| |
| |
| Contributors | |
| |
| |
| Foreword | |
| |
| |
| Preface | |
| |
| |
| Acknowledgments | |
| |
| |
| A Website Companion for Scientific Integrity: Text and Cases in Responsible Conduct of Research, Third Edition | |
| |
| |
| Note to Students and Instructors | |
| |
| |
| |
| Methods, Manners, and the Responsible Conduct of Research | |
| |
| |
| |
| Overview | |
| |
| |
| Scientific Misconduct | |
| |
| |
| Responsible Conduct of Research | |
| |
| |
| Conclusion | |
| |
| |
| Discussion Questions | |
| |
| |
| References | |
| |
| |
| Resources | |
| |
| |
| |
| Ethics and the Scientist | |
| |
| |
| |
| Overview | |
| |
| |
| Ethics and The Scientist | |
| |
| |
| Underlying Philosophical Issues | |
| |
| |
| Utilitarianism | |
| |
| |
| Deontology | |
| |
| |
| Critical Thinking and the Case Study Approach | |
| |
| |
| Moral Reasoning in the Conduct of Science | |
| |
| |
| Conclusion | |
| |
| |
| Discussion Questions | |
| |
| |
| Case Studies | |
| |
| |
| References | |
| |
| |
| Resources | |
| |
| |
| |
| Mentoring | |
| |
| |
| |
| Overview | |
| |
| |
| Characteristics of the Mentor-Trainee Relationship | |
| |
| |
| Selection of a Mentor | |
| |
| |
| Mentoring Guidelines | |
| |
| |
| Conclusion | |
| |
| |
| Discussion Questions | |
| |
| |
| Case Studies | |
| |
| |
| References | |
| |
| |
| Resources | |
| |
| |
| |
| Authorship and Peer Review | |
| |
| |
| |
| Scientific Publication and Authorship | |
| |
| |
| The Pressure to Publish | |
| |
| |
| The Need for Authorship Criteria | |
| |
| |
| Instructions to Authors | |
| |
| |
| Guidelines for Authorship | |
| |
| |
| Peer Review | |
| |
| |
| The Workings of Peer Review | |
| |
| |
| Being a Peer Reviewer | |
| |
| |
| Emerging Trends and Policies | |
| |
| |
| Conclusion | |
| |
| |
| Discussion Questions | |
| |
| |
| Case Studies | |
| |
| |
| Resources | |
| |
| |
| |
| Use of Humans in Biomedical Experimentation | |
| |
| |
| |
| Overview | |
| |
| |
| Are You Conducting Human Subject Research? | |
| |
| |
| The Issue of Informed Consent | |
| |
| |
| Institutional Review Boards | |
| |
| |
| The Institutional Review Board and the Informed Consent Issue | |
| |
| |
| The Institutional Review Board and Expedited Review | |
| |
| |
| Human Experimentation Involving Special Populations | |
| |
| |
| The Health Insurance Portability and Accountability Act (HIPAA) | |
| |
| |
| Fetal Tissue and Embryonic Stem Cell Research | |
| |
| |
| Conclusion | |
| |
| |
| Discussion Questions | |
| |
| |
| Case Studies | |
| |
| |
| The Declaration of Helsinki | |
| |
| |
| References | |
| |
| |
| Resources | |
| |
| |
| |
| Use of Animals in Biomedical Experimentation | |
| |
| |
| |
| Introduction | |
| |
| |
| Ethical Challenges to the Use of Animals in Research | |
| |
| |
| Practical Matters: Constraints on the Behavior of Scientists | |
| |
| |
| Political Realities: Then and Now | |
| |
| |
| Discussion Questions | |
| |
| |
| Case Studies | |
| |
| |
| References | |
| |
| |
| Resources | |
| |
| |
| |
| Managing Competing Interests | |
| |
| |
| |
| Introduction | |
| |
| |
| Conflict of Effort | |
| |
| |
| Conflict of Conscience | |
| |
| |
| Conflict of Interest | |
| |
| |
| Managing Competing Interests | |
| |
| |
| Conclusion | |
| |
| |
| Discussion Questions | |
| |
| |
| Case Studies | |
| |
| |
| Resources | |
| |
| |
| |
| Collaborative Research | |
| |
| |
| |
| Overview | |
| |
| |
| The Nature of Collaboration | |
| |
| |
| A Syllabus of Collaboration Principles | |
| |
| |
| Collaboration Models | |
| |
| |
| Conclusion | |
| |
| |
| Discussion Questions | |
| |
| |
| Case Studies | |
| |
| |
| References | |
| |
| |
| Resources | |
| |
| |
| |
| Ownership of Data and Intellectual Property | |
| |
| |
| |
| Introduction | |
| |
| |
| Review of Ownership of Research Data | |
| |
| |
| Rights in Tangible Personal Property | |
| |
| |
| Trade Secrets | |
| |
| |
| Trademarks | |
| |
| |
| Copyrights | |
| |
| |
| Patents | |
| |
| |
| Patent Law in the Age of Biotechnology | |
| |
| |
| Seeking a Patent | |
| |
| |
| Conclusion | |
| |
| |
| Discussion Questions | |
| |
| |
| Case Studies | |
| |
| |
| Author's Note | |
| |
| |
| Resources | |
| |
| |
| Glossary | |
| |
| |
| |
| Genetic Technology and Scientific Integrity | |
| |
| |
| |
| Introduction | |
| |
| |
| Genetic Screening and Diagnosis | |
| |
| |
| The Human Genome Project | |
| |
| |
| Manipulating Genes | |
| |
| |
| Conclusion | |
| |
| |
| Discussion Questions | |
| |
| |
| Case Studies | |
| |
| |
| References | |
| |
| |
| Resources | |
| |
| |
| |
| Scientific Record Keeping | |
| |
| |
| |
| Introduction | |
| |
| |
| Why Do We Keep Records? | |
| |
| |
| Defining Data | |
| |
| |
| Data Ownership | |
| |
| |
| Data Storage and Retention | |
| |
| |
| Tools of the Trade | |
| |
| |
| Laboratory Record-Keeping Policies | |
| |
| |
| Suggestions for Record Keeping | |
| |
| |
| Electronic Record Keeping | |
| |
| |
| Conclusion | |
| |
| |
| Discussion Questions | |
| |
| |
| Case Studies | |
| |
| |
| References | |
| |
| |
| Resources | |
| |
| |
| |
| Surveys as a Tool for Training in Scientific Integrity | |
| |
| |
| |
| |
| Student Exercises | |
| |
| |
| |
| Standards of Conduct | |
| |
| |
| |
| Sample Protocols for Human and Animal Experimentation | |
| |
| |
| |
| Example of a U.S. Patent Specification | |
| |
| |
| |
| Laboratory Notebook Instructions | |
| |
| |
| Index | |