Introduction to Cancer Biology

ISBN-10: 1107601487
ISBN-13: 9781107601482
Edition: 2013
Authors: Robin Hesketh
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Description: This concise overview of the fundamental concepts of cancer biology is ideal for those with little or no background in the field. A summary of global cancer patterns introduces students to the general principles of how cancers arise and the risk  More...

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Book details

Copyright year: 2013
Publisher: Cambridge University Press
Publication date: 12/13/2012
Binding: Paperback
Pages: 352
Size: 7.75" wide x 9.75" long x 0.75" tall
Weight: 2.002
Language: English

This concise overview of the fundamental concepts of cancer biology is ideal for those with little or no background in the field. A summary of global cancer patterns introduces students to the general principles of how cancers arise and the risk factors involved. By focusing on fundamental examples of the signalling pathways within cells, the functional effects of DNA damage are explained. Later chapters then build on this foundation to provide a comprehensive summary of the major signalling pathways that affect tumour development. Current therapeutic strategies are reviewed, along with a discussion of methods for tumour detection and biomarker identification. Finally, the impact of whole genome sequencing is discussed, bringing students up to date with key recent developments in the field. From basic principles to insights into cutting-edge research, this book will enable the reader to move into the cancer field with confidence.

Introduction
Lessons from epidemiology
Causes of cancer
Signalling in normal cells
'Cancer genes': mutations and cancer development
What is a tumour?
Cancer signalling networks
The future of cancer prevention, diagnosis and treatment
The future of cancer in the post-genomic era
Ten major cancers at a glance
Appendix. Targets of specific anti-cancer drugs
Glossary
Further reading
Index

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