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Microbial DNA and Host Immunity

ISBN-10: 1468497286
ISBN-13: 9781468497281
Edition: 2002
Authors: Eyal Raz
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Description: Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the  More...

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Book details

Copyright year: 2002
Publisher: Humana Press
Publication date: 10/8/2012
Binding: Paperback
Pages: 408
Size: 6.10" wide x 9.25" long
Weight: 1.430
Language: English

Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS, the process of cell activation, and the potential vaccination strategies using ISS. Specific pharmaceutical applications discussed include infectious disease (Hepatitis B, HIV, and mycobacterial infections), allergy (asthma and conjunctivitis), cancer (lymphoma), and inflammation and autoimmunity (arthritis and colitis).

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