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Preface | |
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Acknowledgements | |
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The basics of cancer | |
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Cancer is a complex entity | |
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Cancer through the ages | |
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Modem day cancer research and treatment | |
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Prevalence and mortality varies with each cancer | |
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Risk factors have been identified | |
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Will cancer be conquered within our lifetime? | |
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Cells: The fundamental unit of life | |
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Seven hierarchal levels of organization | |
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Four types of macromolecular polymers | |
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Cell structure and function | |
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Relationship between structure and function is important | |
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The human genome and protein function | |
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The composition and function of the human genome | |
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Having a diploid genome has its advantages | |
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Proteins carry out diverse functions | |
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Cell cycle, oncogenes, and tumor suppressor genes | |
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Cell division in germ-line and somatic tissues | |
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Consequences of germ-line and somatic tissue mutations | |
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Cell division, differentiation, and maturation occur to form functional tissues | |
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Cell division is under the regulation of the cell cycle | |
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Loss of cell cycle control results in uncontrolled cell growth | |
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Tumor formation, growth, and metastasis | |
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Tissue changes that occur in response to stimuli | |
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Feeding tumor growth by angiogenesis | |
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Characteristics of benign and malignant tumors | |
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Events that occur during the process of metastasis | |
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Cancer screening, detection and diagnostic procedures and tests | |
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Factors that determine the accuracy of a diagnostic test or procedure | |
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Common screening tests | |
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Diagnostic procedures for the confirmation of a disease | |
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Tumor grade and stage factor into the type of treatment regimen and prognosis | |
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Cancer treatment modalities | |
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Surgery: the oldest and most commonly used treatment method | |
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Radiation kills by causing extensive DNA damage | |
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Cytotoxic effects of chemotherapeutic drugs | |
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Side effects and risks from the use of cytotoxic drugs | |
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Hormonal deprivation treatment: used for estrogen- and androgen-dependent cancers | |
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Can cancer growth be controlled by inhibiting angiogenesis? | |
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Additional enzymes targeted for inhibition | |
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Biological therapy stimulates the body's ability to fight cancer | |
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Breast cancer | |
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Breast cancer statistics | |
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Women's breast tissue: unique in structure and function | |
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Causes of breast cancer | |
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Regular examinations of the breast are important for early diagnosis | |
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What follows a positive diagnosis? | |
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Treatment options are unique for each individual | |
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Much has been accomplished, more needs to be done | |
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Ovarian cancer | |
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Ovarian cancer statistics | |
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Structure and function of ovaries | |
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There are three tissue categories of ovarian cancer | |
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Symptoms of overian cancer are vague and often missed | |
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Certain factors have been associated with a higher risk | |
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Diagnostic tools are available but not always used or recommended | |
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Additional procedures are necessary to confirm suspicious results or if there is metastasis | |
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The FIGO system may be used to stage ovarian cancer | |
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Treatment options for ovarian cancer | |
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Steps are taken to prevent recurrence but do not always work when the cancer is advanced | |
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Much needs to be done in the future | |
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Cervical cancer | |
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Cervical cancer statistics | |
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Structure and function of the cervix | |
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Symptoms of cervical cancer | |
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Pelvic examinations and Pap tests enable early detection | |
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Risk factors for cervical cancer | |
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The HPV test is a vital diagnostic tool | |
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Additional tests are necessary to examine the cervix | |
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Treatment depends on the stage | |
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A vaccine will prevent many cases of cervical cancer | |
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Prostate cancer | |
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Prostate cancer statistics | |
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Function of the prostate gland | |
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Certain factors influence the development of prostate cancer | |
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Symptoms of an enlarged prostate | |
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Screening and diagnostic tests for prostate cancer | |
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There are traditional and unique treatment options available | |
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Prostate cancer mortality rates have decreased | |
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Much attention is being given to the number one cancer affecting men | |
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Testicular cancer | |
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Testicular cancer statistics | |
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Structure and function of testicles | |
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There are three types of testicular tumors | |
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Risk factors for the disease | |
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Symptoms of testicular cancer | |
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Testicular self-examination (TSE) is recommended | |
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Blood and imaging tests are used to determine diagnosis and possible metastasis | |
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Testicular cancer treatment results in a high cure rate | |
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Causes and treatments are being studied | |
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Skin cancer | |
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Skin cancer statistics | |
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Structure and function of the skin | |
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Three types of skin cancer | |
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Risk factors for developing skin cancer | |
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Methods used to screen for skin cancer | |
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Surgery and chemotherapy are standard treatments for metastatic skin cancer | |
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What happens after skin cancer treatment | |
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Limited UV radiation exposure is the number one form of prevention | |
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Lung cancer | |
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Lung cancer statistics | |
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Lungs are the site of the exchange of gases | |
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Risk factors associated with the development of lung cancer | |
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Lack of distinctive symptoms makes early diagnosis difficult | |
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Lung cancer is often diagnosed at an advanced stage | |
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There are two main categories of lung cancer | |
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Three traditional therapies are used in lung cancer treatment | |
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Is there discrimination in cancer research funding? | |
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Colorectal cancer | |
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Colon and rectum are the last two sections of the gastrointestinal tract | |
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Risk factors for colorectal cancer | |
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Screening tests | |
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Treatment options | |
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Targeted therapies | |
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Screening tests performed after the course of treatment | |
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Leukemia and lymphoma | |
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Leukemia statistics | |
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Leukemia is a cancer of the blood cells | |
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The exact cause of leukemia is unknown | |
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Early symptoms of leukemia | |
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Laboratory studies are necessary to determine the diagnosis | |
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There are many types of leukemia | |
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Nonchemotherapeutic treatment options have significantly improved survival rates | |
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Lymphoma is a malignancy of the lymphatic system | |
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Hodgkin's vs. non-Hodgkin's lymphoma | |
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Certain risk factors are associated with an increased incidence of lymphoma | |
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Diagnosing lymphoma involves biopsies and imaging tests | |
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Lymphomas must be classified to determine appropriate treatment | |
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Treatment options depend on the type of lymphoma, stage, and extent of metastasis | |
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Glossary | |
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Index | |