| |
| |
Preface | |
| |
| |
Sources of illustrations | |
| |
| |
Introduction | |
| |
| |
| |
Overview of the cardiovascular system | |
| |
| |
Anatomy and histology | |
| |
| |
| |
Gross anatomy and histology of the heart | |
| |
| |
| |
Vascular anatomy | |
| |
| |
| |
Vascular histology and smooth muscle cell ultrastructure | |
| |
| |
Blood and body fluids | |
| |
| |
| |
Constituents of blood | |
| |
| |
| |
Erythropoiesis, haemoglobin and anaemia | |
| |
| |
| |
Haemostasis and thrombosis | |
| |
| |
| |
Blood groups and transfusions | |
| |
| |
Biochemistry and cellular physiology | |
| |
| |
| |
Membrane potential, ion channels and pumps | |
| |
| |
| |
Electrophysiology of cardiac muscle and origin of the heart beat | |
| |
| |
| |
Excitation-contraction coupling in cardiac muscle cells | |
| |
| |
| |
Vascular smooth muscle excitation-contraction coupling | |
| |
| |
Form and function | |
| |
| |
| |
Cardiac cycle | |
| |
| |
| |
Control of cardiac output and Starling's Law of the Heart | |
| |
| |
| |
Electrical conduction system in the heart | |
| |
| |
| |
The electrocardiogram | |
| |
| |
| |
Haemodynamics | |
| |
| |
| |
Blood pressure and flow in the arteries and arterioles | |
| |
| |
| |
The microcirculation and lymphatic system | |
| |
| |
| |
Fluid filtration in the microcirculation | |
| |
| |
| |
The venous system | |
| |
| |
| |
Local control of bloodflow | |
| |
| |
| |
Regulation of the vasculature by the endothelium | |
| |
| |
| |
The coronary, skeletal muscle, cutaneous and cerebral circulations | |
| |
| |
| |
The pulmonary and fetal circulations | |
| |
| |
Integration and regulation | |
| |
| |
| |
Cardiovascular reflexes | |
| |
| |
| |
Autonomic control of the cardiovascular system | |
| |
| |
| |
The control of blood volume | |
| |
| |
| |
Cardiovascular effects of exercise | |
| |
| |
| |
Shock and haemorrhage | |
| |
| |
Pathology and therapeutics | |
| |
| |
| |
Risk factors for cardiovascular disease | |
| |
| |
| |
Clinical measurement of cardiac and vascular function | |
| |
| |
| |
Hyperlipidaemias | |
| |
| |
| |
Atherosclerosis | |
| |
| |
| |
Treatment of hypertension | |
| |
| |
| |
Mechanisms of primary hypertension | |
| |
| |
| |
Stable and variant angina | |
| |
| |
| |
Unstable angina and non-ST segment elevation myocardial infarction | |
| |
| |
| |
Pharmacological management of stable and variant angina | |
| |
| |
| |
Revascularization | |
| |
| |
| |
Pathophysiology of acute myocardial infarction | |
| |
| |
| |
Clinical aspects of acute myocardial infarction | |
| |
| |
| |
Anticoagulants and thrombolytics | |
| |
| |
| |
Chronic heart failure | |
| |
| |
| |
Treatment of chronic heart failure | |
| |
| |
| |
Mechanisms of arrhythmia | |
| |
| |
| |
Pharmacological treatment of arrhythmias | |
| |
| |
| |
Specific arrhythmias | |
| |
| |
| |
Diseases of the aortic valve | |
| |
| |
| |
Diseases of the mitral valve | |
| |
| |
| |
Congenital heart disease | |
| |
| |
| |
Emerging trends in cardiovascular medicine | |
| |
| |
Case studies: diagnosis, treatment and results | |
| |
| |
| |
Case study: heart failure | |
| |
| |
| |
Case study: valvular heart disease | |
| |
| |
| |
Case study: ischaemic heart disease | |
| |
| |
| |
Case studies: arrhythmias | |
| |
| |
Index | |