| |
| |
Acknowledgments | |
| |
| |
A Note from the Authors | |
| |
| |
Introduction: What's Wrong with Me? | |
| |
| |
| |
Is The Food You Eat Eating You? | |
| |
| |
| |
Normal Digestion | |
| |
| |
The Gastrointestinal (GI) Tract | |
| |
| |
Digestion | |
| |
| |
The Mouth | |
| |
| |
The Stomach | |
| |
| |
One-Way Street | |
| |
| |
The Pancreas | |
| |
| |
The Liver | |
| |
| |
The Small Intestine | |
| |
| |
Absorption | |
| |
| |
Transport | |
| |
| |
Gluten: The Problem Protein | |
| |
| |
The Colon (Large Intestine) | |
| |
| |
When Normal Goes Pathological | |
| |
| |
In Summary | |
| |
| |
| |
The Digestive Tract in Flames: Celiac Disease | |
| |
| |
Celiac Disease | |
| |
| |
What Is Gluten? | |
| |
| |
What Goes Wrong: The Role of Inflammation | |
| |
| |
What Is Tissue Transglutaminase (tTG)? | |
| |
| |
The Intestinal Battlefield | |
| |
| |
The Digestive Tract in Flames | |
| |
| |
| |
How Does Celiac Disease Affect You? | |
| |
| |
Severe or "Classic" | |
| |
| |
Atypical Celiac Disease | |
| |
| |
Silent Celiac Disease | |
| |
| |
Every Body Reacts Differently | |
| |
| |
Intestinal Problems | |
| |
| |
The Manifestations of Malabsorption | |
| |
| |
Systemic Inflammatory Reactions and Autoimmune Diseases | |
| |
| |
Malignancies | |
| |
| |
| |
How Do I Know If I Have It? The Diagnosis of Celiac Disease | |
| |
| |
Food Allergy versus Gluten Intolerance versus Food or Gluten Sensitivity | |
| |
| |
The Diagnosis | |
| |
| |
Latent Celiac Disease | |
| |
| |
Blood Tests | |
| |
| |
Sensitivity and Specificity | |
| |
| |
IgA Endomysial Antibodies (EMA) | |
| |
| |
IgA Tissue Transglutaminase (tTG) | |
| |
| |
IgA and IgG Antigliadin Antibodies (AGA) | |
| |
| |
Selective IgA Deficiency | |
| |
| |
Laboratory Differences | |
| |
| |
False Negatives/False Positives | |
| |
| |
Endoscopy and Biopsy (the Gold Standard for Diagnosis) | |
| |
| |
How Specific Is a Biopsy | |
| |
| |
Skin Biopsy | |
| |
| |
Gluten Challenge | |
| |
| |
Blood Dot Test | |
| |
| |
Fecal Test | |
| |
| |
Saliva Testing | |
| |
| |
Breath Tests | |
| |
| |
The Future of Testing | |
| |
| |
| |
Differential Diagnosis: Why Is Celiac Disease Underdiagnosed? | |
| |
| |
What Is the Differential Diagnosis of Celiac Disease? | |
| |
| |
You Think You Are Sick, the Doctor Does Not | |
| |
| |
Finding a Doctor | |
| |
| |
Finding the Right Umbrella | |
| |
| |
| |
Why Do People Get Celiac Disease? | |
| |
| |
A Brief History | |
| |
| |
The Crucial Pieces of the Puzzle | |
| |
| |
A Genetic Primer-Fitting the Groove | |
| |
| |
The Swedish Epidemic | |
| |
| |
What We Know | |
| |
| |
We Are Not There Yet | |
| |
| |
| |
Related Conditions and Complications | |
| |
| |
| |
Neurological Manifestations | |
| |
| |
The Nervous System 101 | |
| |
| |
Peripheral Neuropathy | |
| |
| |
Nerve Conduction Studies (EMG) | |
| |
| |
Ataxia | |
| |
| |
Epilepsy | |
| |
| |
Cerebral Calcifications: A Recognition Factor for Celiac Disease | |
| |
| |
Migraines | |
| |
| |
Other Neurological Conditions | |
| |
| |
Paralysis | |
| |
| |
What Causes Neuropathies in Celiac Disease? | |
| |
| |
The Effect of the Gluten-Free Diet | |
| |
| |
| |
Malignancy | |
| |
| |
The Relationship of Malignancies and Celiac Disease: What Is the Risk? | |
| |
| |
What Causes the Cancers? | |
| |
| |
Management Issues | |
| |
| |
The Effect of the Gluten-Free Diet | |
| |
| |
Should I Be Screened for Cancers? | |
| |
| |
| |
Osteoporosis | |
| |
| |
Bones 101 | |
| |
| |
Remodeling the Skeleton | |
| |
| |
The Reservoir Runs Dry | |
| |
| |
Are You at Risk? | |
| |
| |
What Causes Bone Loss in Celiac Disease? | |
| |
| |
Management Issues | |
| |
| |
Tests | |
| |
| |
The Effect of the Gluten-Free Diet | |
| |
| |
Diet and Supplements | |
| |
| |
Bone Resorption Agents | |
| |
| |
Parathyroid Hormone (PTH) | |
| |
| |
Exercise | |
| |
| |
| |
Depression | |
| |
| |
What Is Depression? | |
| |
| |
What Causes Depression in Celiac Disease? | |
| |
| |
Nutrient Malabsorption-Folic Acid | |
| |
| |
The Effect of the Gluten-Free Diet | |
| |
| |
The Bottom Line | |
| |
| |
| |
Dermatitis Herpetiformis and Other Skin Diseases | |
| |
| |
What Is Dermatitis Herpetiformis? | |
| |
| |
How Do I Know If I Have It-Tests for Dermatitis Herpetiformis | |
| |
| |
Where Does It Come From-Pathogenesis | |
| |
| |
Dermatitis Herpetiformis and Other Diseases | |
| |
| |
Brusing | |
| |
| |
Management Issues | |
| |
| |
Systemic Drugs | |
| |
| |
Topical Creams | |
| |
| |
What Triggers Dermatitis Herpetiformis? | |
| |
| |
The Effect of the Gluten-Free Diet | |
| |
| |
Hiding in Plain Sight | |
| |
| |
Other Skin Conditions | |
| |
| |
| |
Diabetes | |
| |
| |
What Is Diabetes? | |
| |
| |
What Causes Type 1 Diabetes (IDDM)? | |
| |
| |
Diabetes and Celiac Disease | |
| |
| |
Management Issues | |
| |
| |
Lifestyle and Compliance Issues | |
| |
| |
Will I Get Better on a Gluten-Free Diet? | |
| |
| |
To Test or Not to Test | |
| |
| |
| |
Infertility | |
| |
| |
What Causes Infertility? | |
| |
| |
The Relationship to Celiac Disease: Effect on Females | |
| |
| |
The Relationship to Celiac Disease: Effect on Males | |
| |
| |
What Causes Infertility in Celiac Disease? | |
| |
| |
The Effect of the Gluten-Free Diet | |
| |
| |
Next Steps | |
| |
| |
| |
Autoimmune and Other Related Conditions | |
| |
| |
What Causes Autoimmune Disease? | |
| |
| |
Which Comes First? | |
| |
| |
Thyroid Disease | |
| |
| |
Sjogren's Syndrome | |
| |
| |
Addison's Disease | |
| |
| |
Autoimmune Liver Disease | |
| |
| |
Cardiomyopathy | |
| |
| |
Alopecia Areata | |
| |
| |
Lupus | |
| |
| |
Rheumatoid Arthritis | |
| |
| |
Fibromyalgia | |
| |
| |
Aphthous Stomatitis | |
| |
| |
Multiple Sclerosis (MS) | |
| |
| |
Attention-Deficit/Hyperactivity Disorder (ADHD)/Autism Spectrum Disorder (ASD) | |
| |
| |
Dental Enamel Defects | |
| |
| |
Raynaud's Syndrome | |
| |
| |
Genetic Disorders | |
| |
| |
A Final Word | |
| |
| |
| |
Understanding and Treating Celiac Disease: Medical Management | |
| |
| |
| |
What You Need to Know-and Do-After Diagnosis | |
| |
| |
Treating the Patient, Not the Refrigerator | |
| |
| |
Dietary Counseling About the Gluten-Free Diet | |
| |
| |
Assessment of Nutritional Deficiencies | |
| |
| |
Medication Assessment | |
| |
| |
Bone Density Determination | |
| |
| |
Pneumovax Vaccination | |
| |
| |
Screening of Family Members | |
| |
| |
Monitoring of Blood Antibody Levels | |
| |
| |
Repeat of Biopsy | |
| |
| |
Screening for Malignancies | |
| |
| |
General Health Measures | |
| |
| |
| |
Why Symptoms Persist-I'm on the Diet and Not Getting Better | |
| |
| |
Lactose Intolerance | |
| |
| |
Pancreatic Insufficiency | |
| |
| |
Bacterial Overgrowth | |
| |
| |
Microscopic Colitis | |
| |
| |
Refractory Sprue | |
| |
| |
Skin Manifestations | |
| |
| |
How Soon Will I Get Better? | |
| |
| |
| |
Follow-Up Testing | |
| |
| |
Follow-Up Blood Tests | |
| |
| |
Follow-Up Biopsy | |
| |
| |
Family Testing | |
| |
| |
High-Risk Group Testing | |
| |
| |
Genetic Testing | |
| |
| |
Video Capsule Endoscopy | |
| |
| |
| |
The Diet: Do You Eat to Live or Live to Eat? | |
| |
| |
| |
What Living Gluten-Free Really Means: The Basics | |
| |
| |
How Much Is Too Much? | |
| |
| |
Grain Science | |
| |
| |
Cross Contamination | |
| |
| |
Basic Rules for Avoiding Cross Contamination | |
| |
| |
Are You Getting Good Information? | |
| |
| |
| |
Reading Labels | |
| |
| |
The 2004 Labeling Law | |
| |
| |
Labels 101 | |
| |
| |
Ingredients and Additives Worth Understanding | |
| |
| |
Gluten-Free Labels by 2008 | |
| |
| |
Testing for Gluten in a Product | |
| |
| |
Labels-The Next Steps | |
| |
| |
Questions That Remain | |
| |
| |
| |
Cooking Without Gluten | |
| |
| |
Cooking Styles | |
| |
| |
Cooking Gluten-Free | |
| |
| |
| |
Eating in the Real World | |
| |
| |
Restaurants | |
| |
| |
"Back-Home" Techniques | |
| |
| |
A Brief Sauce Primer | |
| |
| |
Other People's Homes | |
| |
| |
Hospital Stays | |
| |
| |
Travel | |
| |
| |
| |
Family Occasions | |
| |
| |
Holidays-Dealing with the Urge to Splurge | |
| |
| |
Banquets and Wedding Bell Blues | |
| |
| |
| |
The Medicine Cabinet and Cosmetics | |
| |
| |
Prescription Drugs | |
| |
| |
Vitamins, Minerals, and Other Supplements | |
| |
| |
Wheatgrass | |
| |
| |
Toothpaste | |
| |
| |
Cosmetics | |
| |
| |
| |
Eating Naked | |
| |
| |
Is Your Gluten-Free Diet Keeping You Healthy? | |
| |
| |
Cholesterol/Triglycerides | |
| |
| |
Children at Risk | |
| |
| |
| |
Living with | |
| |
| |
| |
Dealing with Children and Young Adults Who Have Celiac Disease | |
| |
| |
Factors That Affect Successful Adaptation | |
| |
| |
Parental Attitudes | |
| |
| |
The First Five (Birth to Five Years Old) | |
| |
| |
Six Ups (Six to Eleven Years Old) | |
| |
| |
Twelve Ups (Twelve to Eighteen Years Old, Adolescents) | |
| |
| |
Adolescents with Celiac Disease and Type 1 Diabetes (IDDM) | |
| |
| |
Young Adults (College and Up) | |
| |
| |
Road Rules | |
| |
| |
| |
Adults: Coping with Change | |
| |
| |
Reactions to the Diagnosis | |
| |
| |
Dealing with "Forbidden Fruit" | |
| |
| |
Passing the Pizza Test | |
| |
| |
Helpful Hints | |
| |
| |
| |
Research: Finding a Cure | |
| |
| |
Potential Therapies | |
| |
| |
Designer Drugs | |
| |
| |
"First, Do No Harm" | |
| |
| |
| |
Myths and Unexplored Areas | |
| |
| |
Myths Surrounding Celiac Disease | |
| |
| |
Unexplored Areas | |
| |
| |
| |
A Guide to Ingredients | |
| |
| |
| |
Explanation of Grains | |
| |
| |
| |
Books and Articles of Interest | |
| |
| |
| |
Medical Contact Information | |
| |
| |
| |
National Support Groups | |
| |
| |
| |
Publications and Resources | |
| |
| |
Glossary | |
| |
| |
Index | |