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Biophysical Chemistry

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ISBN-10: 1849730814

ISBN-13: 9781849730815

Edition: 2nd 2011

Authors: Alan Cooper, J. Derek Woollins, A. G Davies, David Phillips, E. Abel

List price: $21.99
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Book details

List price: $21.99
Edition: 2nd
Copyright year: 2011
Publisher: Royal Society of Chemistry, The
Publication date: 2/23/2011
Binding: Paperback
Pages: 244
Size: 7.44" wide x 9.69" long x 0.60" tall
Weight: 1.034
Language: English

Alan Cooper is a Professor of Biophysical Chemistry in the Chemistry Department at Glasgow University, Glasgow, UK. After obtaining a first class honours degree in physics from Manchester University, he gained a diploma for Advanced Studies in Science (with Distinction) on the calculation of dispersion forces and optical properties of helical polynucleotides and a PhD in Biophysics on the thermodynamics of assembly and stability of collagen - both from Manchester University. Since then he has been a SRC Research Fellow at the Laboratory of Molecular Biophysics, Oxford University and a Junior Research Fellow, Wolfson College, Oxford as well as a NIH Research Fellow on the Pathology of…    

Biological Molecules
Introduction
Proteins and Polypeptides
Polynucleotides
Polysaccharides
Fats, Lipids and Detergents
Water
Foams, Surfactants and Emulsions
Acids, Bases, Buffers and Polyelectrolytes
A Note about Units
Problems
References
Further Reading
Spectroscopy
Electromagnetic Waves and their Interactions
UV/Visible Spectroscopy
Circular Dichroism
Fluorescence
Vibrational Spectroscopy: IR and Raman
NMR (Brief Overview)
Problems
References
Further Reading
Mass Spectrometry
Introduction
Ion Sources
Ionization Methods
Mass Analysers
Detection
Applications of MS
Problems
References
Further Reading
Hydrodynamics
Density and Molecular Volume
Analytical Ultracentrifugation
Sedimentation Equilibrium
Sedimentation Rate
Diffusion and Brownian Motion
Dynamic Light Scattering (DLS)
Viscosity
Problems
References
Further Reading
Thermodynamics and interactions
A Bluffer's Guide to Molecular Thermodynamics
Differential Scanning Calorimetry
Isothermal Titration Calorimetry
Binding Equilibrium
General Methods for Determining Thermodynamic Properties
Thermal Shift Assays
Equilibrium Dialysis
Protein Solubility and Crystallization
Problems
References
Further Reading
Kinetics
Basic Kinetics
Rapid Reaction Techniques
Relaxation Methods
Hydrogen Exchange
Surface Plasmon Resonance
Enzyme Kinetics
Problems
References
Further Reading
Chromatography and Electrophoresis
Chromatography
Electrophoresis
Problems
References
Further Reading
imaging
Waves and Particles
Lenses or No Lenses: Reconstructing the Image
X-ray Diffraction and Protein Crystallography
Fibre Diffraction and Small-angle Scattering
Neutron Diffraction and Scattering
Electron Microscopy
Problems
References
Further Reading
Single Molecules
How Many Molecules can Stand on the Head of a Pin?
Thermodynamic Fluctuations and the Ergodic Hypothesis
Atomic Force Microscopy
Optical Tweezers and Traps
Single Molecule Fluorescence
Problems
References
Further Reading
Answers to Problems
Subject Index