonists and Antagonistsp. 237
5-Hydroxytryptamine (Serotonin): Receptor Agonists and Antagonistsp. 297
Drugs Acting on the Central Nervous Systemp. 317
Neurotransmission and the Central Nervous Systemp. 317
General Anestheticsp. 341
Local Anestheticsp. 369
Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Heliump. 387
Hypnotics and Sedativesp. 401
Drug Therapy of Depression and Anxiety Disordersp. 429
Pharmacotherapy of Psychosis and Maniap. 461
Pharmacotherapy of the Epilepsiesp. 501
Treatment of Central Nervous System Degenerative Disordersp. 527
Opioid Analgesicsp. 547
Ethanolp. 591
Drug Addiction and Drug Abusep. 607
Autacoids: Drug Therapy of Inflammationp. 629
Histamine, Bradykinin, and Their Antagonistsp. 629
Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factorp. 653
Analgesic-Antipyretic Agents; Pharmacotherapy of Goutp. 671
Pharmacotherapy of Asthmap. 717
Drugs Affecting Renal and Cardiovascular Functionp. 737
Diureticsp. 737
Vasopressin and Other Agents Affecting the Renal Conservation of Waterp. 771
Renin and Angiotensinp. 789
Treatment of Myocardial Ischemiap. 823
Therapy of Hypertensionp. 845
Pharmacotherapy of Congestive Heart Failurep. 869
Antiarrhythmic Drugsp. 899
Drug Therapy for Hypercholesterolemia and Dyslipidemiap. 933
Drugs Affecting Gastrointestinal Functionp. 967
Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Diseasep. 967
Treatment of Disorders of Bowel Motility and Water Flux; Antiemetics; Agents Used in Biliary and Pancreatic Diseasep. 983
Pharmacotherapy of Inflammatory Bowel Diseasep. 1009
Chemotherapy of Parasitic Infectionsp. 1021
Chemotherapy of Protozoal Infections: Malariap. 1021
Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infectionsp. 1049
Chemotherapy of Helminth Infectionsp. 1073
Chemotherapy of Microbial Diseasesp. 1095
General Considerations of Antimicrobial Therapyp. 1095
Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infectionsp. 1111
Penicillins, Cephalosporins, and Other [beta]-Lactam Antibioticsp. 1127
Aminoglycosidesp. 1155
Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agentsp. 1173
Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosyp. 1203
Antifungal Agentsp. 1225
Antiviral Agents (Nonretroviral)p. 1243
Antiretroviral Agents and Treatment of HIV Infectionp. 1273
Chemotherapy of Neoplastic Diseasesp. 1315
Antineoplastic Agentsp. 1315
Immunomodulatorsp. 1405
Immunosuppressants, Tolerogens, and Immunostimulantsp. 1405
Drugs Acting on the Blood and the Blood-Forming Organsp. 1433
Hematopoietic Agents: Growth Factors, Minerals, and Vitaminsp. 1433
Blood Coagulation and Anticoagulant, Thrombolytic, and Antiplatelet Drugsp. 1467
Hormones and Hormone Antagonistsp. 1489
Pituitary Hormones and Their Hypothalamic Releasing Factorsp. 1489
Thyroid and Antithyroid Drugsp. 1511
Estrogens and Progestinsp. 1541
Androgensp. 1573
Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormonesp. 1587
Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreasp. 1613
Agents Affecting Mineral Ion Homeostasis and Bone Turnoverp. 1647
Dermatologyp. 1679
Dermatological Pharmacologyp. 1679
Ophthalmologyp. 1707
Ocular Pharmacologyp. 1707
Toxicologyp. 1739
Principles of Toxicology and Treatment of Poisoningp. 1739
Heavy Metals and Heavy-Metal Antagonistsp. 1753
Principles of Prescription Order Writing and Patient Compliancep. 1777
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