Fundamentals and Applications of Microfluidics

ISBN-10: 1580539726
ISBN-13: 9781580539722
Edition: 2nd 2006
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Description: Updating the Artech House bestseller, Fundamentals and Applications of Microfluidics, this newly revised second edition provides electrical and mechanical engineers with complete and current coverage of microfluidics - an emerging field involving  More...

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Book details

Edition: 2nd
Copyright year: 2006
Publisher: Artech House
Binding: Hardcover
Pages: 497
Size: 7.25" wide x 10.50" long x 1.25" tall
Weight: 2.398
Language: English

Updating the Artech House bestseller, Fundamentals and Applications of Microfluidics, this newly revised second edition provides electrical and mechanical engineers with complete and current coverage of microfluidics - an emerging field involving fluid flow and devices in microscale and nanoscale. The second edition offers a greatly expanded treatment of nanotechnology, electrokinetics and flow theory. The book shows engineers how to take advantage of the performance benefits of microfluidics and serves as an instant reference for state-of-the-art microfluidics technology and applications. The wide range of applications discussed includes fluid control devices, gas and fluid measurement devices, medical testing equipment, and implantable drug pumps. Professionals learn how to choose the best fabrication and enabling technology for a specific microfluidic application.

Nam-Trung Nguyen received his M.Sc. and Ph.D. in electrical engineering from Chemnitz University of Technology, Germany. He is an assistant professor at the School of Mechanical and Production Engineering at Nanyang Technological University.

Preface
Acknowledgments
Introduction
What Is Microfluidics?
Relationships Among MEMS, Nanotechnology, and Microfluidics
Commercial Aspects
Scientific Aspects
Milestones of Microfluidics
Device Development
Technology Development
Organization of the Book
References
Fluid Mechanics Theory
Introduction
Intermolecular Forces
The Three States of Matter
Continuum Assumption
Continuum Fluid Mechanics at Small Scales
Gas Flows
Liquid Flows
Boundary Conditions
Parallel Flows
Low Reynolds Number Flows
Entrance Effects
Surface Tension
Molecular Approaches
MD
DSMC Technique
Electrokinetics
Electro-osmosis
Electrophoresis
Dielectrophoresis
Conclusion
Problems
References
Fabrication Techniques for Microfluidics
Basic Microtechniques
Photolithography
Additive Techniques
Subtractive Techniques
Pattern Transfer Techniques
Functional Materials
Materials Related to Silicon Technology
Polymers
Silicon-Based Micromachining Techniques
Silicon Bulk Micromachining
Silicon Surface Micromachining
Polymer-Based Micromachining Techniques
Thick Resist Lithography
Polymeric Bulk Micromachining
Polymeric Surface Micromachining
Microstereo Lithography
Micromolding
Other Micromachining Techniques
Subtractive Techniques
Additive Techniques
Assembly and Packaging of Microfluidic Devices
Wafer Level Assembly and Packaging
Device Level Packaging
Biocompatibility
Material Response
Tissue and Cellular Response
Biocompatibility Tests
Problems
References
Experimental Flow Characterization
Introduction
Pointwise Methods
Full-Field Methods
Overview of [mu]PIV
Fundamental Physics Considerations of [mu]PIV
Special Processing Methods for [mu]PIV Recordings
Advanced Processing Methods Suitable for Both Micro/Macro-PIV Recordings
[mu]PIV Examples
Flow in a Microchannel
Flow in a Micronozzle
Flow Around a Blood Cell
Flow in Microfluidic Biochip
Conclusions
Extensions of the [mu]PIV Technique
Microfluidic Nanoscope
Microparticle Image Thermometry
Infrared [mu]PIV
Particle Tracking Velocimetry
Problems
References
Microfluidics for External Flow Control
Velocity and Turbulence Measurement
Velocity Sensors
Shear Stress Sensors
Turbulence Control
Microflaps
Microballoon
Microsynthetic Jet
Microair Vehicles
Fixed-Wing MAV
Flapping-Wing MAV
Microrotorcraft
Microrockets
Problems
References
Microfluidics for Internal Flow Control: Microvalves
Design Considerations
Actuators
Valve Spring
Valve Seat
Pressure Compensation Design
Design Examples
Pneumatic Valves
Thermopneumatic Valves
Thermomechanical Valves
Piezoelectric Valves
Electrostatic Valves
Electromagnetic Valves
Electrochemical and Chemical Valves
Capillary-Force Valves
Summary
Problems
References
Microfluidics for Internal Flow Control: Micropumps
Design Considerations
Mechanical Pumps
Nonmechanical Pumps
Design Examples
Mechanical Pumps
Nonmechanical Pumps
Summary
Problems
References
Microfluidics for Internal Flow Control: Microflow Sensors
Design Considerations
Design Parameters
Nonthermal Flow Sensors
Thermal Flow Sensors
Design Examples
Nonthermal Flow Sensors
Thermal Flow Sensors
Summary
Problems
References
Microfluidics for Life Sciences and Chemistry: Microneedles
Design Considerations
Mechanical Design
Delivery Modes
Design Examples
Solid Microneedles
Hollow Microneedles
Summary
Problems
References
Microfluidics for Life Sciences and Chemistry: Micromixers
Design Considerations
Parallel Lamination
Sequential Lamination
Sequential Segmentation
Segmentation Based on Injection
Focusing of Mixing Streams
Formation of Droplets and Chaotic Advection
Design Examples
Passive Micromixers
Active Micromixers
Summary
Problems
References
Microfluidics for Life Sciences and Chemistry: Microdispensers
Design Considerations
Droplet Dispensers
In-Channel Dispensers
Design Examples
Droplet Dispensers
In-Channel Dispensers
Summary
Problems
References
Microfluidics for Life Sciences and Chemistry: Microfilters and Microseparators
Microfilters
Design Considerations
Design Examples
Microseparator
Cell and Particle Sorter
Chromatography
Summary
Problems
References
Microfluidics for Life Sciences and Chemistry: Microreactors
Design Considerations
Specification Bases for Microreactors
Miniaturization of Chemical Processes
Functional Elements of a Microreactor
Design Examples
Gas-Phase Reactors
Liquid-Phase Reactors
Multiphase Reactors
Microreactors for Cell Treatment
Hybridization Arrays
Summary
Problems
References
List of Symbols
Resources for Microfluidics Research
Abbreviations of Different Plastics
Linear Elastic Deflection Models
About the Authors
Index

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