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Third edition editorial board | |
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Contributors | |
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Acknowledgements | |
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Preface | |
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Introduction | |
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Overview | |
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Organisation of information in the Guide | |
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Sources of information and disclaimer | |
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UCLH policies | |
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Responsibilities of professional staff at UCLH | |
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Preparation of injectable medicines on wards, clinics and departments at UCLH | |
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An overview of intravenous therapy | |
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When is intravenous therapy appropriate? | |
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Drug factors that influence the choice of route | |
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Disadvantages of intravenous administration | |
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Route of intravenous administration | |
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Factors affecting patency of IV sites | |
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Factors increasing failure of IV sites | |
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Factors decreasing failure of IV sites | |
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Occlusion of central venous catheters | |
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Methods of intravenous administration | |
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Intravenous bolus | |
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Intermittent intravenous infusion | |
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Continuous intravenous infusion | |
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Preparation and administration of intravenous medicines | |
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Aseptic non-touch technique (ANTT) | |
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Extravasation of injectables: overview and management advice | |
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Patient factors affecting extravasation | |
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Medicine factors affecting extravasation | |
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Administration factors affecting extravasation | |
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Overall risk for extravasation | |
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Treatment of extravasation | |
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Flushing cannulae, catheters and administration sets | |
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Flushing between medicines | |
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When not to flush | |
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Flushing catheters and cannulae not in use | |
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Flushing with heparin | |
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Infusion pumps | |
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Pumps used at UCLH | |
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Volumetric pumps | |
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Syringe pumps | |
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Pumps for ambulatory use | |
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Patient-controlled analgesia (PCA) pumps | |
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Target-controlled anaesthesia (TCI or TIVA) pumps | |
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Administration of injectables in primary care | |
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Self-caring patients | |
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Formulation and presentation of injectables | |
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Medicines that require reconstitution | |
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Preparations in solution requiring further dilution before use | |
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Preparations available 'ready to use' without further dilution | |
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Preparations available 'ready to use' | |
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Pharmaceutical aspects of injectable administration | |
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Displacement values | |
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Sodium content | |
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Drop size | |
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Layering | |
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Fluid restriction | |
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Factors influencing medicine stability and compatibility of injectable medicines | |
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Degradation | |
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Precipitation | |
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Binding of medicines to plastics | |
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Destabilisation of parenteral emulsions | |
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Leaching of plasticisers | |
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Blood and blood products | |
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Allergic reactions to injectables | |
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Latex allergy | |
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Compatibility of drugs in a syringe driver for subcutaneous use | |
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Risk assessment of injectables and risk reduction | |
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Risk assessment | |
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Risk reduction | |
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Useful resources | |
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Websites | |
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Further reading | |
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User Guide | |
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Monographs in alphabetical order | |
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Index | |